Overview

Cellxgene Gateway allows you to use the Cellxgene Server provided by the Chan Zuckerberg Institute (https://github.com/chanzuckerberg/cellxgene) with multiple datasets. It displays an index of available h5ad (anndata) files. When a user clicks on a file name, it launches a Cellxgene Server instance that loads that particular data file and once it is available proxies requests to that server.

Running locally

This project requires python 3.6 or higher. Please check your version with

python --version
Set up a venv with

    python -m venv .cellxgene-gateway
    source .cellxgene-gateway/bin/activate

Install requirements with

    pip install -r requirements.txt

Prepare a folder with .h5ad files, for example

    mkdir cellxgene_data
    wget https://github.com/chanzuckerberg/cellxgene/raw/master/example-dataset/pbmc3k.h5ad -O ../cellxgene_data/pbmc3k.h5ad

Copy run.sh.example to run.sh:

     cp run.sh.example run.sh

run.sh defines various environment variables:

DEPLOYMENT_ENV - expects 'dev', 'tst' or 'prd'
CELLXGENE_LOCATION - the location of the cellxgene executable, e.g. ~/anaconda2/envs/cellxgene/bin/cellxgene
CELLXGENE_DATA - a directory that can contain subdirectories with .h5ad data files, without trailing slash, e.g. /mnt/cellxgene_data
GATEWAY_HOST - the hostname and port that the gateway will run on, typically localhost:5005 if running locally
GATEWAY_PROTOCOL - typically http when running locally, can be https when deployed if the gateway is behind a load balancer or reverse proxy.

The defaults should be fine if you set up a venv and cellxgene_data folder as above.

Finally, execute run.sh:

source run.sh

Customization

The current paradigm for customization is to modify files during a build or deployment phase:

To modify CSS or JS on particular gateway pages, overwrite or append to the templates
To add script tags such as for user analytics to all pages, overwrite the extra_scripts.py file.
- these scripts will also be run on the pages served by cellxgene server via the --scripts parameter
- See https://github.com/chanzuckerberg/cellxgene/pull/680 for details on --scripts parameter

Currently we use a build.sh that copies the gateway to a "build" directory before modifying with sed and the like.

Development

Running Linters

pip install isort flake8 black

isort -rc .

flake8 .

black .

Getting Help

If you need help for any reason, please make a github ticket. One of the contributors should help you out.

Contributors

Niket Patel - https://github.com/NiketPatel9
Alok Saldanha - https://github.com/alokito
Yohann Potier - https://github.com/ypotier

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