diff --git a/README.md b/README.md index 0dbed96..ba52a5b 100644 --- a/README.md +++ b/README.md @@ -73,7 +73,7 @@ all overlaps to disk, which can avoid the time-consuming all-to-all overlap calculation next time. For hifiasm, once the overlap information has been obtained during the previous run in advance, it is able to load all overlaps from disk and then directly do assembly. If you want to ignore the pre-computed -overlap information, please specify `-i` or simply delete `*.ovlp`, `*.ovlp.source` and `*.ovlp.reverse`. +overlap information, please specify `-i`. Please note that some old Hifi reads may consist of short adapters. To improve the assembly quality, adapters should be removed by `-z` as follow: