response to reviewers' comments, round 2

This commit is contained in:
Heng Li
2018-03-15 21:59:57 -04:00
parent 242ff4e91d
commit d135feb1a5
3 changed files with 55 additions and 40 deletions
+21 -12
View File
@@ -1,4 +1,4 @@
.TH minimap2 1 "24 February 2018" "minimap2-2.9 (r720)" "Bioinformatics tools"
.TH minimap2 1 "15 March 2018" "minimap2-2.9-dirty (r746)" "Bioinformatics tools"
.SH NAME
.PP
minimap2 - mapping and alignment between collections of DNA sequences
@@ -123,10 +123,27 @@ provided as the target sequences, options
will be effectively overridden by the options stored in the index file.
.SS Mapping options
.TP 10
.BI -f \ FLOAT
Ignore top
.BI -f \ FLOAT | INT1 [, INT2 ]
If fraction, ignore top
.I FLOAT
fraction of most frequent minimizers [0.0002]
fraction of most frequent minimizers [0.0002]. If integer,
ignore minimizers occuring more than
.I INT1
times.
.I INT2
is only effective in the
.B --sr
or
.B -xsr
mode, which sets the threshold for a second round of seeding.
.TP
.BI --min-occ-floor \ INT
Force minimap2 to always use k-mers occurring
.I INT
times or less [0]. In effect, the max occurrence threshold is set to
the
.RI max{ INT ,
.BR -f }.
.TP
.BI -g \ INT
Stop chain enlongation if there are no minimizers within
@@ -217,14 +234,6 @@ on chains. Set
.I INT
to a large number to switch off this heurstics.
.TP
.BI --min-occ-floor \ INT
Force minimap2 to always use k-mers occurring
.I INT
times or less [0]. In effect, the max occurrence threshold is set to
the
.RI max{ INT ,
.BR -f }.
.TP
.B --no-long-join
Disable the long gap patching heuristic. When this option is applied, the
maximum alignment gap is mostly controlled by