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r421: removed the MM_F_SPLICE_BOTH mode
In the default splice mode, minimap2 applies two rounds of spliced alignment: first assuming GT-AG to be the splice signal across all splicing sites and then assuming CT-AC to be the signal. This is the idea strategy. In the MM_F_SPLICE_BOTH mode, minimap2 applies one round of spliced alignment, assuming GT-AG and CT-AC to be the splice signals AT THE SAME TIME. This will be faster but less accurate. I don't think anyone would like to run minimap2 in this mode, so I am removing it for clarity.
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@@ -12,10 +12,9 @@
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#define MM_F_NO_QUAL 0x010
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#define MM_F_OUT_CG 0x020
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#define MM_F_OUT_CS 0x040
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#define MM_F_SPLICE 0x080
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#define MM_F_SPLICE_FOR 0x100
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#define MM_F_SPLICE_REV 0x200
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#define MM_F_SPLICE_BOTH 0x400
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#define MM_F_SPLICE 0x080 // splice mode
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#define MM_F_SPLICE_FOR 0x100 // match GT-AG
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#define MM_F_SPLICE_REV 0x200 // match CT-AC, the reverse complement of GT-AG
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#define MM_F_NO_SAM_SQ 0x800
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#define MM_F_APPROX_EXT 0x1000
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