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update readme and help information
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@@ -33,9 +33,7 @@ outputs consist of:
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So far hifiasm is still in early development stage, it will output phased
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chromosome-level high-quality assembly in the near future. In addition, hifiasm
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also outputs three binary files that save all overlap inforamtion
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(hifiasm.asm.gfa.aux.bin, hifiasm.asm.gfa.aux.reverse.bin,
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hifiasm.asm.gfa.aux.source.bin in default). With these files, hifiasm can avoid
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the time-consuming all-to-all overlap calculation step, and do the assembly
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(hifiasm.asm.ovlp, hifiasm.asm.ovlp.source, hifiasm.asm.ovlp.reverse in default). With these files, hifiasm can avoid the time-consuming all-to-all overlap calculation step, and do the assembly
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directly and quickly. This might be helpful when you want to get an optimized
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assembly by multiple round of experiments with different parameters.
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@@ -70,8 +68,7 @@ all overlaps to disk, which can avoid the time-consuming all-to-all overlap
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calculation next time. For hifiasm, once the overlap information has been
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obtained during the previous run in advance, it is able to load all overlaps
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from disk and then directly do assembly. If you want to ignore the pre-computed
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overlap information, please specify `-i` or simply delete `*gfa.aux.bin`,
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`*gfa.aux.reverse.bin` and `*gfa.aux.source.bin`.
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overlap information, please specify `-i` or simply delete `*.ovlp`, `*.ovlp.source` and `*.ovlp.reverse`.
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Please note that some old Hifi reads may consist of short adapters. To improve
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the assembly quality, adapters should be removed by `-z` as follow:
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