diff --git a/align.c b/align.c
index 01946e4..374d607 100644
--- a/align.c
+++ b/align.c
@@ -364,7 +364,7 @@ static void mm_align_pair(void *km, const mm_mapopt_t *opt, int qlen, const uint
 	else if (opt->q == opt->q2 && opt->e == opt->e2)
 		ksw_extz2_sse(km, qlen, qseq, tlen, tseq, 5, mat, opt->q, opt->e, w, zdrop, end_bonus, flag, ez);
 	else{
-#ifdef ALIGN_AVX
+#ifdef ALIGN_AVX && (__AVX512BW__ || __AVX2__)
 #ifdef __AVX512BW__
             	ksw_extd2_avx512(km, qlen, qseq, tlen, tseq, 5, mat, opt->q, opt->e, opt->q2, opt->e2, w, zdrop, end_bonus, flag, ez);
 #elif __AVX2__
diff --git a/chain.c b/chain.c
index 94e9be0..ef8509f 100644
--- a/chain.c
+++ b/chain.c
@@ -68,7 +68,7 @@ mm128_t *mm_chain_dp(int max_dist_x, int max_dist_y, int bw, int max_skip, int m
 	t = (int32_t*)kmalloc(km, n * 4);
 	v = (int32_t*)kmalloc(km, n * 4);
 	memset(t, 0, n * 4);
-#if VECTORIZED_CHAINING
+#if VECTORIZED_CHAINING && (__AVX512BW__ || __AVX2__)
 	anchor_t* anchors = (anchor_t*)malloc(n* sizeof(anchor_t));
 	for (i = 0; i < n; ++i) {
 		uint64_t ri = a[i].x;