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r524: reverted to bwa-mem end bonus
and reduced the cost of clipping when filtering by identity
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@@ -512,7 +512,11 @@ We evaluated minimap2 along with Bowtie2~\citep{Langmead:2012fk}, BWA-MEM and
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SNAP~\citep{Zaharia:2011aa}. Minimap2 is 3--4 times as fast as Bowtie2 and
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BWA-MEM, but is 1.3 times slower than SNAP. Minimap2 is more accurate on this
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simulated data set than Bowtie2 and SNAP but less accurate than BWA-MEM
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(Fig.~\ref{fig:eval}b).
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(Fig.~\ref{fig:eval}b). Closer investigation reveals that BWA-MEM achieves
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a higher accuracy partly because it tries to locally align a read in a small
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region close to its mate. If we disable this feature, BWA-MEM becomes slightly
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less accurate than minimap2. We might consider to implement a similar heuristic
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in minimap2 in future.
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\section{Conclusion}
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