diff --git a/server/requirements.txt b/server/requirements.txt
index 6400b1b3..2678a572 100644
--- a/server/requirements.txt
+++ b/server/requirements.txt
@@ -17,5 +17,4 @@ PyYAML>=5.3
 scipy>=1.3.0
 requests>=2.22.0
 tiledb>=0.5.3
-# s3fs, issue 313 breaks cellxgene
-s3fs==0.4.0
+s3fs>=0.4.0,!=0.4.1