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Get documentation ready for release
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.TH minimap2 1 "12 July 2017" "minimap2-2.0-r174-pre" "Bioinformatics tools"
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.TH minimap2 1 "18 July 2017" "minimap2-2.0-r180-dirty" "Bioinformatics tools"
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.SH NAME
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.PP
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minimap2 - mapping and alignment between collections of DNA sequences
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@@ -326,14 +326,22 @@ cg Z CIGAR string (only in PAF)
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.TE
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.SH LIMITATIONS
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.PP
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.TP 2
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*
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At the alignment phase, minimap2 performs global alignments between minimizer
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hits. If the positions of these minimizer hits are incorrect, the final alignment
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may be suboptimal or broken due to the Z-drop heuristics. In addition, in the
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event of a long insertion/deletion, minimap2 may split the long event into
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a few smaller events. We will address these issues in future.
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.PP
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hits. If the positions of these minimizer hits are incorrect, the final
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alignment may be suboptimal or unnecessarily fragmented.
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.TP
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*
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Minimap2 may produce poor alignments that may need post-filtering. We are still
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exploring a reliable and consistent way to report good alignments.
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.TP
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*
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Minimap2 does not work well with Illumina short reads as of now.
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.TP
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*
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Minimap2 requires SSE2 instructions to compile. It is possible to add
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non-SSE2 support, but it would minimap2 times slower.
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.SH SEE ALSO
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.PP
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miniasm(1), minimap(1), bwa(1).
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