diff --git a/local_server/requirements.txt b/local_server/requirements.txt
index f60c5b13..b6e85890 100644
--- a/local_server/requirements.txt
+++ b/local_server/requirements.txt
@@ -13,6 +13,7 @@ flatten-dict>=0.2.0
 fsspec>=0.4.4,<0.8.0
 gunicorn>=20.0.4
 h5py<3.0.0 # h5py>=3.0.0 had a breaking change; there is a fix in anndata>=0.7.5
+numba>=0.49.1,<0.53.0
 numpy>=1.15.0
 packaging>=20.0
 pandas>=1.0,!=1.1  # pandas 1.1 breaks tests, https://github.com/pandas-dev/pandas/issues/35446
diff --git a/server/requirements.txt b/server/requirements.txt
index 1cfdf7d5..4f59451c 100644
--- a/server/requirements.txt
+++ b/server/requirements.txt
@@ -13,7 +13,7 @@ flatten-dict>=0.2.0
 fsspec>=0.4.4,<0.8.0
 gunicorn>=20.0.4
 h5py<3.0.0 # h5py>=3.0.0 had a breaking change; there is a fix in anndata>=0.7.5
-numba>=0.49.1
+numba>=0.49.1,<0.53.0
 numpy>=1.15.0
 packaging>=20.0
 pandas>=1.0,!=1.1  # pandas 1.1 breaks tests, https://github.com/pandas-dev/pandas/issues/35446