clarify that wrong seeding mainly occurs in LCRs

2026-10-02 17:08:12 +08:00 · 2017-07-28 14:33:15 -04:00
parent ebbe9c1eb8
commit 84922cfe41
2 changed files with 6 additions and 9 deletions
@@ -86,10 +86,8 @@ highlighted in bold.

 ## Limitations

-* At the alignment phase, minimap2 performs global alignments between minimizer
-  hits. If the positions of these minimizer hits are incorrect, the final
-  alignment may be suboptimal or unnecessarily fragmented. This should happen
-  rarely with the latest version.
+* Minimap2 may produce suboptimal alignments through long low-complexity
+  regions where seed positions may be inaccurate.

 * Minimap2 may produce poor alignments that may need post-filtering. We are
  still exploring a reliable and consistent way to report good alignments.