Released minimap2-2.3 (r531)

This commit is contained in:
Heng Li
2017-10-22 23:13:35 -04:00
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Release 2.3-r531 (22 October 2017)
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This release come with many improvements and bug fixes:
* The **sr** preset now supports paired-end short-read alignment. Minimap2 is
3-4 times as fast as BWA-MEM, but is slightly less accurate on simulated
reads.
* Meticulous improvements to assembly-to-assembly alignment (special thanks to
Alexey Gurevich from the QUAST team): a) apply a small penalty to matches
between ambiguous bases; b) reduce missing alignments due to spurious
overlaps; c) introduce the short form of the `cs` tag, an improvement to the
SAM MD tag.
* Make sure gaps are always left-aligned.
* Recognize `U` bases from Oxford Nanopore Direct RNA-seq (#33).
* Fixed slightly wrong chaining score. Fixed slightly inaccurate coordinates
for split alignment.
* Fixed multiple reported bugs: 1) wrong reference name for inversion
alignment (#30); 2) redundant SQ lines when multiple query files are
specified (#39); 3) non-functioning option `-K` (#36).
This release has implemented all the major features I planned five months ago,
with the addition of spliced long-read alignment. The next couple of releases
will focus on fine tuning of base algorithms.
(2.3: 22 October 2017, r531)
Release 2.2-r409 (17 September 2017)
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