Refactor czi_hosted and server into backend directory, pull common code into backend/common, refactor tests (#2102)

* move local_server -> backend/server server-> backend/czi_hosted, pull common code into backend/common update imports, tests and make commands
This commit is contained in:
Madison Dunitz
2021-03-26 00:27:07 -05:00
committed by GitHub
parent e6e358ddc8
commit 78c9d24ed4
425 changed files with 734 additions and 5317 deletions
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from abc import ABCMeta, abstractmethod
import fastobo
import fsspec
from server.common.errors import OntologyLoadFailure
from server.common.utils.type_conversion_utils import get_schema_type_hint_of_array
class Annotations(metaclass=ABCMeta):
""" baseclass for annotations, including ontologies"""
""" our default ontology is the PURL for the Cell Ontology.
See http://www.obofoundry.org/ontology/cl.html """
DefaultOnotology = "http://purl.obolibrary.org/obo/cl.obo"
def __init__(self):
self.ontology_data = None
def load_ontology(self, path):
"""Load and parse ontologies - currently support OBO files only."""
if path is None:
path = self.DefaultOnotology
try:
with fsspec.open(path) as f:
obo = fastobo.iter(f)
terms = filter(lambda stanza: type(stanza) is fastobo.term.TermFrame, obo)
names = [tag.name for term in terms for tag in term if type(tag) is fastobo.term.NameClause]
self.ontology_data = names
except FileNotFoundError as e:
raise OntologyLoadFailure("Unable to find OBO ontology path") from e
except SyntaxError as e:
raise OntologyLoadFailure(f"{path}:{e.lineno}:{e.offset} OBO syntax error, unable to read ontology") from e
except Exception as e:
raise OntologyLoadFailure(f"{path}:Error loading OBO file") from e
def get_schema(self, data_adaptor):
schema = []
labels = self.read_labels(data_adaptor)
if labels is not None and not labels.empty:
for col in labels.columns:
col_schema = dict(name=col, writable=True)
col_schema.update(get_schema_type_hint_of_array(labels[col]))
schema.append(col_schema)
return schema
@abstractmethod
def set_collection(self, name):
"""set or create a new annotation collection"""
pass
@abstractmethod
def read_labels(self, data_adaptor):
"""Return the labels as a pandas.DataFrame"""
pass
@abstractmethod
def write_labels(self, df, data_adaptor):
"""Write the labels (df) to a persistent storage such that it can later be read"""
pass
@abstractmethod
def update_parameters(self, parameters, data_adaptor):
"""Update configuration parameters that describe information about the annotations feature"""
pass
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import json
import os
import re
import time
import pandas as pd
import tiledb
from flask import current_app
from server.common.annotations.annotations import Annotations
from server.common.errors import AnnotationCategoryNameError
from server.common.utils.sanitization_utils import sanitize_values_in_list
from server.common.utils.type_conversion_utils import get_dtypes_and_schemas_of_dataframe, get_dtype_of_array
from server.db.cellxgene_orm import Annotation
class AnnotationsHostedTileDB(Annotations):
CXG_ANNO_COLLECTION = "cxg_anno_collection"
def __init__(self, directory_path, db):
super().__init__()
self.db = db
if directory_path[-1] == "/":
self.directory_path = directory_path
else:
self.directory_path = directory_path + "/"
def check_category_names(self, df):
original_category_names = df.keys().to_list()
sanitized_category_names = set(sanitize_values_in_list(original_category_names).values())
unsanitary_original_category_names = set(original_category_names).difference(sanitized_category_names)
if unsanitary_original_category_names:
raise AnnotationCategoryNameError(
f"{unsanitary_original_category_names} are not valid category names, please resubmit"
)
def get_user_name(self):
return current_app.auth.get_user_name()
def get_user_id(self):
return current_app.auth.get_user_id()
def is_safe_collection_name(self, name):
"""
return true if this is a safe collection name
this is ultra conservative. If we want to allow full legal file name syntax,
we could look at modules like `pathvalidate`
"""
if name is None:
return False
return re.match(r"^[\w\-]+$", name) is not None
def set_collection(self, name):
self.CXG_ANNO_COLLECTION = name
def read_labels(self, data_adaptor):
user_id = self.get_user_id()
if user_id is None:
return
dataset_name = data_adaptor.get_location()
dataset_id = self.db.get_or_create_dataset(dataset_name)
annotation_object = self.db.query_for_most_recent(
Annotation, [Annotation.user_id == user_id, Annotation.dataset_id == dataset_id]
)
if annotation_object:
if annotation_object.tiledb_uri == "":
# this mean the user has removed all the categories.
return None
try:
df = tiledb.open(annotation_object.tiledb_uri)
except tiledb.TileDBError:
# don't crash if the annotations file is missing or can't be read.
current_app.logger.warning(f"Cannot read annotation file: {annotation_object.tiledb_uri}")
return None
pandas_df = self.convert_to_pandas_df(df, annotation_object.schema_hints)
return pandas_df
else:
return None
def convert_to_pandas_df(self, tileDBArray, schema_hints):
repr_meta = None
index_dims = None
schema_hints = json.loads(schema_hints)
if "__pandas_attribute_repr" in tileDBArray.meta:
# backwards compatibility... unsure if necessary at this point
repr_meta = json.loads(tileDBArray.meta["__pandas_attribute_repr"])
if "__pandas_index_dims" in tileDBArray.meta:
index_dims = json.loads(tileDBArray.meta["__pandas_index_dims"])
data = tileDBArray[:]
indexes = list()
for col_name, col_val in data.items():
# If the column values are byte literals, decode them
if isinstance(col_val[0], bytes):
col_val = [value.decode("utf-8") for value in col_val]
if schema_hints and col_name in schema_hints:
type = schema_hints.get(col_name).get("type")
if type and type == "categorical":
new_col = pd.Series(col_val, dtype="category")
data[col_name] = new_col
elif repr_meta and col_name in repr_meta:
new_col = pd.Series(col_val, dtype=repr_meta[col_name])
data[col_name] = new_col
elif index_dims and col_name in index_dims:
new_col = pd.Series(col_val, dtype=index_dims[col_name])
data[col_name] = new_col
indexes.append(col_name)
new_df = pd.DataFrame.from_dict(data)
if len(indexes) > 0:
new_df.set_index(indexes, inplace=True)
return new_df
def write_labels(self, df, data_adaptor):
auth_user_id = self.get_user_id()
user_name = self.get_user_name()
timestamp = time.time()
dataset_location = data_adaptor.get_location()
dataset_id = self.db.get_or_create_dataset(dataset_location)
dataset_name = data_adaptor.get_title()
user_id = self.db.get_or_create_user(auth_user_id)
"""
NOTE: The uri contains the dataset name, user name and a timestamp as a convenience for debugging purposes.
People may have the same name and time.time() can be server dependent.
See - https://docs.python.org/2/library/time.html#time.time
The annotations objects in the database should be used as the source of truth about who an annotation belongs
to (for authorization purposes) and what time it was created (for garbage collection).
"""
uri = f"{self.directory_path}{dataset_name}/{user_name}/{timestamp}"
if uri.startswith("s3://"):
pass
else:
os.makedirs(uri, exist_ok=True)
_, dataframe_schema_type_hints = get_dtypes_and_schemas_of_dataframe(df)
if not df.empty:
self.check_category_names(df)
# convert to tiledb datatypes
for col in df:
df[col] = df[col].astype(get_dtype_of_array(df[col]))
tiledb.from_pandas(uri, df, sparse=True)
else:
uri = ""
annotation = Annotation(
tiledb_uri=uri,
user_id=user_id,
dataset_id=str(dataset_id),
schema_hints=json.dumps(dataframe_schema_type_hints),
)
self.db.session.add(annotation)
self.db.session.commit()
def update_parameters(self, parameters, data_adaptor):
params = {}
params["annotations"] = True
params["user_annotation_collection_name_enabled"] = False
if self.ontology_data:
params["annotations_cell_ontology_enabled"] = True
params["annotations_cell_ontology_terms"] = self.ontology_data
else:
params["annotations_cell_ontology_enabled"] = False
parameters.update(params)
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import base64
import os
import re
import threading
from datetime import datetime
from hashlib import blake2b
import pandas as pd
from flask import session, has_request_context, current_app
from server import __version__ as cellxgene_version
from server.common.annotations.annotations import Annotations
from server.common.errors import AnnotationsError
class AnnotationsLocalFile(Annotations):
CXG_ANNO_COLLECTION = "cxg_anno_collection"
def __init__(self, output_dir, output_file):
super().__init__()
self.output_dir = output_dir
self.output_file = output_file
# lock used to protect label file write ops
self.label_lock = threading.RLock()
# cache the most recent annotations
self.last_fname = None
self.last_labels = None
def is_safe_collection_name(self, name):
"""
return true if this is a safe collection name
this is ultra conservative. If we want to allow full legal file name syntax,
we could look at modules like `pathvalidate`
"""
if name is None:
return False
return re.match(r"^[\w\-]+$", name) is not None
def set_collection(self, name):
session[self.CXG_ANNO_COLLECTION] = name
session.permanent = True
def get_collection(self):
if session is None:
return None
return session.get(self.CXG_ANNO_COLLECTION)
def read_labels(self, data_adaptor):
if has_request_context():
if not current_app.auth.is_user_authenticated():
return pd.DataFrame()
fname = self._get_filename(data_adaptor)
with self.label_lock:
if fname is not None and os.path.exists(fname) and os.path.getsize(fname) > 0:
# returned the cached labels if possible, otherwise read them from the file
if fname == self.last_fname:
return self.last_labels
else:
labels = pd.read_csv(
fname, dtype="category", index_col=0, header=0, comment="#", keep_default_na=False
)
# update the cache
self.last_fname = fname
self.last_labels = labels
return labels
else:
return pd.DataFrame()
def write_labels(self, df, data_adaptor):
# update our internal state and save it. Multi-threading often enabled,
# so treat this as a critical section.
with self.label_lock:
lastmod = data_adaptor.get_last_mod_time()
lastmodstr = "'unknown'" if lastmod is None else lastmod.isoformat(timespec="seconds")
header = (
f"# Annotations generated on {datetime.now().isoformat(timespec='seconds')} "
f"using cellxgene version {cellxgene_version}\n"
f"# Input data file was {data_adaptor.get_location()}, "
f"which was last modified on {lastmodstr}\n"
)
fname = self._get_filename(data_adaptor)
self._backup(fname)
if not df.empty:
with open(fname, "w", newline="") as f:
if header is not None:
f.write(header)
df.to_csv(f)
else:
open(fname, "w").close()
# update the cache
self.last_fname = fname
self.last_labels = df
def _get_userdata_idhash(self, data_adaptor):
"""
Return a short hash that weakly identifies the user and dataset.
Used to create safe annotations output file names.
"""
uid = current_app.auth.get_user_id()
id = (uid + data_adaptor.get_location()).encode()
idhash = base64.b32encode(blake2b(id, digest_size=5).digest()).decode("utf-8")
return idhash
def _get_output_dir(self):
if self.output_dir:
return self.output_dir
if self.output_file:
return os.path.dirname(self.path.abspath(self.output_dir))
return os.getcwd()
def _get_filename(self, data_adaptor):
""" return the current annotation file name """
if self.output_file:
return self.output_file
# we need to generate a file name, which we can only do if we have a UID and collection name
if session is None:
raise AnnotationsError("unable to determine file name for annotations")
collection = self.get_collection()
if collection is None:
return None
if data_adaptor is None:
raise AnnotationsError("unable to determine file name for annotations")
idhash = self._get_userdata_idhash(data_adaptor)
return os.path.join(self._get_output_dir(), f"{collection}-{idhash}.csv")
def _backup(self, fname, max_backups=9):
"""
save N backups of file to backup_dir.
1. fname -> backup_dir/fname-TIME
2. delete excess files in backup_dir
"""
root, ext = os.path.splitext(fname)
backup_dir = f"{root}-backups"
# Make sure there is work to do
if not os.path.exists(fname):
return
# Ensure backup_dir exists
if not os.path.exists(backup_dir):
os.mkdir(backup_dir)
# Save current file to backup_dir
fname_base = os.path.basename(fname)
fname_base_root, fname_base_ext = os.path.splitext(fname_base)
# don't use ISO standard time format, as it contains characters illegal on some filesytems.
nowish = datetime.now().strftime("%Y-%m-%dT%H-%M-%S")
backup_fname = os.path.join(backup_dir, f"{fname_base_root}-{nowish}{fname_base_ext}")
if os.path.exists(backup_fname):
os.remove(backup_fname)
os.rename(fname, backup_fname)
# prune the backup_dir to max number of backup files, keeping the most recent backups
backups = list(filter(lambda s: s.startswith(fname_base_root), os.listdir(backup_dir)))
excess_count = len(backups) - max_backups
if excess_count > 0:
backups.sort()
for bu in backups[0:excess_count]:
os.remove(os.path.join(backup_dir, bu))
def update_parameters(self, parameters, data_adaptor):
params = {}
params["annotations"] = True
params["user_annotation_collection_name_enabled"] = True
if self.ontology_data:
params["annotations_cell_ontology_enabled"] = True
params["annotations_cell_ontology_terms"] = self.ontology_data
else:
params["annotations_cell_ontology_enabled"] = False
if self.output_file is not None:
# user has hard-wired the name of the annotation data collection
fname = os.path.basename(self.output_file)
collection_fname = os.path.splitext(fname)[0]
params["annotations-data-collection-is-read-only"] = True
params["annotations-data-collection-name"] = collection_fname
elif session is not None:
collection = self.get_collection()
if current_app.auth.is_user_authenticated():
params["annotations-user-data-idhash"] = self._get_userdata_idhash(data_adaptor)
params["annotations-data-collection-is-read-only"] = False
params["annotations-data-collection-name"] = collection
parameters.update(params)
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import logging
import boto3
from flask import json
from server.common.errors import SecretKeyRetrievalError
def get_secret_key(region_name, secret_name):
session = boto3.session.Session()
client = session.client(service_name="secretsmanager", region_name=region_name)
try:
get_secret_value_response = client.get_secret_value(SecretId=secret_name)
if "SecretString" in get_secret_value_response:
var = get_secret_value_response["SecretString"]
secret = json.loads(var)
return secret
except Exception as e:
logging.critical(f"Caught exception during get_secret_key, {e}", exc_info=True)
raise SecretKeyRetrievalError(str(e))
return None
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import re
from server.common.errors import ColorFormatException
HEX_COLOR_FORMAT = re.compile("^#[a-fA-F0-9]{6,6}$")
# https://www.w3.org/TR/css-color-4/#named-colors
CSS4_NAMED_COLORS = dict(
aliceblue="#f0f8ff",
antiquewhite="#faebd7",
aqua="#00ffff",
aquamarine="#7fffd4",
azure="#f0ffff",
beige="#f5f5dc",
bisque="#ffe4c4",
black="#000000",
blanchedalmond="#ffebcd",
blue="#0000ff",
blueviolet="#8a2be2",
brown="#a52a2a",
burlywood="#deb887",
cadetblue="#5f9ea0",
chartreuse="#7fff00",
chocolate="#d2691e",
coral="#ff7f50",
cornflowerblue="#6495ed",
cornsilk="#fff8dc",
crimson="#dc143c",
cyan="#00ffff",
darkblue="#00008b",
darkcyan="#008b8b",
darkgoldenrod="#b8860b",
darkgray="#a9a9a9",
darkgreen="#006400",
darkgrey="#a9a9a9",
darkkhaki="#bdb76b",
darkmagenta="#8b008b",
darkolivegreen="#556b2f",
darkorange="#ff8c00",
darkorchid="#9932cc",
darkred="#8b0000",
darksalmon="#e9967a",
darkseagreen="#8fbc8f",
darkslateblue="#483d8b",
darkslategray="#2f4f4f",
darkslategrey="#2f4f4f",
darkturquoise="#00ced1",
darkviolet="#9400d3",
deeppink="#ff1493",
deepskyblue="#00bfff",
dimgray="#696969",
dimgrey="#696969",
dodgerblue="#1e90ff",
firebrick="#b22222",
floralwhite="#fffaf0",
forestgreen="#228b22",
fuchsia="#ff00ff",
gainsboro="#dcdcdc",
ghostwhite="#f8f8ff",
gold="#ffd700",
goldenrod="#daa520",
gray="#808080",
green="#008000",
greenyellow="#adff2f",
grey="#808080",
honeydew="#f0fff0",
hotpink="#ff69b4",
indianred="#cd5c5c",
indigo="#4b0082",
ivory="#fffff0",
khaki="#f0e68c",
lavender="#e6e6fa",
lavenderblush="#fff0f5",
lawngreen="#7cfc00",
lemonchiffon="#fffacd",
lightblue="#add8e6",
lightcoral="#f08080",
lightcyan="#e0ffff",
lightgoldenrodyellow="#fafad2",
lightgray="#d3d3d3",
lightgreen="#90ee90",
lightgrey="#d3d3d3",
lightpink="#ffb6c1",
lightsalmon="#ffa07a",
lightseagreen="#20b2aa",
lightskyblue="#87cefa",
lightslategray="#778899",
lightslategrey="#778899",
lightsteelblue="#b0c4de",
lightyellow="#ffffe0",
lime="#00ff00",
limegreen="#32cd32",
linen="#faf0e6",
magenta="#ff00ff",
maroon="#800000",
mediumaquamarine="#66cdaa",
mediumblue="#0000cd",
mediumorchid="#ba55d3",
mediumpurple="#9370db",
mediumseagreen="#3cb371",
mediumslateblue="#7b68ee",
mediumspringgreen="#00fa9a",
mediumturquoise="#48d1cc",
mediumvioletred="#c71585",
midnightblue="#191970",
mintcream="#f5fffa",
mistyrose="#ffe4e1",
moccasin="#ffe4b5",
navajowhite="#ffdead",
navy="#000080",
oldlace="#fdf5e6",
olive="#808000",
olivedrab="#6b8e23",
orange="#ffa500",
orangered="#ff4500",
orchid="#da70d6",
palegoldenrod="#eee8aa",
palegreen="#98fb98",
paleturquoise="#afeeee",
palevioletred="#db7093",
papayawhip="#ffefd5",
peachpuff="#ffdab9",
peru="#cd853f",
pink="#ffc0cb",
plum="#dda0dd",
powderblue="#b0e0e6",
purple="#800080",
rebeccapurple="#663399",
red="#ff0000",
rosybrown="#bc8f8f",
royalblue="#4169e1",
saddlebrown="#8b4513",
salmon="#fa8072",
sandybrown="#f4a460",
seagreen="#2e8b57",
seashell="#fff5ee",
sienna="#a0522d",
silver="#c0c0c0",
skyblue="#87ceeb",
slateblue="#6a5acd",
slategray="#708090",
slategrey="#708090",
snow="#fffafa",
springgreen="#00ff7f",
steelblue="#4682b4",
tan="#d2b48c",
teal="#008080",
thistle="#d8bfd8",
tomato="#ff6347",
turquoise="#40e0d0",
violet="#ee82ee",
wheat="#f5deb3",
white="#ffffff",
whitesmoke="#f5f5f5",
yellow="#ffff00",
yellowgreen="#9acd32",
)
def convert_color_to_hex_format(unknown):
"""
Try to convert color info to a hex triplet string https://en.wikipedia.org/wiki/Web_colors#Hex_triplet.
The function accepts for the following formats:
- A CSS4 color name, as supported by matplotlib https://matplotlib.org/3.1.0/gallery/color/named_colors.html
- RGB tuple/list with values ranging from 0.0 to 1.0, as in [0.5, 0.75, 1.0]
- RFB tuple/list with values ranging from 0 to 255, as in [128, 192, 255]
- Hex triplet string, as in "#08c0ff"
:param unknown: color info of unknown format
:return: a hex triplet representing that color
"""
try:
if type(unknown) in (list, tuple) and len(unknown) == 3:
if all(0.0 <= ele <= 1.0 for ele in unknown):
tup = tuple(int(ele * 255) for ele in unknown)
elif all(0 <= ele <= 255 and isinstance(ele, int) for ele in unknown):
tup = tuple(unknown)
else:
raise ColorFormatException("Unknown color iterable format!")
return "#%02x%02x%02x" % tup
elif isinstance(unknown, str) and unknown.lower() in CSS4_NAMED_COLORS:
return CSS4_NAMED_COLORS[unknown.lower()]
elif isinstance(unknown, str) and HEX_COLOR_FORMAT.match(unknown):
return unknown.lower()
else:
raise ColorFormatException("Unknown color format type!")
except Exception as e:
raise ColorFormatException(e)
def convert_anndata_category_colors_to_cxg_category_colors(data):
"""
Convert color information from anndata files to the cellxgene color data format as described below:
{
"<category_name>": {
"<label_name>": "<color_hex_code>",
...
},
...
}
For more on the cxg color data structure, see https://github.com/chanzuckerberg/cellxgene/issues/1307.
For more on the anndata color data structure, see
https://github.com/chanzuckerberg/cellxgene/issues/1152#issuecomment-587276178.
Handling of malformed data:
- For any color info in a adata.uns[f"{category}_colors"] color array that convert_color_to_hex_format cannot
convert to a hex triplet string, a ColorFormatException is raised
- No category_name key group is returned for adata.uns[f"{category}_colors"] keys for which there is no
adata.obs[f"{category}"] key
:param data: the anndata file
:return: cellxgene color data structure as described above
"""
cxg_colors = dict()
color_key_suffix = "_colors"
for uns_key in data.uns.keys():
# find uns array that describes colors for a category
if not uns_key.endswith(color_key_suffix):
continue
# check to see if we actually have observations for that category
category_name = uns_key[: -len(color_key_suffix)]
if category_name not in data.obs.keys():
continue
# create the cellxgene color entry for this category
cxg_colors[category_name] = dict(
zip(data.obs[category_name].cat.categories, [convert_color_to_hex_format(c) for c in data.uns[uns_key]])
)
return cxg_colors
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from server.common.aws_secret_utils import get_secret_key # noqa F504
DEFAULT_SERVER_PORT = 5005
BIG_FILE_SIZE_THRESHOLD = 100 * 2 ** 20 # 100MB
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import yaml
from flatten_dict import unflatten
from server.default_config import get_default_config
from server.common.config.dataset_config import DatasetConfig
from server.common.config.server_config import ServerConfig
from server.common.config.external_config import ExternalConfig
from server.common.errors import ConfigurationError
class AppConfig(object):
"""
AppConfig stores all the configuration for cellxgene.
AppConfig contains one or more DatasetConfig(s) and one ServerConfig.
The server_config contains attributes that refer to the server process as a whole.
The default_dataset_config refers to attributes that are associated with the features and
presentations of a dataset.
The dataset config attributes can be overridden depending on the url by which the
dataset was accessed. These are stored in dataroot_config.
AppConfig has methods to initialize, modify, and access the configuration.
"""
def __init__(self):
# the default configuration (see default_config.py)
# TODO @madison -- if we always read from the default config (hard coded path) can we set those values as
# defaults within the config class?
self.default_config = get_default_config()
# the server configuration
self.server_config = ServerConfig(self, self.default_config["server"])
# the dataset config, unless overridden by an entry in dataroot_config
self.default_dataset_config = DatasetConfig(None, self, self.default_config["dataset"])
# a dictionary of keys to DatasetConfig objects. Each key must exist in the multi_dataset__dataroot
# attribute of the server_config. The default dataset config will apply to all datasets unless a different set
# of config vars was passed for a specific dataset under the multidataset config. For example:
"""
per_dataset_config:
d1:
user_annotations:
enable: false
d2:
user_annotations:
enable: true
"""
# dataroot config
self.dataroot_config = {}
# external config
self.external_config = ExternalConfig(self, self.default_config["external"])
# Set to true when config_completed is called
self.is_completed = False
def get_dataset_config(self, dataroot_key):
if self.server_config.single_dataset__datapath:
return self.default_dataset_config
else:
return self.dataroot_config.get(dataroot_key, self.default_dataset_config)
def check_config(self):
"""Verify all the attributes in the config have been type checked"""
if not self.is_completed:
raise ConfigurationError("The configuration has not been completed")
self.server_config.check_config()
self.default_dataset_config.check_config()
for dataset_config in self.dataroot_config.values():
dataset_config.check_config()
self.external_config.check_config()
def update_server_config(self, **kw):
self.server_config.update(**kw)
self.is_complete = False
def update_default_dataset_config(self, **kw):
self.default_dataset_config.update(**kw)
# update all the other dataset configs, if any
for value in self.dataroot_config.values():
value.update(**kw)
self.is_complete = False
def update_single_config_from_path_and_value(self, path, value):
"""Update a single config parameter with the value.
Path is a list of string, that gives a path to the config parameter to be updated.
For example, path may be ["server","app","port"].
"""
self.is_complete = False
if not isinstance(path, list):
raise ConfigurationError(f"path must be a list of strings, got '{str(path)}'")
for part in path:
if not isinstance(part, str):
raise ConfigurationError(f"path must be a list of strings, got '{str(path)}'")
if len(path) < 1 or path[0] not in ("server", "dataset", "per_dataset_config"):
raise ConfigurationError("path must start with 'server', 'dataset', or 'per_dataset_config'")
if path[0] == "server":
attr = "__".join(path[1:])
try:
self.update_server_config(**{attr: value})
except ConfigurationError:
raise ConfigurationError(f"unknown config parameter at path: '{str(path)}'")
elif path[0] == "dataset":
attr = "__".join(path[1:])
try:
self.update_default_dataset_config(**{attr: value})
except ConfigurationError:
raise ConfigurationError(f"unknown config parameter at path: '{str(path)}'")
elif path[0] == "per_dataset_config":
if len(path) < 2:
raise ConfigurationError(f"missing dataroot when using per_dataset_config: got '{path}'")
dataroot = path[1]
if dataroot not in self.dataroot_config:
dataroots = str(list(self.dataroot_config.keys()))
raise ConfigurationError(
f"unknown dataroot when using per_dataset_config: got '{path}',"
f" dataroots specified in config are {dataroots}"
)
attr = "__".join(path[2:])
try:
self.dataroot_config[dataroot].update(**{attr: value})
except ConfigurationError:
raise ConfigurationError(f"unknown config parameter at path: '{str(path)}'")
def update_from_config_file(self, config_file):
try:
with open(config_file) as yml_file:
config = yaml.safe_load(yml_file)
except yaml.YAMLError as e:
raise ConfigurationError(f"The specified config file contained an error: {e}")
except OSError as e:
raise ConfigurationError(f"Issue retrieving the specified config file: {e}")
if config.get("server"):
self.server_config.update_from_config(config["server"], "server")
if config.get("dataset"):
self.default_dataset_config.update_from_config(config["dataset"], "dataset")
per_dataset_config = config.get("per_dataset_config", {})
for key, dataroot_config in per_dataset_config.items():
# first create and initialize the dataroot with the default config
self.add_dataroot_config(key, **config["dataset"])
# then apply the per dataset configuration
self.dataroot_config[key].update_from_config(dataroot_config, f"per_dataset_config__{key}")
if config.get("external"):
self.external_config.update_from_config(config["external"], "external")
self.is_complete = False
def config_to_dict(self):
"""return the configuration as an unflattened dict"""
server = self.server_config.create_mapping(self.server_config.default_config)
dataset = self.default_dataset_config.create_mapping(self.default_dataset_config.default_config)
external = self.external_config.create_mapping(self.external_config.default_config)
config = dict(server={}, dataset={})
for attrname in server.keys():
config["server__" + attrname] = getattr(self.server_config, attrname)
for attrname in dataset.keys():
config["dataset__" + attrname] = getattr(self.default_dataset_config, attrname)
if self.dataroot_config:
config["per_dataset_config"] = {}
for dataroot_tag, dataroot_config in self.dataroot_config.items():
dataset = dataroot_config.create_mapping(dataroot_config.default_config)
for attrname in dataset.keys():
config[f"per_dataset_config__{dataroot_tag}__" + attrname] = getattr(dataroot_config, attrname)
for attrname in external.keys():
config["external__" + attrname] = getattr(self.external_config, attrname)
config = unflatten(config, splitter=lambda key: key.split("__"))
return config
def write_config(self, config_file):
"""output the config to a yaml file"""
config = self.config_to_dict()
yaml.dump(config, open(config_file, "w"))
def changes_from_default(self):
"""Return all the attribute that are different from the default"""
diff_server = self.server_config.changes_from_default()
diff_dataset = self.default_dataset_config.changes_from_default()
diff_external = self.external.changes_from_default()
diff = dict(server=diff_server, dataset=diff_dataset, external=diff_external)
return diff
def add_dataroot_config(self, dataroot_tag, **kw):
"""Create a new dataset config object based on the default dataset config, and kw parameters"""
if dataroot_tag in self.dataroot_config:
raise ConfigurationError(f"dataroot config already exists: {dataroot_tag}")
if type(self.server_config.multi_dataset__dataroot) != dict:
raise ConfigurationError("The server__multi_dataset__dataroot must be a dictionary")
if dataroot_tag not in self.server_config.multi_dataset__dataroot:
raise ConfigurationError(f"The dataroot_tag ({dataroot_tag}) not found in server__multi_dataset__dataroot")
self.is_completed = False
self.dataroot_config[dataroot_tag] = DatasetConfig(dataroot_tag, self, self.default_config["dataset"])
flat_config = self.default_dataset_config.create_mapping(self.default_dataset_config.default_config)
config = {key: value[1] for key, value in flat_config.items()}
self.dataroot_config[dataroot_tag].update(**config)
self.dataroot_config[dataroot_tag].update_from_config(kw, dataroot_tag)
def complete_config(self, messagefn=None):
"""The configure options are checked, and any additional setup based on the config
parameters is done"""
if messagefn is None:
def noop(message):
pass
messagefn = noop
# TODO: to give better error messages we can add a mapping between where each config
# attribute originated (e.g. command line argument or config file), then in the error
# messages we can give correct context for attributes with bad value.
context = dict(messagefn=messagefn)
# complete config for external_config first, since this may update values in the other sections
self.external_config.complete_config(context)
self.server_config.complete_config(context)
self.default_dataset_config.complete_config(context)
for dataroot_config in self.dataroot_config.values():
dataroot_config.complete_config(context)
self.is_completed = True
self.check_config()
def get_matrix_data_cache_manager(self):
return self.server_config.matrix_data_cache_manager
def is_multi_dataset(self):
return self.server_config.multi_dataset__dataroot is not None
def get_title(self, data_adaptor):
return (
self.server_config.single_dataset__title
if self.server_config.single_dataset__title
else data_adaptor.get_title()
)
def get_about(self, data_adaptor):
return (
self.server_config.single_dataset__about
if self.server_config.single_dataset__about
else data_adaptor.get_about()
)
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import copy
from flatten_dict import flatten
from server.common.errors import ConfigurationError
class BaseConfig(object):
"""
This class handles the mechanics of updating and checking attributes.
Derived classes are expected to store the actual attributes
Currently DatasetConfig and ServerConfig both inherit from BaseConfig.
"""
def __init__(self, app_config, default_config, dictval_cases={}):
# reference back to the app_config
self.app_config = app_config
# the complete set of attributes and their default values (unflattened)
self.default_config = default_config
# attributes where the value may be a dict (and therefore are not flattened)
self.dictval_cases = dictval_cases
# used to make sure every attribute value is checked
self.attr_checked = {key_name: False for key_name in self.create_mapping(default_config).keys()}
def create_mapping(self, config):
"""
Create a dictionary where the keys are the name of attributes (using double underscore convention)
For example: authentication__type
The values are a tuple,
- the first item of the tuple is a tuple of path elements (location in config 'tree')
- the second item is the value of the config parameter
For example: (('authentication', 'type'), 'session'))
"""
config_copy = copy.deepcopy(config)
mapping = {}
# special cases where the value could be a dict.
# If its value is not None, the entry is added to the mapping, and not included
# in the flattening below.
for dictval_case in self.dictval_cases:
cur = config_copy
for part in dictval_case[:-1]:
cur = cur.get(part, {})
val = cur.get(dictval_case[-1])
if val is not None:
key = "__".join(dictval_case)
mapping[key] = (dictval_case, val)
del cur[dictval_case[-1]]
flat_config = flatten(config_copy)
for key, value in flat_config.items():
# name of the attribute
attr = "__".join(key)
mapping[attr] = (key, value)
return mapping
def validate_correct_type_of_configuration_attribute(self, attrname, vtype):
val = getattr(self, attrname)
if type(vtype) in (list, tuple):
if type(val) not in vtype:
tnames = ",".join([x.__name__ for x in vtype])
raise ConfigurationError(
f"Invalid type for attribute: {attrname}, expected types ({tnames}), got {type(val).__name__}"
)
else:
if type(val) != vtype:
raise ConfigurationError(
f"Invalid type for attribute: {attrname}, "
f"expected type {vtype.__name__}, got {type(val).__name__}"
)
self.attr_checked[attrname] = True
def check_config(self):
mapping = self.create_mapping(self.default_config)
for key in mapping.keys():
if not self.attr_checked[key]:
raise ConfigurationError(f"The attr '{key}' has not been checked")
def update(self, **kw):
"""Update the attributes defined in kw with their new values."""
for key, value in kw.items():
if not hasattr(self, key):
# check if the key is setting into a dictval entry.
found_dictval = False
for dictval in self.dictval_cases:
dictvalname = "__".join(dictval)
if dictvalname + "__" in key:
dictkey = key[len(dictvalname) + 2 :]
curdictval = getattr(self, dictvalname)
if curdictval is None:
setattr(self, dictvalname, dict(dictkey=value))
else:
curdictval[dictkey] = value
found_dictval = True
break
if found_dictval:
continue
raise ConfigurationError(f"unknown config parameter {key}.")
try:
if type(value) == tuple:
# convert tuple values to list values
value = list(value)
setattr(self, key, value)
except KeyError:
raise ConfigurationError(f"Unable to set config parameter {key}.")
self.attr_checked[key] = False
def update_from_config(self, config, prefix):
mapping = self.create_mapping(config)
for attr, (key, value) in mapping.items():
if not hasattr(self, attr):
raise ConfigurationError(f"Unknown key from config file: {prefix}__{attr}")
setattr(self, attr, value)
self.attr_checked[attr] = False
def changes_from_default(self):
"""Return all the attribute that are different from the default"""
mapping = self.create_mapping(self.default_config)
diff = []
for attrname, (key, defval) in mapping.items():
curval = getattr(self, attrname)
if curval != defval:
diff.append((attrname, curval, defval))
return diff
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@@ -1,122 +0,0 @@
from server import display_version as cellxgene_display_version
def get_client_config(app_config, data_adaptor):
"""
Return the configuration as required by the /config REST route
"""
server_config = app_config.server_config
dataset_config = data_adaptor.dataset_config
annotation = dataset_config.user_annotations
auth = server_config.auth
# FIXME The current set of config is not consistently presented:
# we have camalCase, hyphen-text, and underscore_text
# make sure the configuration has been checked.
app_config.check_config()
# display_names
title = app_config.get_title(data_adaptor)
about = app_config.get_about(data_adaptor)
display_names = dict(engine=data_adaptor.get_name(), dataset=title)
# library_versions
library_versions = {}
library_versions.update(data_adaptor.get_library_versions())
library_versions["cellxgene"] = cellxgene_display_version
# links
links = {"about-dataset": about}
# parameters
parameters = {
"layout": dataset_config.embeddings__names,
"max-category-items": dataset_config.presentation__max_categories,
"obs_names": server_config.single_dataset__obs_names,
"var_names": server_config.single_dataset__var_names,
"diffexp_lfc_cutoff": dataset_config.diffexp__lfc_cutoff,
"backed": server_config.adaptor__anndata_adaptor__backed,
"disable-diffexp": not dataset_config.diffexp__enable,
"enable-reembedding": dataset_config.embeddings__enable_reembedding,
"annotations": False,
"annotations_file": None,
"annotations_dir": None,
"annotations_cell_ontology_enabled": False,
"annotations_cell_ontology_obopath": None,
"annotations_cell_ontology_terms": None,
"custom_colors": dataset_config.presentation__custom_colors,
"diffexp-may-be-slow": False,
"about_legal_tos": dataset_config.app__about_legal_tos,
"about_legal_privacy": dataset_config.app__about_legal_privacy,
}
# corpora dataset_props
# TODO/Note: putting info from the dataset into the /config is not ideal.
# However, it is definitely not part of /schema, and we do not have a top-level
# route for data properties. Consider creating one at some point.
corpora_props = data_adaptor.get_corpora_props()
if corpora_props and "default_embedding" in corpora_props:
default_embedding = corpora_props["default_embedding"]
if isinstance(default_embedding, str) and default_embedding.startswith("X_"):
default_embedding = default_embedding[2:] # drop X_ prefix
if default_embedding in data_adaptor.get_embedding_names():
parameters["default_embedding"] = default_embedding
data_adaptor.update_parameters(parameters)
if annotation:
annotation.update_parameters(parameters, data_adaptor)
# gather it all together
client_config = {}
config = client_config["config"] = {}
config["displayNames"] = display_names
config["library_versions"] = library_versions
config["links"] = links
config["parameters"] = parameters
config["corpora_props"] = corpora_props
config["limits"] = {
"column_request_max": server_config.limits__column_request_max,
"diffexp_cellcount_max": server_config.limits__diffexp_cellcount_max,
}
if dataset_config.app__authentication_enable and auth.is_valid_authentication_type():
config["authentication"] = {
"requires_client_login": auth.requires_client_login(),
}
if auth.requires_client_login():
config["authentication"].update(
{
# Todo why are these stored on the data_adaptor?
"login": auth.get_login_url(data_adaptor),
"logout": auth.get_logout_url(data_adaptor),
}
)
return client_config
def get_client_userinfo(app_config, data_adaptor):
"""
Return the userinfo as required by the /userinfo REST route
"""
server_config = app_config.server_config
dataset_config = data_adaptor.dataset_config
auth = server_config.auth
# make sure the configuration has been checked.
app_config.check_config()
if dataset_config.app__authentication_enable and auth.is_valid_authentication_type():
userinfo = {}
userinfo["userinfo"] = {
"is_authenticated": auth.is_user_authenticated(),
"username": auth.get_user_name(),
"user_id": auth.get_user_id(),
"email": auth.get_user_email(),
"picture": auth.get_user_picture(),
}
return userinfo
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@@ -1,230 +0,0 @@
import os
from os.path import splitext, isdir
from server.common.annotations.hosted_tiledb import AnnotationsHostedTileDB
from server.common.annotations.local_file_csv import AnnotationsLocalFile
from server.common.config.base_config import BaseConfig
from server.common.errors import ConfigurationError, OntologyLoadFailure
from server.compute.scanpy import get_scanpy_module
from server.data_common.matrix_loader import MatrixDataLoader, MatrixDataType
from server.db.db_utils import DbUtils
class DatasetConfig(BaseConfig):
"""Manages the config attribute associated with a dataset."""
def __init__(self, tag, app_config, default_config):
super().__init__(app_config, default_config)
self.tag = tag
try:
self.app__scripts = default_config["app"]["scripts"]
self.app__inline_scripts = default_config["app"]["inline_scripts"]
self.app__about_legal_tos = default_config["app"]["about_legal_tos"]
self.app__about_legal_privacy = default_config["app"]["about_legal_privacy"]
self.app__authentication_enable = default_config["app"]["authentication_enable"]
self.presentation__max_categories = default_config["presentation"]["max_categories"]
self.presentation__custom_colors = default_config["presentation"]["custom_colors"]
self.user_annotations__enable = default_config["user_annotations"]["enable"]
self.user_annotations__type = default_config["user_annotations"]["type"]
self.user_annotations__local_file_csv__directory = default_config["user_annotations"]["local_file_csv"][
"directory"
]
self.user_annotations__local_file_csv__file = default_config["user_annotations"]["local_file_csv"]["file"]
self.user_annotations__ontology__enable = default_config["user_annotations"]["ontology"]["enable"]
self.user_annotations__ontology__obo_location = default_config["user_annotations"]["ontology"][
"obo_location"
]
self.user_annotations__hosted_tiledb_array__db_uri = default_config["user_annotations"][
"hosted_tiledb_array"
]["db_uri"]
self.user_annotations__hosted_tiledb_array__hosted_file_directory = default_config["user_annotations"][
"hosted_tiledb_array"
]["hosted_file_directory"]
self.embeddings__names = default_config["embeddings"]["names"]
self.embeddings__enable_reembedding = default_config["embeddings"]["enable_reembedding"]
self.diffexp__enable = default_config["diffexp"]["enable"]
self.diffexp__lfc_cutoff = default_config["diffexp"]["lfc_cutoff"]
self.diffexp__top_n = default_config["diffexp"]["top_n"]
except KeyError as e:
raise ConfigurationError(f"Unexpected config: {str(e)}")
# The annotation object is created during complete_config and stored here.
self.user_annotations = None
def complete_config(self, context):
self.handle_app()
self.handle_presentation()
self.handle_user_annotations(context)
self.handle_embeddings()
self.handle_diffexp(context)
def handle_app(self):
self.validate_correct_type_of_configuration_attribute("app__scripts", list)
self.validate_correct_type_of_configuration_attribute("app__inline_scripts", list)
self.validate_correct_type_of_configuration_attribute("app__about_legal_tos", (type(None), str))
self.validate_correct_type_of_configuration_attribute("app__about_legal_privacy", (type(None), str))
self.validate_correct_type_of_configuration_attribute("app__authentication_enable", bool)
# scripts can be string (filename) or dict (attributes). Convert string to dict.
scripts = []
for script in self.app__scripts:
try:
if isinstance(script, str):
scripts.append({"src": script})
elif isinstance(script, dict) and isinstance(script["src"], str):
scripts.append(script)
else:
raise Exception
except Exception as e:
raise ConfigurationError(f"Scripts must be string or a dict containing an src key: {e}")
self.app__scripts = scripts
def handle_presentation(self):
self.validate_correct_type_of_configuration_attribute("presentation__max_categories", int)
self.validate_correct_type_of_configuration_attribute("presentation__custom_colors", bool)
def handle_user_annotations(self, context):
self.validate_correct_type_of_configuration_attribute("user_annotations__enable", bool)
self.validate_correct_type_of_configuration_attribute("user_annotations__type", str)
self.validate_correct_type_of_configuration_attribute(
"user_annotations__local_file_csv__directory", (type(None), str)
)
self.validate_correct_type_of_configuration_attribute(
"user_annotations__local_file_csv__file", (type(None), str)
)
self.validate_correct_type_of_configuration_attribute("user_annotations__ontology__enable", bool)
self.validate_correct_type_of_configuration_attribute(
"user_annotations__ontology__obo_location", (type(None), str)
)
self.validate_correct_type_of_configuration_attribute(
"user_annotations__hosted_tiledb_array__db_uri", (type(None), str)
)
self.validate_correct_type_of_configuration_attribute(
"user_annotations__hosted_tiledb_array__hosted_file_directory", (type(None), str)
)
if self.user_annotations__enable:
server_config = self.app_config.server_config
if not self.app__authentication_enable:
raise ConfigurationError("user annotations requires authentication to be enabled")
if not server_config.auth.is_valid_authentication_type():
auth_type = server_config.authentication__type
raise ConfigurationError(f"authentication method {auth_type} is not compatible with user annotations")
if self.user_annotations__type == "local_file_csv":
self.handle_local_file_csv_annotations()
elif self.user_annotations__type == "hosted_tiledb_array":
self.handle_hosted_tiledb_annotations()
else:
raise ConfigurationError('The only annotation type support is "local_file_csv" or "hosted_tiledb_array')
if self.user_annotations__ontology__enable or self.user_annotations__ontology__obo_location:
try:
self.user_annotations.load_ontology(self.user_annotations__ontology__obo_location)
except OntologyLoadFailure as e:
raise ConfigurationError("Unable to load ontology terms\n" + str(e))
else:
self.check_annotation_config_vars_not_set(context)
def handle_local_file_csv_annotations(self):
dirname = self.user_annotations__local_file_csv__directory
filename = self.user_annotations__local_file_csv__file
if filename is not None and dirname is not None:
raise ConfigurationError("'annotations-file' and 'annotations-dir' may not be used together.")
if filename is not None:
lf_name, lf_ext = splitext(filename)
if lf_ext and lf_ext != ".csv":
raise ConfigurationError(f"annotation file type must be .csv: {filename}")
if dirname is not None and not isdir(dirname):
try:
os.mkdir(dirname)
except OSError:
raise ConfigurationError("Unable to create directory specified by --annotations-dir")
self.user_annotations = AnnotationsLocalFile(dirname, filename)
# if the user has specified a fixed label file, go ahead and validate it
# so that we can remove errors early in the process.
server_config = self.app_config.server_config
if server_config.single_dataset__datapath and self.user_annotations__local_file_csv__file:
with server_config.matrix_data_cache_manager.data_adaptor(
self.tag, server_config.single_dataset__datapath, self.app_config
) as data_adaptor:
data_adaptor.check_new_labels(self.user_annotations.read_labels(data_adaptor))
def handle_hosted_tiledb_annotations(self):
self.validate_correct_type_of_configuration_attribute("user_annotations__hosted_tiledb_array__db_uri", str)
self.validate_correct_type_of_configuration_attribute(
"user_annotations__hosted_tiledb_array__hosted_file_directory", str
)
self.user_annotations = AnnotationsHostedTileDB(
directory_path=self.user_annotations__hosted_tiledb_array__hosted_file_directory,
db=DbUtils(self.user_annotations__hosted_tiledb_array__db_uri),
)
def check_annotation_config_vars_not_set(self, context):
if self.user_annotations__type is not None:
dirname = self.user_annotations__local_file_csv__directory
filename = self.user_annotations__local_file_csv__file
db_uri = self.user_annotations__hosted_tiledb_array__db_uri
hosted_file_dirname = self.user_annotations__hosted_tiledb_array__hosted_file_directory
if filename is not None:
context["messagefn"]("Warning: --annotations-file ignored as annotations are disabled.")
if dirname is not None:
context["messagefn"]("Warning: --annotations-dir ignored as annotations are disabled.")
if db_uri is not None:
context["messagefn"]("Warning: db_uri ignored as annotations are disabled.")
if hosted_file_dirname is not None:
context["messagefn"](
"Warning: hosted_file_directory for hosted_tiledb_array ignored as annotations are disabled."
)
if self.user_annotations__ontology__enable:
context["messagefn"]("Warning: --experimental-annotations-ontology ignored as annotations are disabled.")
if self.user_annotations__ontology__obo_location is not None:
context["messagefn"](
"Warning: --experimental-annotations-ontology-obo ignored as annotations are disabled."
)
def handle_embeddings(self):
self.validate_correct_type_of_configuration_attribute("embeddings__names", list)
self.validate_correct_type_of_configuration_attribute("embeddings__enable_reembedding", bool)
server_config = self.app_config.server_config
if self.embeddings__enable_reembedding:
if server_config.single_dataset__datapath:
matrix_data_loader = MatrixDataLoader(
server_config.single_dataset__datapath, app_config=self.app_config
)
if matrix_data_loader.matrix_data_type != MatrixDataType.H5AD:
raise ConfigurationError("enable-reembedding is only supported with H5AD files.")
if server_config.adaptor__anndata_adaptor__backed:
raise ConfigurationError("enable-reembedding is not supported when run in --backed mode.")
try:
get_scanpy_module()
except NotImplementedError:
# Todo add scanpy to requirements.txt and remove this check once re-embeddings is fully supported
raise ConfigurationError("Please install scanpy to enable UMAP re-embedding")
def handle_diffexp(self, context):
self.validate_correct_type_of_configuration_attribute("diffexp__enable", bool)
self.validate_correct_type_of_configuration_attribute("diffexp__lfc_cutoff", float)
self.validate_correct_type_of_configuration_attribute("diffexp__top_n", int)
server_config = self.app_config.server_config
if server_config.single_dataset__datapath:
with server_config.matrix_data_cache_manager.data_adaptor(
self.tag, server_config.single_dataset__datapath, self.app_config
) as data_adaptor:
if self.diffexp__enable and data_adaptor.parameters.get("diffexp_may_be_slow", False):
context["messagefn"](
"CAUTION: due to the size of your dataset, "
"running differential expression may take longer or fail."
)
-96
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@@ -1,96 +0,0 @@
import os
from server.common.config.base_config import BaseConfig
from server.common.errors import ConfigurationError
from server.common.config import get_secret_key
from server.common.errors import SecretKeyRetrievalError
from server.common.utils.type_conversion_utils import convert_string_to_value
class ExternalConfig(BaseConfig):
"""Manages the config attribute associated with external configuration sources, such as
environment variables or the AWS Secrets Manager."""
def __init__(self, app_config, default_config):
super().__init__(app_config, default_config)
try:
self.environment = default_config["environment"]
self.aws_secrets_manager__region = default_config["aws_secrets_manager"]["region"]
self.aws_secrets_manager__secrets = default_config["aws_secrets_manager"]["secrets"]
except KeyError as e:
raise ConfigurationError(f"Unexpected config: {str(e)}")
def complete_config(self, context):
self.handle_environment(context)
self.handle_aws_secrets_manager(context)
def handle_environment(self, context):
"""For each environment variable defined, get the value (if it is set),
and set the specified config parameter"""
self.validate_correct_type_of_configuration_attribute("environment", list)
for envdict in self.environment:
name = envdict.get("name")
if name is None:
raise ConfigurationError("environment: 'name' is missing")
required = envdict.get("required", False)
if type(required) != bool:
raise ConfigurationError("environment: 'required' must be a bool")
path = envdict.get("path")
if path is None:
raise ConfigurationError("environment: 'path' is missing")
value = os.environ.get(name)
if value is None:
if required:
raise ConfigurationError(f"required environment variable '{name}' not set")
else:
value = convert_string_to_value(value)
self.app_config.update_single_config_from_path_and_value(path, value)
def handle_aws_secrets_manager(self, context):
"""For each aws secret defined, get the key/values, and set the specified config parameter"""
self.validate_correct_type_of_configuration_attribute("aws_secrets_manager__region", (type(None), str))
self.validate_correct_type_of_configuration_attribute("aws_secrets_manager__secrets", list)
if not self.aws_secrets_manager__secrets:
return
self.validate_correct_type_of_configuration_attribute("aws_secrets_manager__region", str)
for secret in self.aws_secrets_manager__secrets:
secret_name = secret.get("name")
if secret_name is None:
raise ConfigurationError("aws_secrets_manager: 'name' is missing")
if not isinstance(secret_name, str):
raise ConfigurationError("aws_secrets_manager: 'name' must be a string")
try:
secret_dict = get_secret_key(self.aws_secrets_manager__region, secret_name)
except SecretKeyRetrievalError as e:
raise ConfigurationError(f"Unable to retrieve secret {secret_name}: {str(e)}")
values = secret.get("values")
if values is None:
raise ConfigurationError("aws_secrets_manager: 'values' is missing")
if not isinstance(values, list):
raise ConfigurationError("aws_secrets_manager: 'values' must be a list")
for value in values:
key = value.get("key")
if key is None:
raise ConfigurationError(f"missing 'key' in secret values: {secret_name}")
path = value.get("path")
if path is None:
raise ConfigurationError(f"missing 'path' in secret values: {secret_name}")
required = value.get("required", False)
if type(required) != bool:
raise ConfigurationError(f"wrong type for 'required' in secret values: {secret_name}")
secret_value = secret_dict.get(key)
if secret_value is None:
if required:
raise ConfigurationError(f"required secret '{secret_name}:{key}' not set")
else:
secret_value = convert_string_to_value(secret_value)
self.app_config.update_single_config_from_path_and_value(path, secret_value)
-387
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@@ -1,387 +0,0 @@
import os
import sys
import warnings
from os.path import basename
from urllib.parse import urlparse, quote_plus
from server.auth.auth import AuthTypeFactory
from server.common.config.base_config import BaseConfig
from server.common.config import DEFAULT_SERVER_PORT, BIG_FILE_SIZE_THRESHOLD
from server.common.errors import ConfigurationError, DatasetAccessError
from server.common.data_locator import discover_s3_region_name
from server.common.utils.utils import is_port_available, find_available_port, custom_format_warning
from server.compute import diffexp_cxg as diffexp_tiledb
from server.data_common.matrix_loader import MatrixDataCacheManager, MatrixDataLoader, MatrixDataType
class ServerConfig(BaseConfig):
"""Manages the config attribute associated with the server."""
def __init__(self, app_config, default_config):
dictval_cases = [
("app", "csp_directives"),
("authentication", "params_oauth", "cookie"),
("authentication", "params_oauth", "jwt_decode_options"),
("adaptor", "cxg_adaptor", "tiledb_ctx"),
("multi_dataset", "dataroot"),
]
super().__init__(app_config, default_config, dictval_cases)
try:
self.app__verbose = default_config["app"]["verbose"]
self.app__debug = default_config["app"]["debug"]
self.app__host = default_config["app"]["host"]
self.app__port = default_config["app"]["port"]
self.app__open_browser = default_config["app"]["open_browser"]
self.app__force_https = default_config["app"]["force_https"]
self.app__flask_secret_key = default_config["app"]["flask_secret_key"]
self.app__generate_cache_control_headers = default_config["app"]["generate_cache_control_headers"]
self.app__server_timing_headers = default_config["app"]["server_timing_headers"]
self.app__csp_directives = default_config["app"]["csp_directives"]
self.app__api_base_url = default_config["app"]["api_base_url"]
self.app__web_base_url = default_config["app"]["web_base_url"]
self.authentication__type = default_config["authentication"]["type"]
self.authentication__insecure_test_environment = default_config["authentication"][
"insecure_test_environment"
]
self.authentication__params_oauth__oauth_api_base_url = default_config["authentication"]["params_oauth"][
"oauth_api_base_url"
]
self.authentication__params_oauth__client_id = default_config["authentication"]["params_oauth"]["client_id"]
self.authentication__params_oauth__client_secret = default_config["authentication"]["params_oauth"][
"client_secret"
]
self.authentication__params_oauth__jwt_decode_options = default_config["authentication"]["params_oauth"][
"jwt_decode_options"
]
self.authentication__params_oauth__session_cookie = default_config["authentication"]["params_oauth"][
"session_cookie"
]
self.authentication__params_oauth__cookie = default_config["authentication"]["params_oauth"]["cookie"]
self.multi_dataset__dataroot = default_config["multi_dataset"]["dataroot"]
self.multi_dataset__index = default_config["multi_dataset"]["index"]
self.multi_dataset__allowed_matrix_types = default_config["multi_dataset"]["allowed_matrix_types"]
self.multi_dataset__matrix_cache__max_datasets = default_config["multi_dataset"]["matrix_cache"][
"max_datasets"
]
self.multi_dataset__matrix_cache__timelimit_s = default_config["multi_dataset"]["matrix_cache"][
"timelimit_s"
]
self.single_dataset__datapath = default_config["single_dataset"]["datapath"]
self.single_dataset__obs_names = default_config["single_dataset"]["obs_names"]
self.single_dataset__var_names = default_config["single_dataset"]["var_names"]
self.single_dataset__about = default_config["single_dataset"]["about"]
self.single_dataset__title = default_config["single_dataset"]["title"]
self.diffexp__alg_cxg__max_workers = default_config["diffexp"]["alg_cxg"]["max_workers"]
self.diffexp__alg_cxg__cpu_multiplier = default_config["diffexp"]["alg_cxg"]["cpu_multiplier"]
self.diffexp__alg_cxg__target_workunit = default_config["diffexp"]["alg_cxg"]["target_workunit"]
self.data_locator__s3__region_name = default_config["data_locator"]["s3"]["region_name"]
self.adaptor__cxg_adaptor__tiledb_ctx = default_config["adaptor"]["cxg_adaptor"]["tiledb_ctx"]
self.adaptor__anndata_adaptor__backed = default_config["adaptor"]["anndata_adaptor"]["backed"]
self.limits__diffexp_cellcount_max = default_config["limits"]["diffexp_cellcount_max"]
self.limits__column_request_max = default_config["limits"]["column_request_max"]
except KeyError as e:
raise ConfigurationError(f"Unexpected config: {str(e)}")
# The matrix data cache manager is created during the complete_config and stored here.
self.matrix_data_cache_manager = None
# The authentication object
self.auth = None
def complete_config(self, context):
self.handle_app(context)
self.handle_data_source()
self.handle_authentication()
self.handle_data_locator()
self.handle_adaptor() # may depend on data_locator
self.handle_single_dataset(context) # may depend on adaptor
self.handle_multi_dataset() # may depend on adaptor
self.handle_diffexp()
self.handle_limits()
self.check_config()
def handle_app(self, context):
self.validate_correct_type_of_configuration_attribute("app__verbose", bool)
self.validate_correct_type_of_configuration_attribute("app__debug", bool)
self.validate_correct_type_of_configuration_attribute("app__host", str)
self.validate_correct_type_of_configuration_attribute("app__port", (type(None), int))
self.validate_correct_type_of_configuration_attribute("app__open_browser", bool)
self.validate_correct_type_of_configuration_attribute("app__force_https", bool)
self.validate_correct_type_of_configuration_attribute("app__flask_secret_key", str)
self.validate_correct_type_of_configuration_attribute("app__generate_cache_control_headers", bool)
self.validate_correct_type_of_configuration_attribute("app__server_timing_headers", bool)
self.validate_correct_type_of_configuration_attribute("app__csp_directives", (type(None), dict))
self.validate_correct_type_of_configuration_attribute("app__api_base_url", (type(None), str))
self.validate_correct_type_of_configuration_attribute("app__web_base_url", (type(None), str))
if self.app__port:
try:
if not is_port_available(self.app__host, self.app__port):
raise ConfigurationError(
f"The port selected {self.app__port} is in use, please configure an open port."
)
except OverflowError:
raise ConfigurationError(f"Invalid port: {self.app__port}")
else:
try:
default_server_port = int(os.environ.get("CXG_SERVER_PORT", DEFAULT_SERVER_PORT))
except ValueError:
raise ConfigurationError(
"Invalid port from environment variable CXG_SERVER_PORT: " + os.environ.get("CXG_SERVER_PORT")
)
try:
self.app__port = find_available_port(self.app__host, default_server_port)
except OverflowError:
raise ConfigurationError(f"Invalid port: {default_server_port}")
if self.app__debug:
context["messagefn"]("in debug mode, setting verbose=True and open_browser=False")
self.app__verbose = True
self.app__open_browser = False
else:
warnings.formatwarning = custom_format_warning
if not self.app__verbose:
sys.tracebacklimit = 0
# CSP Directives are a dict of string: list(string) or string: string
if self.app__csp_directives is not None:
for k, v in self.app__csp_directives.items():
if not isinstance(k, str):
raise ConfigurationError("CSP directive names must be a string.")
if isinstance(v, list):
for policy in v:
if not isinstance(policy, str):
raise ConfigurationError("CSP directive value must be a string or list of strings.")
elif not isinstance(v, str):
raise ConfigurationError("CSP directive value must be a string or list of strings.")
if self.app__web_base_url is None:
self.app__web_base_url = self.app__api_base_url
def handle_authentication(self):
self.validate_correct_type_of_configuration_attribute("authentication__type", (type(None), str))
self.validate_correct_type_of_configuration_attribute("authentication__insecure_test_environment", bool)
if self.authentication__type == "test" and not self.authentication__insecure_test_environment:
raise ConfigurationError("Test auth can only be used in an insecure test environment")
# oauth
ptypes = str if self.authentication__type == "oauth" else (type(None), str)
self.validate_correct_type_of_configuration_attribute(
"authentication__params_oauth__oauth_api_base_url", ptypes
)
self.validate_correct_type_of_configuration_attribute("authentication__params_oauth__client_id", ptypes)
self.validate_correct_type_of_configuration_attribute("authentication__params_oauth__client_secret", ptypes)
self.validate_correct_type_of_configuration_attribute(
"authentication__params_oauth__jwt_decode_options", (type(None), dict)
)
self.validate_correct_type_of_configuration_attribute("authentication__params_oauth__session_cookie", bool)
if self.authentication__params_oauth__session_cookie:
self.validate_correct_type_of_configuration_attribute(
"authentication__params_oauth__cookie", (type(None), dict)
)
else:
self.validate_correct_type_of_configuration_attribute("authentication__params_oauth__cookie", dict)
self.auth = AuthTypeFactory.create(self.authentication__type, self)
if self.auth is None:
raise ConfigurationError(f"Unknown authentication type: {self.authentication__type}")
def handle_data_locator(self):
self.validate_correct_type_of_configuration_attribute("data_locator__s3__region_name", (type(None), bool, str))
if self.data_locator__s3__region_name is True:
path = self.single_dataset__datapath or self.multi_dataset__dataroot
if type(path) == dict:
# if multi_dataset__dataroot is a dict, then use the first key
# that is in s3. NOTE: it is not supported to have dataroots
# in different regions.
paths = [val.get("dataroot") for val in path.values()]
for path in paths:
if path.startswith("s3://"):
break
if path.startswith("s3://"):
region_name = discover_s3_region_name(path)
if region_name is None:
raise ConfigurationError(f"Unable to discover s3 region name from {path}")
else:
region_name = None
self.data_locator__s3__region_name = region_name
def handle_data_source(self):
self.validate_correct_type_of_configuration_attribute("single_dataset__datapath", (str, type(None)))
self.validate_correct_type_of_configuration_attribute("multi_dataset__dataroot", (type(None), dict, str))
if self.single_dataset__datapath and self.multi_dataset__dataroot:
raise ConfigurationError(
"You must supply either a datapath (for single datasets) or a dataroot (for multidatasets). Not both"
)
if self.single_dataset__datapath is None and self.multi_dataset__dataroot is None:
raise ConfigurationError("You must specify a datapath for a single dataset or a dataroot for multidatasets")
def handle_single_dataset(self, context):
self.validate_correct_type_of_configuration_attribute("single_dataset__datapath", (str, type(None)))
self.validate_correct_type_of_configuration_attribute("single_dataset__title", (str, type(None)))
self.validate_correct_type_of_configuration_attribute("single_dataset__about", (str, type(None)))
self.validate_correct_type_of_configuration_attribute("single_dataset__obs_names", (str, type(None)))
self.validate_correct_type_of_configuration_attribute("single_dataset__var_names", (str, type(None)))
if self.single_dataset__datapath is None:
return
# create the matrix data cache manager:
if self.matrix_data_cache_manager is None:
self.matrix_data_cache_manager = MatrixDataCacheManager(max_cached=1, timelimit_s=None)
# preload this data set
matrix_data_loader = MatrixDataLoader(self.single_dataset__datapath, app_config=self.app_config)
try:
matrix_data_loader.pre_load_validation()
except DatasetAccessError as e:
raise ConfigurationError(str(e))
file_size = matrix_data_loader.file_size()
file_basename = basename(self.single_dataset__datapath)
if file_size > BIG_FILE_SIZE_THRESHOLD:
context["messagefn"](f"Loading data from {file_basename}, this may take a while...")
else:
context["messagefn"](f"Loading data from {file_basename}.")
if self.single_dataset__about:
def url_check(url):
try:
result = urlparse(url)
if all([result.scheme, result.netloc]):
return True
else:
return False
except ValueError:
return False
if not url_check(self.single_dataset__about):
raise ConfigurationError(
"Must provide an absolute URL for --about. (Example format: http://example.com)"
)
def handle_multi_dataset(self):
self.validate_correct_type_of_configuration_attribute("multi_dataset__dataroot", (type(None), dict, str))
self.validate_correct_type_of_configuration_attribute("multi_dataset__index", (type(None), bool, str))
self.validate_correct_type_of_configuration_attribute("multi_dataset__allowed_matrix_types", list)
self.validate_correct_type_of_configuration_attribute("multi_dataset__matrix_cache__max_datasets", int)
self.validate_correct_type_of_configuration_attribute(
"multi_dataset__matrix_cache__timelimit_s", (type(None), int, float)
)
if self.multi_dataset__dataroot is None:
return
if type(self.multi_dataset__dataroot) == str:
default_dict = dict(base_url="d", dataroot=self.multi_dataset__dataroot)
self.multi_dataset__dataroot = dict(d=default_dict)
for tag, dataroot_dict in self.multi_dataset__dataroot.items():
if "base_url" not in dataroot_dict:
raise ConfigurationError(f"error in multi_dataset__dataroot: missing base_url for tag {tag}")
if "dataroot" not in dataroot_dict:
raise ConfigurationError(f"error in multi_dataset__dataroot: missing dataroot, for tag {tag}")
base_url = dataroot_dict["base_url"]
# sanity check for well formed base urls
bad = False
if type(base_url) != str:
bad = True
elif os.path.normpath(base_url) != base_url:
bad = True
else:
base_url_parts = base_url.split("/")
if [quote_plus(part) for part in base_url_parts] != base_url_parts:
bad = True
if ".." in base_url_parts:
bad = True
if bad:
raise ConfigurationError(f"error in multi_dataset__dataroot base_url {base_url} for tag {tag}")
# verify all the base_urls are unique
base_urls = [d["base_url"] for d in self.multi_dataset__dataroot.values()]
if len(base_urls) > len(set(base_urls)):
raise ConfigurationError("error in multi_dataset__dataroot: base_urls must be unique")
# error checking
for mtype in self.multi_dataset__allowed_matrix_types:
try:
MatrixDataType(mtype)
except ValueError:
raise ConfigurationError(f'Invalid matrix type in "allowed_matrix_types": {mtype}')
# create the matrix data cache manager:
if self.matrix_data_cache_manager is None:
self.matrix_data_cache_manager = MatrixDataCacheManager(
max_cached=self.multi_dataset__matrix_cache__max_datasets,
timelimit_s=self.multi_dataset__matrix_cache__timelimit_s,
)
def handle_diffexp(self):
self.validate_correct_type_of_configuration_attribute("diffexp__alg_cxg__max_workers", (str, int))
self.validate_correct_type_of_configuration_attribute("diffexp__alg_cxg__cpu_multiplier", int)
self.validate_correct_type_of_configuration_attribute("diffexp__alg_cxg__target_workunit", int)
max_workers = self.diffexp__alg_cxg__max_workers
cpu_multiplier = self.diffexp__alg_cxg__cpu_multiplier
cpu_count = os.cpu_count()
max_workers = min(max_workers, cpu_multiplier * cpu_count)
diffexp_tiledb.set_config(max_workers, self.diffexp__alg_cxg__target_workunit)
def handle_adaptor(self):
# cxg
self.validate_correct_type_of_configuration_attribute("adaptor__cxg_adaptor__tiledb_ctx", dict)
regionkey = "vfs.s3.region"
if regionkey not in self.adaptor__cxg_adaptor__tiledb_ctx:
if type(self.data_locator__s3__region_name) == str:
self.adaptor__cxg_adaptor__tiledb_ctx[regionkey] = self.data_locator__s3__region_name
from server.data_cxg.cxg_adaptor import CxgAdaptor
CxgAdaptor.set_tiledb_context(self.adaptor__cxg_adaptor__tiledb_ctx)
# anndata
self.validate_correct_type_of_configuration_attribute("adaptor__anndata_adaptor__backed", bool)
def handle_limits(self):
self.validate_correct_type_of_configuration_attribute("limits__diffexp_cellcount_max", (type(None), int))
self.validate_correct_type_of_configuration_attribute("limits__column_request_max", (type(None), int))
def exceeds_limit(self, limit_name, value):
limit_value = getattr(self, "limits__" + limit_name, None)
if limit_value is None: # disabled
return False
return value > limit_value
def get_api_base_url(self):
if self.app__api_base_url == "local":
return f"http://{self.app__host}:{self.app__port}"
if self.app__api_base_url and self.app__api_base_url.endswith("/"):
return self.app__api_base_url[:-1]
return self.app__api_base_url
def get_web_base_url(self):
if self.app__web_base_url == "local":
return f"http://{self.app__host}:{self.app__port}"
if self.app__web_base_url is None:
return self.get_api_base_url()
if self.app__web_base_url.endswith("/"):
return self.app__web_base_url[:-1]
return self.app__web_base_url
-30
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@@ -1,30 +0,0 @@
from enum import Enum
class AugmentedEnum(Enum):
def __hash__(self):
return self.value.__hash__()
def __eq__(self, other):
if isinstance(other, type(self)) or isinstance(other, str):
return self.value == other
return False
def __str__(self) -> str:
return self.value
class Axis(AugmentedEnum):
OBS = "obs"
VAR = "var"
class DiffExpMode(AugmentedEnum):
TOP_N = "topN"
VAR_FILTER = "varFilter"
JSON_NaN_to_num_warning_msg = "JSON encoding failure - please verify all data are finite values (no NaN or Infinities)"
REACTIVE_LIMIT = 1_000_000
MAX_LAYOUTS = 30
-78
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@@ -1,78 +0,0 @@
"""
Corpora schema conventions support. Helper functions for reading.
https://github.com/chanzuckerberg/corpora-data-portal/blob/main/backend/schema/corpora_schema.md
https://github.com/chanzuckerberg/corpora-data-portal/blob/main/backend/schema/corpora_schema_h5ad_implementation.md
"""
import collections
import json
from server.cli.upgrade import validate_version_str
from server.common.utils.corpora_constants import CorporaConstants
def corpora_get_versions_from_anndata(adata):
"""
Given an AnnData object, return:
* None - if not a Corpora object
* [ corpora_schema_version, corpora_encoding_version ] - if a Corpora object
Implements the identification protocol defined in the specification.
"""
# per Corpora AnnData spec, this is a corpora file if the following is true
if "version" not in adata.uns_keys():
return None
version = adata.uns["version"]
if not isinstance(version, collections.abc.Mapping) or "corpora_schema_version" not in version:
return None
corpora_schema_version = version.get("corpora_schema_version")
corpora_encoding_version = version.get("corpora_encoding_version")
# TODO: spec says these must be SEMVER values, so check.
if validate_version_str(corpora_schema_version) and validate_version_str(corpora_encoding_version):
return [corpora_schema_version, corpora_encoding_version]
def corpora_is_version_supported(corpora_schema_version, corpora_encoding_version):
return (
corpora_schema_version
and corpora_encoding_version
and corpora_schema_version.startswith("1.")
and corpora_encoding_version.startswith("0.1.")
)
def corpora_get_props_from_anndata(adata):
"""
Get Corpora dataset properties from an AnnData
"""
versions = corpora_get_versions_from_anndata(adata)
if versions is None:
return None
[corpora_schema_version, corpora_encoding_version] = versions
version_is_supported = corpora_is_version_supported(corpora_schema_version, corpora_encoding_version)
if not version_is_supported:
raise ValueError("Unsupported Corpora schema version")
corpora_props = {}
for key in CorporaConstants.REQUIRED_SIMPLE_METADATA_FIELDS:
if key not in adata.uns:
raise KeyError(f"missing Corpora schema field {key}")
corpora_props[key] = adata.uns[key]
for key in CorporaConstants.OPTIONAL_JSON_ENCODED_METADATA_FIELD:
if key not in adata.uns:
continue
try:
corpora_props[key] = json.loads(adata.uns[key])
except json.JSONDecodeError:
raise json.JSONDecodeError(f"Corpora schema field {key} is expected to be a valid JSON string")
for key in CorporaConstants.OPTIONAL_SIMPLE_METADATA_FIELDS:
if key in adata.uns:
corpora_props[key] = adata.uns[key]
return corpora_props
-154
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@@ -1,154 +0,0 @@
import os
import tempfile
import fsspec
from datetime import datetime
import boto3
import botocore
from urllib.parse import urlparse
class DataLocator:
"""
DataLocator is a simple wrapper around fsspec functionality, and provides a
set of functions to encapsulate a data location (URI or path), interogate
metadata about the object at that location (size, existance, etc) and
access the underlying data.
https://filesystem-spec.readthedocs.io/en/latest/index.html
Example:
dl = DataLocator("/tmp/foo.h5ad")
if dl.exists():
print(dl.size())
with dl.open() as f:
thecontents = f.read()
DataLocator will accept a URI or native path. Error handling is as defined
in fsspec.
"""
def __init__(self, uri_or_path, region_name=None):
if isinstance(uri_or_path, DataLocator):
locator = uri_or_path
self.uri_or_path = locator.uri_or_path
self.protocol = locator.protocol
self.path = locator.path
self.cname = locator.cname
else:
self.uri_or_path = uri_or_path
self.protocol, self.path = DataLocator._get_protocol_and_path(uri_or_path)
# work-around for LocalFileSystem not treating file: and None as the same scheme/protocol
self.cname = self.path if self.protocol == "file" else self.uri_or_path
# fsspec.filesystem will throw RuntimeError if the protocol is unsupported
if self.protocol == "s3":
if region_name:
config_kwargs = dict(region_name=region_name)
self.fs = fsspec.filesystem(self.protocol, listings_expiry_time=30, config_kwargs=config_kwargs)
else:
self.fs = fsspec.filesystem(self.protocol, listings_expiry_time=30)
else:
self.fs = fsspec.filesystem(self.protocol)
def __repr__(self):
return f"DataLocator(protocol={self.protocol}, cname={self.cname}, "
f"path={self.path}, uri_or_path={self.uri_or_path})"
@staticmethod
def _get_protocol_and_path(uri_or_path):
if "://" in uri_or_path:
protocol, path = uri_or_path.split("://", 1)
# windows!!! Ignore single letter drive identifiers,
# eg, G:\foo.txt
if len(protocol) > 1:
return protocol, path
return None, uri_or_path
def exists(self):
return self.fs.exists(self.cname)
def size(self):
return self.fs.size(self.cname)
def lastmodtime(self):
""" return datetime object representing last modification time, or None if unavailable """
info = self.fs.info(self.cname)
if self.islocal() and info is not None:
return datetime.fromtimestamp(info["mtime"])
else:
return getattr(info, "LastModified", None)
def abspath(self):
"""
return the absolute path for the locator - only really does something
for file: protocol, as all others are already absolute
"""
if self.islocal():
return os.path.abspath(self.path)
else:
return self.uri_or_path
def isfile(self):
return self.fs.isfile(self.cname)
def open(self, *args):
return self.fs.open(self.uri_or_path, *args)
def islocal(self):
return self.protocol is None or self.protocol == "file"
def local_handle(self):
if self.islocal():
return LocalFilePath(self.path)
# if not local, create a tmp file system object to contain the data,
# and clean it up when done. If the path has a suffix/extension,
# do our best to create a file with the same.
ext = os.path.splitext(self.path)
suffix = None if ext[1] == "" else ext[1]
with self.open() as src, tempfile.NamedTemporaryFile(prefix="cellxgene_", suffix=suffix, delete=False) as tmp:
tmp.write(src.read())
tmp.close()
src.close()
tmp_path = tmp.name
return LocalFilePath(tmp_path, delete=True)
def ls(self):
paths = self.fs.ls(self.uri_or_path)
return [os.path.basename(p) for p in paths]
class LocalFilePath:
def __init__(self, tmp_path, delete=False):
self.tmp_path = tmp_path
self.delete = delete
def __enter__(self):
return self.tmp_path
def __exit__(self, *args):
if self.delete:
os.unlink(self.tmp_path)
def discover_s3_region_name(uri):
"""If this is an s3 protocol, discover and return the (aws) region name.
If a return name could not be discovered, or if the uri is not an s3 protocol, return None."""
protocol, _ = DataLocator._get_protocol_and_path(uri)
if protocol == "s3":
bucket = urlparse(uri).netloc
client = boto3.client("s3")
try:
res = client.head_bucket(Bucket=bucket)
except botocore.exceptions.ClientError:
return None
region = res.get("ResponseMetadata", {}).get("HTTPHeaders", {}).get("x-amz-bucket-region")
if region:
return region
else:
return None
return None
-57
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@@ -1,57 +0,0 @@
from http import HTTPStatus
class CellxgeneException(Exception):
"""Base class for cellxgene exceptions"""
def __init__(self, message):
self.message = message
super().__init__(message)
class RequestException(CellxgeneException):
"""Baseclass for exceptions that can be raised from a request."""
# The default status code is 400 (Bad Request)
default_status_code = HTTPStatus.BAD_REQUEST
def __init__(self, message, status_code=None):
super().__init__(message)
self.status_code = status_code or self.default_status_code
def define_exception(name, doc):
globals()[name] = type(name, (CellxgeneException,), dict(__doc__=doc))
def define_request_exception(name, doc, default_status_code=HTTPStatus.BAD_REQUEST):
globals()[name] = type(name, (RequestException,), dict(__doc__=doc, default_status_code=default_status_code))
define_request_exception("FilterError", "Raised when filter is malformed")
define_request_exception("JSONEncodingValueError", "Raised when data cannot be encoded into json")
define_request_exception("MimeTypeError", "Raised when incompatible MIME type selected")
define_request_exception("DatasetAccessError", "Raised when file loaded into a DataAdaptor is misformatted")
define_request_exception("DisabledFeatureError", "Raised when an attempt to use a disabled feature occurs")
define_request_exception("AnnotationsError", "Raised when an attempt to use the annotations feature fails")
define_request_exception(
"ComputeError",
"Raised when an error occurs during a compute algorithm (such as diffexp)",
HTTPStatus.INTERNAL_SERVER_ERROR,
)
define_request_exception("ExceedsLimitError", "Raised when an HTTP request exceeds a limit/quota")
define_request_exception("ColorFormatException", "Raised when color helper functions encounter an unknown color format")
define_request_exception(
"AuthenticationError", "Raised when there is an authentication error", default_status_code=HTTPStatus.UNAUTHORIZED
)
define_request_exception(
"AnnotationCategoryNameError",
"Raised when an annotation category name cant be saved",
default_status_code=HTTPStatus.UNPROCESSABLE_ENTITY,
)
define_exception("OntologyLoadFailure", "Raised when reading the ontology file fails")
define_exception("ConfigurationError", "Raised when checking configuration errors")
define_exception("PrepareError", "Raised when data is misprepared")
define_exception("SecretKeyRetrievalError", "Raised when get_secret_key from AWS fails")
-38
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@@ -1,38 +0,0 @@
from http import HTTPStatus
from flask import make_response, jsonify
from server import __version__ as cellxgene_version
from server.common.data_locator import DataLocator
def _is_accessible(path, config):
if path is None:
return True
try:
dl = DataLocator(path, region_name=config.data_locator__s3__region_name)
return dl.exists()
except RuntimeError:
return False
def health_check(config):
"""
simple health check - return HTTP response.
See https://tools.ietf.org/id/draft-inadarei-api-health-check-01.html
"""
health = {"status": None, "version": "1", "releaseID": cellxgene_version}
checks = False
server_config = config.server_config
if config.is_multi_dataset():
dataroots = [datapath_dict["dataroot"] for datapath_dict in server_config.multi_dataset__dataroot.values()]
checks = all([_is_accessible(dataroot, server_config) for dataroot in dataroots])
else:
checks = _is_accessible(server_config.single_dataset__datapath, server_config)
health["status"] = "pass" if checks else "fail"
code = HTTPStatus.OK if health["status"] == "pass" else HTTPStatus.BAD_REQUEST
response = make_response(jsonify(health), code)
response.headers["Content-Type"] = "application/health+json"
return response
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@@ -1,71 +0,0 @@
import threading
from collections.abc import MutableMapping
class ImmutableKVCache(MutableMapping):
"""
Guarantees that the factory will be called for each key once, and
only once.
"""
def __init__(self, factory):
self.factory = factory # user-provided factory function
self.lock = threading.Lock() # guards factory_calls
self.factory_calls = {} # per-key factory condition variables
self.cache = {} # result cache, indexed by key
super().__init__()
def __getitem__(self, key):
if key in self.cache:
return self.cache[key]
# we need to call factory. First grab the main lock and the per-key CV.
factory_calls = None
creation_thr = False
with self.lock:
if key in self.cache:
return self.cache[key]
if key not in self.factory_calls:
creation_thr = True
self.factory_calls[key] = {"cv": threading.Condition(), "is_done": False, "error": None}
factory_calls = self.factory_calls[key]
# with the CV, create the value (or wait for it to be created)
cv = factory_calls["cv"]
with cv:
if creation_thr:
try:
self.cache[key] = self.factory(key)
except Exception as e:
factory_calls["error"] = e
factory_calls["is_done"] = True
cv.notify_all()
else:
""" wait for the value to be available """
while not factory_calls["is_done"]:
cv.wait()
with self.lock:
if key in self.factory_calls:
del self.factory_calls[key]
return self.cache[key]
def __iter__(self):
""" weak iter, don't call factory """
return self.cache.__iter__()
def __len__(self):
return self.cache.__len__()
def __contains__(self, key):
""" weak contain - don't call factory """
return self.cache.__contains__(key)
def __delitem__(self, key):
del self.cache[key]
def __setitem__(self, key, value):
""" unsupported """
raise NotImplementedError
-330
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@@ -1,330 +0,0 @@
import copy
import logging
import sys
from http import HTTPStatus
import zlib
from flask import make_response, jsonify, current_app, abort
from werkzeug.urls import url_unquote
from server.common.config.client_config import get_client_config, get_client_userinfo
from server.common.constants import Axis, DiffExpMode, JSON_NaN_to_num_warning_msg
from server.common.errors import (
FilterError,
JSONEncodingValueError,
PrepareError,
DisabledFeatureError,
ExceedsLimitError,
DatasetAccessError,
ColorFormatException,
)
import json
from server.data_common.fbs.matrix import decode_matrix_fbs
def abort_and_log(code, logmsg, loglevel=logging.DEBUG, include_exc_info=False):
"""
Log the message, then abort with HTTP code. If include_exc_info is true,
also include current exception via sys.exc_info().
"""
if include_exc_info:
exc_info = sys.exc_info()
else:
exc_info = False
current_app.logger.log(loglevel, logmsg, exc_info=exc_info)
# Do NOT send log message to HTTP response.
return abort(code)
def _query_parameter_to_filter(args):
"""
Convert an annotation value filter, if present in the query args,
into the standard dict filter format used by internal code.
Query param filters look like: <axis>:name=value, where value
may be one of:
- a range, min,max, where either may be an open range by using an asterisc, eg, 10,*
- a value
Eg,
...?tissue=lung&obs:tissue=heart&obs:num_reads=1000,*
"""
filters = {
"obs": {},
"var": {},
}
# args has already been url-unquoted once. We assume double escaping
# on name and value.
try:
for key, value in args.items(multi=True):
axis, name = key.split(":")
if axis not in ("obs", "var"):
raise FilterError("unknown filter axis")
name = url_unquote(name)
current = filters[axis].setdefault(name, {"name": name})
val_split = value.split(",")
if len(val_split) == 1:
if "min" in current or "max" in current:
raise FilterError("do not mix range and value filters")
value = url_unquote(value)
values = current.setdefault("values", [])
values.append(value)
elif len(val_split) == 2:
if len(current) > 1:
raise FilterError("duplicate range specification")
min = url_unquote(val_split[0])
max = url_unquote(val_split[1])
if min != "*":
current["min"] = float(min)
if max != "*":
current["max"] = float(max)
if len(current) < 2:
raise FilterError("must specify at least min or max in range filter")
else:
raise FilterError("badly formated filter value")
except ValueError as e:
raise FilterError(str(e))
result = {}
for axis in ("obs", "var"):
axis_filter = filters[axis]
if len(axis_filter) > 0:
result[axis] = {"annotation_value": [val for val in axis_filter.values()]}
return result
def schema_get_helper(data_adaptor):
"""helper function to gather the schema from the data source and annotations"""
schema = data_adaptor.get_schema()
schema = copy.deepcopy(schema)
# add label obs annotations as needed
annotations = data_adaptor.dataset_config.user_annotations
if annotations is not None:
label_schema = annotations.get_schema(data_adaptor)
schema["annotations"]["obs"]["columns"].extend(label_schema)
return schema
def schema_get(data_adaptor):
schema = schema_get_helper(data_adaptor)
return make_response(jsonify({"schema": schema}), HTTPStatus.OK)
def config_get(app_config, data_adaptor):
config = get_client_config(app_config, data_adaptor)
return make_response(jsonify(config), HTTPStatus.OK)
def userinfo_get(app_config, data_adaptor):
config = get_client_userinfo(app_config, data_adaptor)
return make_response(jsonify(config), HTTPStatus.OK)
def annotations_obs_get(request, data_adaptor):
fields = request.args.getlist("annotation-name", None)
num_columns_requested = len(data_adaptor.get_obs_keys()) if len(fields) == 0 else len(fields)
if data_adaptor.server_config.exceeds_limit("column_request_max", num_columns_requested):
return abort(HTTPStatus.BAD_REQUEST)
preferred_mimetype = request.accept_mimetypes.best_match(["application/octet-stream"])
if preferred_mimetype != "application/octet-stream":
return abort(HTTPStatus.NOT_ACCEPTABLE)
try:
labels = None
annotations = data_adaptor.dataset_config.user_annotations
if annotations:
labels = annotations.read_labels(data_adaptor)
fbs = data_adaptor.annotation_to_fbs_matrix(Axis.OBS, fields, labels)
return make_response(fbs, HTTPStatus.OK, {"Content-Type": "application/octet-stream"})
except KeyError as e:
return abort_and_log(HTTPStatus.BAD_REQUEST, str(e), include_exc_info=True)
def annotations_put_fbs_helper(data_adaptor, fbs):
"""helper function to write annotations from fbs"""
annotations = data_adaptor.dataset_config.user_annotations
if annotations is None:
raise DisabledFeatureError("Writable annotations are not enabled")
new_label_df = decode_matrix_fbs(fbs)
if not new_label_df.empty:
new_label_df = data_adaptor.check_new_labels(new_label_df)
annotations.write_labels(new_label_df, data_adaptor)
def inflate(data):
return zlib.decompress(data)
def annotations_obs_put(request, data_adaptor):
annotations = data_adaptor.dataset_config.user_annotations
if annotations is None:
return abort(HTTPStatus.NOT_IMPLEMENTED)
anno_collection = request.args.get("annotation-collection-name", default=None)
fbs = inflate(request.get_data())
if anno_collection is not None:
if not annotations.is_safe_collection_name(anno_collection):
return abort(HTTPStatus.BAD_REQUEST, "Bad annotation collection name")
annotations.set_collection(anno_collection)
try:
annotations_put_fbs_helper(data_adaptor, fbs)
res = json.dumps({"status": "OK"})
return make_response(res, HTTPStatus.OK, {"Content-Type": "application/json"})
except (ValueError, DisabledFeatureError, KeyError) as e:
return abort_and_log(HTTPStatus.BAD_REQUEST, str(e), include_exc_info=True)
def annotations_var_get(request, data_adaptor):
fields = request.args.getlist("annotation-name", None)
num_columns_requested = len(data_adaptor.get_var_keys()) if len(fields) == 0 else len(fields)
if data_adaptor.server_config.exceeds_limit("column_request_max", num_columns_requested):
return abort(HTTPStatus.BAD_REQUEST)
preferred_mimetype = request.accept_mimetypes.best_match(["application/octet-stream"])
if preferred_mimetype != "application/octet-stream":
return abort(HTTPStatus.NOT_ACCEPTABLE)
try:
labels = None
annotations = data_adaptor.dataset_config.user_annotations
if annotations is not None:
labels = annotations.read_labels(data_adaptor)
return make_response(
data_adaptor.annotation_to_fbs_matrix(Axis.VAR, fields, labels),
HTTPStatus.OK,
{"Content-Type": "application/octet-stream"},
)
except KeyError as e:
return abort_and_log(HTTPStatus.BAD_REQUEST, str(e), include_exc_info=True)
def data_var_put(request, data_adaptor):
preferred_mimetype = request.accept_mimetypes.best_match(["application/octet-stream"])
if preferred_mimetype != "application/octet-stream":
return abort(HTTPStatus.NOT_ACCEPTABLE)
filter_json = request.get_json()
filter = filter_json["filter"] if filter_json else None
try:
return make_response(
data_adaptor.data_frame_to_fbs_matrix(filter, axis=Axis.VAR),
HTTPStatus.OK,
{"Content-Type": "application/octet-stream"},
)
except (FilterError, ValueError, ExceedsLimitError) as e:
return abort_and_log(HTTPStatus.BAD_REQUEST, str(e), include_exc_info=True)
def data_var_get(request, data_adaptor):
preferred_mimetype = request.accept_mimetypes.best_match(["application/octet-stream"])
if preferred_mimetype != "application/octet-stream":
return abort(HTTPStatus.NOT_ACCEPTABLE)
try:
filter = _query_parameter_to_filter(request.args)
return make_response(
data_adaptor.data_frame_to_fbs_matrix(filter, axis=Axis.VAR),
HTTPStatus.OK,
{"Content-Type": "application/octet-stream"},
)
except (FilterError, ValueError, ExceedsLimitError) as e:
return abort_and_log(HTTPStatus.BAD_REQUEST, str(e), include_exc_info=True)
def colors_get(data_adaptor):
if not data_adaptor.dataset_config.presentation__custom_colors:
return make_response(jsonify({}), HTTPStatus.OK)
try:
return make_response(jsonify(data_adaptor.get_colors()), HTTPStatus.OK)
except ColorFormatException as e:
return abort_and_log(HTTPStatus.NOT_FOUND, str(e), include_exc_info=True)
def diffexp_obs_post(request, data_adaptor):
if not data_adaptor.dataset_config.diffexp__enable:
return abort(HTTPStatus.NOT_IMPLEMENTED)
args = request.get_json()
try:
# TODO: implement varfilter mode
mode = DiffExpMode(args["mode"])
if mode == DiffExpMode.VAR_FILTER or "varFilter" in args:
return abort_and_log(HTTPStatus.NOT_IMPLEMENTED, "varFilter not enabled")
set1_filter = args.get("set1", {"filter": {}})["filter"]
set2_filter = args.get("set2", {"filter": {}})["filter"]
count = args.get("count", None)
if set1_filter is None or set2_filter is None or count is None:
return abort_and_log(HTTPStatus.BAD_REQUEST, "missing required parameter")
if Axis.VAR in set1_filter or Axis.VAR in set2_filter:
return abort_and_log(HTTPStatus.BAD_REQUEST, "var axis filter not enabled")
except (KeyError, TypeError) as e:
return abort_and_log(HTTPStatus.BAD_REQUEST, str(e), include_exc_info=True)
try:
diffexp = data_adaptor.diffexp_topN(set1_filter, set2_filter, count)
return make_response(diffexp, HTTPStatus.OK, {"Content-Type": "application/json"})
except (ValueError, DisabledFeatureError, FilterError, ExceedsLimitError) as e:
return abort_and_log(HTTPStatus.BAD_REQUEST, str(e), include_exc_info=True)
except JSONEncodingValueError:
# JSON encoding failure, usually due to bad data. Just let it ripple up
# to default exception handler.
current_app.logger.warning(JSON_NaN_to_num_warning_msg)
raise
def layout_obs_get(request, data_adaptor):
fields = request.args.getlist("layout-name", None)
num_columns_requested = len(data_adaptor.get_embedding_names()) if len(fields) == 0 else len(fields)
if data_adaptor.server_config.exceeds_limit("column_request_max", num_columns_requested):
return abort(HTTPStatus.BAD_REQUEST)
preferred_mimetype = request.accept_mimetypes.best_match(["application/octet-stream"])
if preferred_mimetype != "application/octet-stream":
return abort(HTTPStatus.NOT_ACCEPTABLE)
try:
return make_response(
data_adaptor.layout_to_fbs_matrix(fields), HTTPStatus.OK, {"Content-Type": "application/octet-stream"}
)
except (KeyError, DatasetAccessError) as e:
return abort_and_log(HTTPStatus.BAD_REQUEST, str(e), include_exc_info=True)
except PrepareError:
return abort_and_log(
HTTPStatus.NOT_IMPLEMENTED,
f"No embedding available {request.path}",
loglevel=logging.ERROR,
include_exc_info=True,
)
def layout_obs_put(request, data_adaptor):
if not data_adaptor.dataset_config.embeddings__enable_reembedding:
return abort(HTTPStatus.NOT_IMPLEMENTED)
args = request.get_json()
filter = args["filter"] if args else None
if not filter:
return abort_and_log(HTTPStatus.BAD_REQUEST, "obs filter is required")
method = args["method"] if args else "umap"
try:
schema = data_adaptor.compute_embedding(method, filter)
return make_response(jsonify(schema), HTTPStatus.OK, {"Content-Type": "application/json"})
except NotImplementedError as e:
return abort_and_log(HTTPStatus.NOT_IMPLEMENTED, str(e))
except (ValueError, DisabledFeatureError, FilterError) as e:
return abort_and_log(HTTPStatus.BAD_REQUEST, str(e), include_exc_info=True)
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@@ -1,22 +0,0 @@
class CorporaConstants(object):
REQUIRED_SIMPLE_METADATA_FIELDS = [
"version",
"title",
"layer_descriptions",
"organism",
"organism_ontology_term_id",
]
# The Corpora specification requires some values encoded as JSON due to the inability of AnnData to store complex
# types.
OPTIONAL_JSON_ENCODED_METADATA_FIELD = ["contributors", "project_links"]
OPTIONAL_SIMPLE_METADATA_FIELDS = [
"preprint_doi",
"publication_doi",
"default_embedding",
"default_field",
"tags",
"project_name",
"project_description",
]
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@@ -1,4 +0,0 @@
class CxgConstants(object):
# The CXG container version number. Must be a semver string (major.minor.patch)
# DO NOT UPDATE THIS WITHOUT ALSO UPDATING CXG SPECIFICATION.
CXG_VERSION = "0.2.0"
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@@ -1,178 +0,0 @@
import json
import numpy as np
import tiledb
from server.common.utils.type_conversion_utils import get_dtype_of_array, get_dtype_and_schema_of_array
def convert_dictionary_to_cxg_group(cxg_container, metadata_dict, group_metadata_name="cxg_group_metadata"):
"""
Saves the contents of the dictionary to the CXG output directory specified.
This function is primarily used to save metadata about a dataset to the CXG directory. At some point, tiledb will
have support for metadata on groups at which point the utility of this function should be revisited. Until such
feature exists, this function create an empty array and annotate that array.
For more information, visit https://github.com/TileDB-Inc/TileDB-Py/issues/254.
"""
array_name = f"{cxg_container}/{group_metadata_name}"
# Because TileDB does not allow one to attach metadata directly to a CXG group, we need to have a workaround
# where we create an empty array and attached the metadata onto to this empty array. Below we construct this empty
# array.
tiledb.from_numpy(array_name, np.zeros((1,)))
with tiledb.DenseArray(array_name, mode="w") as metadata_array:
for key, value in metadata_dict.items():
metadata_array.meta[key] = value
def convert_dataframe_to_cxg_array(cxg_container, dataframe_name, dataframe, index_column_name, ctx):
"""
Saves the contents of the dataframe to the CXG output directory specified.
Current access patterns are oriented toward reading very large slices of the dataframe, one attribute at a time.
Attribute data also tends to be (often) repetitive (bools, categories, strings). Given this, we use a large tile
size (1000) and very aggressive compression levels.
"""
def create_dataframe_array(array_name, dataframe):
tiledb_filter = tiledb.FilterList(
[
# Attempt aggressive compression as many of these dataframes are very repetitive strings, bools and
# other non-float data.
tiledb.ZstdFilter(level=22),
]
)
attrs = [
tiledb.Attr(name=column, dtype=get_dtype_of_array(dataframe[column]), filters=tiledb_filter)
for column in dataframe
]
domain = tiledb.Domain(
tiledb.Dim(domain=(0, dataframe.shape[0] - 1), tile=min(dataframe.shape[0], 1000), dtype=np.uint32)
)
schema = tiledb.ArraySchema(
domain=domain, sparse=False, attrs=attrs, cell_order="row-major", tile_order="row-major"
)
tiledb.DenseArray.create(array_name, schema)
array_name = f"{cxg_container}/{dataframe_name}"
create_dataframe_array(array_name, dataframe)
with tiledb.DenseArray(array_name, mode="w", ctx=ctx) as array:
value = {}
schema_hints = {}
for column_name, column_values in dataframe.items():
dtype, hints = get_dtype_and_schema_of_array(column_values)
value[column_name] = column_values.to_numpy(dtype=dtype)
if hints:
schema_hints.update({column_name: hints})
schema_hints.update({"index": index_column_name})
array[:] = value
array.meta["cxg_schema"] = json.dumps(schema_hints)
tiledb.consolidate(array_name, ctx=ctx)
def convert_ndarray_to_cxg_dense_array(ndarray_name, ndarray, ctx):
"""
Saves contents of ndarray to the CXG output directory specified.
Generally this function is used to convert dataset embeddings. Because embeddings are typically accessed with
very large slices (or all of the embedding), they do not benefit from overly aggressive compression due to their
format. Given this, we use a large tile size (1000) but only default compression level.
"""
def create_ndarray_array(ndarray_name, ndarray):
filters = tiledb.FilterList([tiledb.ZstdFilter()])
attrs = [tiledb.Attr(dtype=ndarray.dtype, filters=filters)]
dimensions = [
tiledb.Dim(
domain=(0, ndarray.shape[dimension] - 1), tile=min(ndarray.shape[dimension], 1000), dtype=np.uint32
)
for dimension in range(ndarray.ndim)
]
domain = tiledb.Domain(*dimensions)
schema = tiledb.ArraySchema(
domain=domain, sparse=False, attrs=attrs, capacity=1_000_000, cell_order="row-major", tile_order="row-major"
)
tiledb.DenseArray.create(ndarray_name, schema)
create_ndarray_array(ndarray_name, ndarray)
with tiledb.DenseArray(ndarray_name, mode="w", ctx=ctx) as array:
array[:] = ndarray
tiledb.consolidate(ndarray_name, ctx=ctx)
def convert_matrix_to_cxg_array(
matrix_name, matrix, encode_as_sparse_array, ctx, column_shift_for_sparse_encoding=None
):
"""
Converts a numpy array matrix into a TileDB SparseArray of DenseArray based on whether `encode_as_sparse_array`
is true or not. Note that when the matrix is encoded as a SparseArray, it only writes the values that are
nonzero. This means that if you count the number of elements in the SparseArray, it will not equal the total
number of elements in the matrix, only the number of nonzero elements.
Furthermore, if the `column_shift_for_sparse_encoding` matrix is not None, this function will subtract the sparse
encoding from the original given matrix and as previously stated, only write the nonzero values to the TileDB
SparseArray.
"""
def create_matrix_array(matrix_name, number_of_rows, number_of_columns, encode_as_sparse_array):
filters = tiledb.FilterList([tiledb.ZstdFilter()])
attrs = [tiledb.Attr(dtype=np.float32, filters=filters)]
if encode_as_sparse_array:
domain = tiledb.Domain(
tiledb.Dim(name="obs", domain=(0, number_of_rows - 1), tile=min(number_of_rows, 512), dtype=np.uint32),
tiledb.Dim(
name="var", domain=(0, number_of_columns - 1), tile=min(number_of_columns, 2048), dtype=np.uint32
),
)
else:
domain = tiledb.Domain(
tiledb.Dim(name="obs", domain=(0, number_of_rows - 1), tile=min(number_of_rows, 50), dtype=np.uint32),
tiledb.Dim(
name="var", domain=(0, number_of_columns - 1), tile=min(number_of_columns, 100), dtype=np.uint32
),
)
schema = tiledb.ArraySchema(
domain=domain, sparse=encode_as_sparse_array, attrs=attrs, cell_order="row-major", tile_order="col-major"
)
if encode_as_sparse_array:
tiledb.SparseArray.create(matrix_name, schema)
else:
tiledb.DenseArray.create(matrix_name, schema)
number_of_rows = matrix.shape[0]
number_of_columns = matrix.shape[1]
stride = min(int(np.power(10, np.around(np.log10(1e9 / number_of_columns)))), 10_000)
create_matrix_array(matrix_name, number_of_rows, number_of_columns, encode_as_sparse_array)
if encode_as_sparse_array:
with tiledb.SparseArray(matrix_name, mode="w", ctx=ctx) as array:
for start_row_index in range(0, number_of_rows, stride):
end_row_index = min(start_row_index + stride, number_of_rows)
matrix_subset = matrix[start_row_index:end_row_index, :]
if not isinstance(matrix_subset, np.ndarray):
matrix_subset = matrix_subset.toarray()
if column_shift_for_sparse_encoding is not None:
matrix_subset = matrix_subset - column_shift_for_sparse_encoding
indices = np.nonzero(matrix_subset)
trow = indices[0] + start_row_index
array[trow, indices[1]] = matrix_subset[indices[0], indices[1]]
else:
with tiledb.DenseArray(matrix_name, mode="w", ctx=ctx) as array:
for start_row_index in range(0, number_of_rows, stride):
end_row_index = min(start_row_index + stride, number_of_rows)
matrix_subset = matrix[start_row_index:end_row_index, :]
if not isinstance(matrix_subset, np.ndarray):
matrix_subset = matrix_subset.toarray()
array[start_row_index:end_row_index, :] = matrix_subset
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@@ -1,115 +0,0 @@
import logging
import numpy as np
from scipy.stats import mode
def is_matrix_sparse(matrix: np.ndarray, sparse_threshold):
"""
Returns whether `matrix` is sparse or not (i.e. dense). This is determined by figuring out whether the matrix has
a sparsity percentage below the sparse_threshold, returning the number of non-zeros encountered and number of
elements evaluated. This function may return before evaluating the whole matrix if it can be determined that matrix
is not sparse enough.
"""
if sparse_threshold == 100.0:
return True
if sparse_threshold == 0.0:
return False
total_number_of_rows = matrix.shape[0]
total_number_of_columns = matrix.shape[1]
total_number_of_matrix_elements = total_number_of_rows * total_number_of_columns
# For efficiency, we count the number of non-zero elements in chunks of the matrix at a time until we hit the
# maximum number of non zero values allowed before the matrix is deemed "dense." This allows the function the
# quit early for large dense matrices.
row_stride = min(int(np.power(10, np.around(np.log10(1e9 / total_number_of_columns)))), 10_000)
maximum_number_of_non_zero_elements_in_matrix = int(
total_number_of_rows * total_number_of_columns * sparse_threshold / 100
)
number_of_non_zero_elements = 0
for start_row_index in range(0, total_number_of_rows, row_stride):
end_row_index = min(start_row_index + row_stride, total_number_of_rows)
matrix_subset = matrix[start_row_index:end_row_index, :]
if not isinstance(matrix_subset, np.ndarray):
matrix_subset = matrix_subset.toarray()
number_of_non_zero_elements += np.count_nonzero(matrix_subset)
if number_of_non_zero_elements > maximum_number_of_non_zero_elements_in_matrix:
if end_row_index != total_number_of_rows:
percentage_of_non_zero_elements = (
100 * number_of_non_zero_elements / (end_row_index * total_number_of_columns)
)
logging.info(
f"Matrix is not sparse. Percentage of non-zero elements (estimate): "
f"{percentage_of_non_zero_elements:6.2f}"
)
else:
percentage_of_non_zero_elements = 100 * number_of_non_zero_elements / total_number_of_matrix_elements
logging.info(
f"Matrix is not sparse. Percentage of non-zero elements (exact): "
f"{percentage_of_non_zero_elements:6.2f}"
)
return False
is_sparse = (100.0 * number_of_non_zero_elements / total_number_of_matrix_elements) < sparse_threshold
return is_sparse
def get_column_shift_encode_for_matrix(matrix, sparse_threshold):
"""
Returns a column shift if there is a column shift that allows the given matrix to be considered as sparse. Column
shift encoding works by taking the most common value in each column, then subtracting that value from each element
of the column. If each column mostly contains its most common value, then the resulting matrix can be very sparse.
This function determines if column shift encoding can be used to transform the matrix into a sparse matrix with a
sparsity below the sparse_threshold. If so, returns the array that stores this encoding. This function also returns
the number of non-zeros encountered and number of elements evaluated. This function may return before evaluating
the whole matrix if it can be determined that the matrix cannot benefit from column shift encoding.
"""
total_number_of_rows = matrix.shape[0]
total_number_of_columns = matrix.shape[1]
total_number_of_matrix_elements = total_number_of_rows * total_number_of_columns
stride = max(1, 128_000_000 // total_number_of_rows)
column_shift = np.zeros(total_number_of_columns)
maximum_number_of_non_zero_elements_in_matrix = int(
total_number_of_rows * total_number_of_columns * sparse_threshold / 100
)
number_of_non_zero_elements = 0
for start_column_index in range(0, total_number_of_columns, stride):
end_column_index = min(start_column_index + stride, total_number_of_columns)
matrix_subset = matrix[:, start_column_index:end_column_index]
if not isinstance(matrix_subset, np.ndarray):
matrix_subset = matrix_subset.toarray()
matrix_subset_mode = mode(matrix_subset)
column_shift[start_column_index:end_column_index] = matrix_subset_mode.mode
number_of_non_zero_elements += total_number_of_rows * (end_column_index - start_column_index) - np.sum(
matrix_subset_mode.count
)
if number_of_non_zero_elements > maximum_number_of_non_zero_elements_in_matrix:
if end_column_index != total_number_of_columns:
logging.info(
"Matrix is not sparse even with column shift. Percentage of non-zero elements (estimate): %6.2f"
% (100 * number_of_non_zero_elements / end_column_index * total_number_of_rows)
)
else:
logging.info(
"Matrix is not sparse even with column shift. Percentage of non-zero elements (exact): %6.2f"
% (100 * number_of_non_zero_elements / total_number_of_matrix_elements)
)
return None
is_sparse = (100.0 * number_of_non_zero_elements / total_number_of_matrix_elements) < sparse_threshold
return column_shift if is_sparse else None
-40
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@@ -1,40 +0,0 @@
import re
def sanitize_values_in_list(list_of_keys: list):
"""
Returns a dictionary mapping of the old keys in the list of `list_of_keys` to its new, clean name that is both
safe and unique.
"""
if not all([isinstance(key, str) for key in list_of_keys]):
raise Exception("List of keys to sanitize must contain all strings.")
# Mask out [~/.] and anything outside the ASCII range.
mask = re.compile(r"[^ -\-0-\[\]-\}]")
clean_keys_list = [mask.sub("_", key) for key in list_of_keys]
# Dedupe the clean keys list
deduped_clean_keys_list = []
for index, clean_key in enumerate(clean_keys_list):
total_occurrences_of_clean_key = clean_keys_list.count(clean_key)
total_occurrences_up_until_current_index = clean_keys_list[:index].count(clean_key)
deduped_clean_keys_list.append(
clean_key + "_" + str(total_occurrences_up_until_current_index + 1)
if total_occurrences_of_clean_key > 1
else clean_key
)
return dict(zip(list_of_keys, deduped_clean_keys_list))
def sanitize_keys_in_dictionary(dict_to_sanitize: dict):
"""
Clean and dedupe the keys in the given dictionary.
"""
clean_keys = sanitize_values_in_list(dict_to_sanitize.keys())
for original_key, sanitized_key in clean_keys.items():
if original_key != sanitized_key:
dict_to_sanitize[sanitized_key] = dict_to_sanitize[original_key]
del dict_to_sanitize[original_key]
@@ -1,158 +0,0 @@
import logging
import numpy as np
import pandas as pd
def get_dtypes_and_schemas_of_dataframe(dataframe: pd.DataFrame):
dtypes_by_column_name = {}
schema_type_hints_by_column_name = {}
for column_name, column_values in dataframe.items():
(
dtypes_by_column_name[column_name],
schema_type_hints_by_column_name[column_name],
) = get_dtype_and_schema_of_array(column_values)
return dtypes_by_column_name, schema_type_hints_by_column_name
def get_dtype_of_array(array: pd.Series):
return get_dtype_and_schema_of_array(array)[0]
def get_schema_type_hint_of_array(array: pd.Series):
return get_dtype_and_schema_of_array(array)[1]
def get_dtype_and_schema_of_array(array: pd.Series):
return (
get_dtype_from_dtype(array.dtype, array_values=array),
get_schema_type_hint_from_dtype(array.dtype, array_values=array),
)
def get_dtype_from_dtype(dtype, array_values=None):
"""
Given a data type, finds the equivalent data type that the array should be encoded as. Notably, this is relevant
for 64 bit values which will get downcast to 32 bit.
"""
dtype_name = dtype.name
dtype_kind = dtype.kind
if dtype_name == "bool":
return np.uint8
if dtype_name == "object" and dtype_kind == "O":
return str
if dtype_name == "category":
return get_dtype_from_dtype(dtype.categories.dtype, array_values)
if can_cast_to_int32(dtype, array_values):
return np.int32
if can_cast_to_float32(dtype, array_values):
return np.float32
if not can_cast_to_float32(dtype, array_values):
return np.float64
raise TypeError(f"Annotations of type {dtype} are unsupported.")
def get_schema_type_hint_from_dtype(dtype, array_values=None):
"""
Returns a dictionary that contains type hints about the data type given, especially if the data type is 64 bit
and will be downcast to 32 bit.
"""
dtype_name = dtype.name
dtype_kind = dtype.kind
if dtype == np.float32 or dtype == np.int32:
return {"type": dtype_name}
if dtype_name == "bool":
return {"type": "boolean"}
if dtype_name == "object" and dtype_kind == "O":
return {"type": "string"}
if dtype_name == "category":
return {"type": "categorical", "categories": dtype.categories.tolist()}
if can_cast_to_int32(dtype, array_values):
return {"type": "int32"}
if can_cast_to_float32(dtype, array_values):
return {"type": "float32"}
if dtype_kind == "f" and not can_cast_to_float32(dtype, array_values):
return {"type": "float64"}
raise TypeError(f"Annotations of type {dtype} are unsupported.")
def can_cast_to_float32(dtype, array_values):
"""
Optimistically returns True signifying that a type downcast to float32 is possible whenever the incoming type is
a float.
We also handle a special case here where the array is a Series object with integer categorical values AND NaNs.
Since NaNs are floating points in numpy, we upcast the integer array to float32 and return True.
"""
if dtype.kind == "f":
if not np.can_cast(dtype, np.float32):
logging.warning(f"Type {dtype.name} will be converted to 32 bit float and may lose precision.")
return True
if dtype.kind == "O" and array_values.hasnans:
return True
return False
def can_cast_to_int32(dtype, array_values=None):
"""
A type can be cast to 32 bit, overriding the numpy `cast_cast` function if the values in the array that are of
the higher precision type has values that are entirely within the range of the downcast type.
"""
# Since a NaN is technically a float, any array that contains NaNs cannot be cast to an integer so immediately
# return False.
if array_values.hasnans:
return False
# If the array is categorical, then we need to order the array values so that functions min and max that occur
# later, can function. They do not function on unordered categories.
ordered_array_values = array_values
if array_values.dtype.name == "category" and not array_values.cat.ordered:
ordered_array_values = array_values.cat.as_ordered()
if dtype.kind in ["i", "u"]:
if np.can_cast(dtype, np.int32):
return True
ii32 = np.iinfo(np.int32)
if (
not ordered_array_values.empty
and (ordered_array_values.min() >= ii32.min and ordered_array_values.max() <= ii32.max)
or ordered_array_values.empty
):
return True
return False
def convert_pandas_series_to_numpy(series_to_convert: pd.Series, dtype):
if series_to_convert.hasnans and dtype == np.int32:
logging.error("Cannot convert a pandas Series object to an integer dtype if it contains NaNs.")
return series_to_convert.to_numpy(dtype)
def convert_string_to_value(value: str):
"""convert a string to value with the most appropriate type"""
if value.lower() == "true":
return True
if value.lower() == "false":
return False
if value == "null":
return None
try:
return eval(value)
except: # noqa E722
return value
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@@ -1,118 +0,0 @@
import contextlib
import errno
import importlib.util
import logging
import os
import pkgutil
import socket
from urllib.parse import urlsplit, urljoin
import numpy as np
from flask import json
from server.common.errors import ConfigurationError
def find_available_port(host, port=5005):
"""
Helper method to find open port on host. Tries 5000 ports incremented from the specified port
"""
# Takes approx 2 seconds to do a scan of 5000 ports on my laptop
num_ports_to_try = 5000
for port_to_try in range(port, port + num_ports_to_try):
if is_port_available(host, port_to_try):
return port_to_try
raise socket.error(errno.EADDRINUSE, f"No port in range {port} - {port + num_ports_to_try - 1} available.")
def is_port_available(host, port):
is_available = False
with contextlib.closing(socket.socket(socket.AF_INET, socket.SOCK_STREAM)) as s:
try:
s.bind((host, port))
is_available = True
except socket.error:
pass
return is_available
def sort_options(command):
"""
Helper for the click options - will sort options in a command, and can
be used as a decorator.
"""
command.params.sort(key=lambda p: p.name)
return command
def path_join(base, *urls):
"""
this is like urllib.parse.urljoin, except it works around the scheme-specific
cleverness in the aforementioned code, ignores anything in the url except the path,
and accepts more than one url.
"""
if not base.endswith("/"):
base += "/"
btpl = urlsplit(base)
path = btpl.path
for url in urls:
utpl = urlsplit(url)
if btpl.scheme == "":
path = os.path.join(path, utpl.path)
path = os.path.normpath(path)
else:
path = urljoin(path, utpl.path)
return btpl._replace(path=path).geturl()
class Float32JSONEncoder(json.JSONEncoder):
def __init__(self, *args, **kwargs):
"""
NaN/Infinities are illegal in standard JSON. Python extends JSON with
non-standard symbols that most JavaScript JSON parsers do not understand.
The `allow_nan` parameter will force Python simplejson to throw an ValueError
if it runs into non-finite floating point values which are unsupported by
standard JSON.
"""
kwargs["allow_nan"] = False
super().__init__(*args, **kwargs)
def default(self, obj):
if isinstance(obj, np.float32):
return float(obj)
elif isinstance(obj, np.integer):
return int(obj)
return json.JSONEncoder.default(self, obj)
def custom_format_warning(msg, *args, **kwargs):
return f"[cellxgene] Warning: {msg} \n"
def jsonify_numpy(data):
return json.dumps(data, cls=Float32JSONEncoder, allow_nan=False)
def import_plugins(plugin_module):
"""
Load optional plugin modules from server.common.plugins
If you would like to customize cellxgene, you can add submodules to server.common.plugins before running the app.
This code will import each, loading the code in each. If no plugins are defined, initializing the app continues as
normal.
"""
loaded_modules = []
try:
pkg = importlib.import_module(plugin_module)
for loader, name, is_pkg in pkgutil.walk_packages(pkg.__path__):
full_name = f"{plugin_module}.{name}"
try:
module = importlib.import_module(full_name)
except Exception as e:
raise ConfigurationError(f"Unexpected error while importing plugin: {plugin_module}.{name}: {str(e)}")
loaded_modules.append(module)
except ModuleNotFoundError as e:
# This exception occurs when the plugin_module does not exist (not an error).
logging.debug(f"No plugins found in module: {plugin_module}: {str(e)}")
return loaded_modules
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