Commit Graph

97 Commits

Author SHA1 Message Date
Bruce Martin
f2fbeff511 add support for corpora default_embedding field (#1696)
* fix mispelling

* re-implement re-embedding

* always load base embedding to fetch counts

* format

* lint

* fix tests

* lint

* fix accept handling

* test log

* more debug

* more

* more

* more

* more

* remove logging

* logging

* jsonify

* remove debugging logs

* lint

* clean up errors a bit

* fix issue found in PR review

* add support for corpora default_embedding

* fix botched merge

* PR review

* PR review
2020-07-31 07:36:48 -07:00
Bruce Martin
75cb513dd9 re-implement re-embeddings (#1679)
* fix mispelling

* re-implement re-embedding

* always load base embedding to fetch counts

* format

* lint

* fix tests

* lint

* fix accept handling

* test log

* more debug

* more

* more

* more

* more

* remove logging

* logging

* jsonify

* remove debugging logs

* lint

* clean up errors a bit

* fix issue found in PR review

* PR review changes
2020-07-30 12:31:36 -07:00
Bruce Martin
59f989d26f initial support for corpora schema conventions (#1676)
* initial support for corpora schema conventions

* remove debugging print

* add corpora util module

* tests

* lint

* PR review edits

* PR changes

* more PR changes

* more PR chnages

* PR fixes

* formatting

* PR updates

* lint

* PR review
2020-07-28 17:32:27 -07:00
bmccandless
5285556415 Add basic authentication in the server (#1670)
* Add basic authentication in the server

A pattern for creating authentication methods is introduced, with three
authentication types defined:
  none - no authentication
  session - like the current session based auth used for user annotations
  test - used to test the login/logout process end to end

The config endpoint now returns informations about the authentication, like if
the user is authenticated and their username.  The redirect uri's for login and
logout are also returned if the authentication type requires login

This is the first a several PRs for authentication.

*. Update server tests to avoid hardcoded ports

test_api and test_nan_rest now use a common function for starting a test server,
than will initially choose a random port.
2020-07-28 13:28:30 -07:00
bmccandless
0344cfacce Fix the app config for reembedding and add a test (#1664)
* Fix the app config for reembedding and add a test

* Add scanpy to requirements-dev
2020-07-23 12:27:53 -07:00
bmccandless
3c6d90a4db Better error checking on bad params (#1626) 2020-07-16 11:08:27 -07:00
bmccandless
f69d141336 refactor config to support different config options for datasets in different dataroots. (#1596)
This will give us the ability to specify different config options for
different dataroots.

the key of the dataroot dictionary is no longer the same as the dataroot_url.
Previously key==dataroot_url, and now those are separated.

Added an "is_multi_dataset" function to simplify logic where it branched on single vs multi.

Simplified the rest.py interface by no longer passing in the user annotations object, since
that can be retrieved from the dataset.
2020-07-10 16:21:40 -07:00
Matt Weiden
e5670d1732 Do not cache index.html (#1603)
* Fix typo

* Run black for code formatting

* Do not cache index.html
2020-07-01 14:35:44 -07:00
Matt Weiden
152c07a28e Change default branch from 'master' to 'main' (#1589)
The default branch has been changed. This PR cleans up references to
`master` and fixes links that would otherwise be broken.

For more background see the following references:
* https://www.independent.co.uk/life-style/gadgets-and-tech/news/github-master-slave-slavery-whitelist-language-inclusive-a9568576.html
* https://tools.ietf.org/id/draft-knodel-terminology-00.html
2020-06-25 14:04:30 -07:00
bmccandless
99d004d1f0 add config option to handle multiple dataroots (#1531)
#1513
2020-06-04 19:29:37 -07:00
bmccandless
76523d4f32 sparse column shift encoding. (#1502)
Many of our matrices are log normalized, which tends to eliminate
the number of non zero values (if there were any).  This prevents
the matrix from being stored as a sparse matrix.  The solution here
is to use a simple transformation to make it sparse again.  The most
common value from each column is subtracted from that column.  These
values that were subtracted are saved in an array called X_col_shift.

The cellxgene code needs to understand how to undo the transformation when
operating over the X matrix.

- added script to create a synthetic dataset for testing
- added a script to convert an existing CXG dataset to a sparse CXG dataset
2020-06-02 08:23:52 -07:00
bmccandless
d0577b94af Return an empty matrix if no rows or columns are selected (#1501)
Return an empty matrix if no rows or columns are selected

Fixes #1499
2020-05-29 14:47:46 -07:00
bmccandless
f7585eef1e Support for sparse tiledb arrays for the X matrix (#1496)
Support for sparse tiledb arrays for the X matrix

1. cxgtool can now output sparse matrices
2. cxg_adaptor and diffexp_cxg updated to handle sparse matrices
3. added a test in test_diffexp to test sparse diffexp and get_X_array
2020-05-28 18:36:02 -07:00
bmccandless
030eea1898 Update run_diffexp.py (#1494)
You can now select labels within groups instead of random rows.
2020-05-26 16:06:33 -07:00
Matt Weiden
730410c5e1 Autoformat python to fix lint errors (#1470)
* Autoformat python to fix lint errors

* Fix lint errors not caught by black
2020-05-12 13:19:38 -07:00
bmccandless
f49507f18a app_config, fix bug with list/tuple command line arguments. (#1464)
* app_config, fix bug with list/tuple command line arguments.

There was a error caused by pyyaml using lists, and click using tuples.
Now tuples are automatically converted to lists when the config is
updated.
2020-05-06 12:00:02 -07:00
Matt Weiden
5947306ca0 Add server plugin system (#1447)
* Add server plugin system

Plugins are optional modules loaded at runtime. Specification:
* Plugins are loaded from the server.plugins module (directory
  server/plugins)
* The import_plugins method is run as part of the initialization of the
  server module in __init__.py

* Add plugins to the EB build process

* Remove bit of dead code

* Respond to feedback from @bmccandless
2020-05-05 17:05:42 -07:00
Matt Weiden
a17fff83cf Return empty colors for .cxg v0.0 files (#1441)
* Return empty colors for .cxg v0.0 files

Fixes https://github.com/chanzuckerberg/cellxgene/issues/1440

The CxgAdaptor.get_colors method currently assumes that the .cxg file has
cxg_group_metadata. As a result, the /api/v0.2/colors endpoint always fails for
.cxg v0.0 files.

* Add test fixture
2020-04-30 17:21:20 -07:00
Matt Weiden
546e272a60 Add user-defined category-label colors (#1402)
* Add user-defined category-label colors

Fixes https://github.com/chanzuckerberg/cellxgene/issues/1152

As described in https://github.com/chanzuckerberg/cellxgene/issues/1307

* Respond to feedback from @bkmartinjr in nodejs

* Respond to feedback from @bkmartinjr in python

* Add tests to the server module

* Autoformat python, run linter

* Make colors_get error handling specific

* Respond to feedback from @bkmartinjr

* Respond to feedback from @bkmartinjr

* Fix whitespace

* Fix python lint errrors

* Update documentation

* Add --disable-user-colors option to launch and cxgtool.py

* Fix python formatting

* Rename '--disable-user-colors' to '--disable-custom-colors'
2020-04-26 22:52:57 -07:00
Matt Weiden
58e4c2489b Auto format python, make sure it passes lint checks (#1401) 2020-04-16 08:07:10 -07:00
bmccandless
5c0b8c6296 Improve diffexp for tiledb (#1388)
* Improve diffexp for tiledb

- The rows from the A and B sets are gathered and processed at the same time.  In this
  way the matrix is only accessed once instead of twice for each tile.
- There is now a single thread queue that gets shared between all callers of the diffexp.
  This will slow down work if diffexp gets too busy.
- There is a target_workunit amount of work given to each thread.  Previously the
  workunit was (rows selected * width of tile), which could be small.  Now multiple
  column tiles can be combined into one workunit.  If the target is too small then
  thread and other overheads may reduce performance.  If target_workunit is too large
  then the size of the gathered sub matrix may take up too much memory.
- add configuration parameters (max_workers, cpu_multiplier, and  target_workunit)
2020-04-13 18:53:13 -07:00
Bruce Martin
136093d583 add GET routes for expression data (#1387)
* add GET routes for expression data

* fix comment typo
2020-04-13 11:28:35 -07:00
bmccandless
98c2a1359b Specialize diffexp for tiledb (#1384)
* Specialize diffexp for tiledb

This patch adds a new diffexp algorithm which is tuned for tiledb.
This algorithm was written by Bruce and is adapted here to plug into the
current framework.  The anndata_adaptor still calls the original
algotithm (which was move from diffexp.py to diffexp_generic.py).
The cxg_adaptor now calls the new diffexp_tiledb version.  Some
code is shared between the two.

This is part 1 of the diffexp for tiledb.  Further tuning and
global throttles are still needed.

A script to run and time diffexp with various options is also
added: test/run_diffexp.py.
2020-04-12 09:56:55 -07:00
Bruce Martin
0398249a20 CXG performance improvements (#1371)
* initial kv cache

* add per-key locks

* comments

* memoize schema

* add missing initialization

* fix sever timing

* fetch only what is requested

* fix tests to not require strict ordering of columns

* clean up annotation request

* remove debugging print
2020-04-09 10:19:26 -07:00
Bruce Martin
e2a12ba9bb diffexp limit UI and configuration (#1336)
* warning on maxCount for diffexp

* cleanup logging

* clarification

* make the limits configurable

* make diff exp limit work

* danger!

* remove debugging code

* fix merge with master

* fix unit tests

Co-authored-by: Colin Megill <colinmegill@gmail.com>
2020-04-09 07:13:41 -07:00
bmccandless
d457988810 Update for app config (#1369)
fixes an issue with "cellxgene launch" which had a bad interaction between
command line parameters and config file parameters.
Now, the config files are applied first, followed by the parameters that
were provided in the command line.

There is also now a check that each of the config attributes is type checked.
2020-04-08 15:44:56 -07:00
Bruce Martin
bcacb75296 load embeddings in parallel (#1352)
* load embeddings in parallel

* correctly capture unclipped

* test

* another test

* add convenient copy assets target

* cleanup
2020-04-07 09:48:07 -07:00
Bruce Martin
6193ae4997 Cleanup front-end build and python module contents (#1350)
* cleanup build and module contents

* lint

* update chalk

* more cleanup

* fix unit test
2020-04-06 19:04:06 -07:00
bmccandless
308ee64f30 Improvements to the matrix cache (#1340)
* Improvements to the matrix cache

- Add a timelimit for the matrix in the cache.
Once the timelimit is reached, the matrix can be removed.

- If a DatasetAccessError occurs, then remove the dataset
from the matrix cache.

Fixes #1322
2020-04-02 13:44:11 -07:00
Bruce Martin
26605049a4 Various hardening to REST routes (#1293)
* URL reweriting for static

* request size limits

* improve quotas, make tests work

* remove debugging code

* pass limits to front-end

* fix renaming boggle
2020-03-25 16:14:52 -07:00
Bruce Martin
d99b84ba09 prepare - work around anndata bug (#1260)
* work around anndata bug 344

* fix accidental cut and paste error

* Use modified make_index_unique function

Temporarily copy code from https://github.com/theislab/anndata/pull/345
until the issue is resolved and released.

* Add notes and test for make_index_unique

* Lint fix

* Format python

Co-authored-by: Matt Weiden <538456+mweiden@users.noreply.github.com>
2020-03-22 12:27:59 -07:00
bmccandless
8180be83b8 Introduce a config file to cellxgene (#1264)
* Introduce a config file to cellxgene

The config file format is in yaml.  The default config is located
in server/common/default_config.py.  A user may create a yaml file
that contains a subset of these fields.  It can be used during cellxgene
launch, or for hosted cellxgene.

The code has also been refactored.  Much of the logic to check arguments
has moved from launch to app config.

It is now possible to set the tiledb context parameters using the config
file.  Other feature will soon be handled in a similar way.
2020-03-22 09:34:11 -07:00
Sidney Bell
9089fc98f2 annotations cli updates (#1190)
* Switch logic from `--annotations` to `--disable-annotations

* Rename `--annotations-file` --> `--annotations-input-file` and remove `experimental`

* update docs

* update makefile

* update tests

* Disable annotations on standard client smoke test

* Update docs/posts/annotations.md

Co-Authored-By: Matt Weiden <538456+mweiden@users.noreply.github.com>

* Update docs/posts/annotations.md

* Renaming

* Docs

* Update tests

* Pesky typo -_-

Co-authored-by: Matt Weiden <538456+mweiden@users.noreply.github.com>
2020-03-11 11:57:52 -07:00
Bruce Martin
144b19c449 experimental re-embedding (#1186)
* first cut at re-embedding route and back-end support

* update and expand config route tests

* add scanpy_umap

* add reembedding to config route parameters

* front-end support for reembedding fetch and UI

* remove unused imports

* add loading state

* save reembedding in reducer state

* improve withColsFrom

* transmit reembed schema to client; pick unique embedding names

* display embeddings

* format

* lint

* spaces, tab size 2

* lint

* test hack for smoke-test race

* back out hack sleep

* add check for backed mode

* add unit test for reembedding

* lint

* hide re-embedding CLI param from help
2020-03-09 16:53:30 -07:00
Matt Weiden
8a62c9f027 Add undo/redo smoke tests for annotations (#1175)
* Add undo/redo tests for annotations

Fixes https://github.com/chanzuckerberg/cellxgene/issues/969

... also refactor the tests for DRY.

* Add done()

* Make e2e annotations tests safer to concurrency

* Add data-testclass for save state.

* Simplify tests and make them dependent on save state
2020-02-26 12:10:03 -08:00
bmccandless
46876e2fb1 Fix various bugs with CXG format at annotations (#1173)
- Enable testing for this path

 - Fixes #1166
 - Fixes #1167
 - Fixes #1168
2020-02-24 18:19:39 -08:00
Matt Weiden
c7f2032dd7 Add user-generated annotations tests to the server (#1164)
* Add user-generated annotations tests to the server

Partially completes https://github.com/chanzuckerberg/cellxgene/issues/969

* Auto-format python code

* @skip_if: passing lambdas > than property strings

* Respond to feedback from @bkmartinjr
2020-02-23 15:32:13 -08:00
bmccandless
907cc634f5 server refactor (#1140)
This PR contains a refactoring to make adding new features easier.

The new features include supporting the tiledb format, and the multi dataset application.

The refactoring includes

Simplifying the directory structure and files.
a class structure to handle annotations (currently one type: AnnotationsLocalFile).
a class to handle application configuration
a class structure to handle matrix data (currently AnndataAdaptor and CxgAdaptor). CxgAdaptor uses tiledb.
Algorithms that were previously dependent on the scanpy anndata object are now generalized to work with an abstract interface.
The multi dataset option is not fully supported yet, and so the option to use it is hidden.
Use "cli launch --dataroot ..."
To access this feature.

All combinations of app single dataset/ app multi dataset and AnndataAdaptor/CxgAdaptor work with all the features, such as annotations, ontologies, diffexp.
2020-02-19 10:22:35 -08:00
Bruce Martin
349c413d8b anndata X indexing & version compatibility improvements (#1157)
* revert MatrixProxy; replace with correct use of adata slicing

* work around 0.6 adata slicing bug

* fix incorrect var slice

* simplify slicing of X

* add warning about performance impact of anndata<=0.7

* lint and remove unused code

* improve comment

* lint

* correctly parse versions

* temp files should preserve file suffix if possible - anndata 0.7 compat

* update anndata dependency to 0.6.20

* resolve PR review comments
2020-02-19 09:57:51 -07:00
Matt Weiden
d30087ca63 Add frontend smoke tests for annotations (#1154)
* Add smoke test for annotations features

* Do not save during annotations tests

* Fix botched rebase in dev guidelines

* Revert "Do not save during annotations tests"

This reverts commit f0bd970bb2.

* Respond to feedback from @bkmartinjr
2020-02-14 17:23:45 -08:00
Colin Megill
d48647a655 Ontologies (#1110)
* add sample ontologies file

* add ontologies reducer

* Move select category to own component

* Dialog and Input factored out

* refactoring categorical, partway

* validationn

* anno

* suggest  populates input

* frontend for ontology working

* initial implementation of back-end support for ontologies

* edit is now dialog again

* autosuggest working on edit

* part way through create arbitrary label

* handle choice in function

* pass duplicate cat  prop

* editing works

* update test to match new CLI params

* fix occupancy alignment

* edit category as dialogue

* secondary button

* remove stubbed out ontologies

* add label setting upon new label creation

* Update legal characters for labels (#1119)

* Allow any term in the ontology (bypass legal name check)

* Add hyphens and parens to legal characters in names

* improve performance for large ontologies

* correctly handle case where ontologies are disabled

* fix logic error in CLI

Co-authored-by: Bruce Martin <bruce@chanzuckerberg.com>

* PR cleanup 1

* lint

* validate user generated labels

* finish hooking up connected suggest component

* protect against undefined callbacks

* Fix illegal characters error message

* break out npm run commands

* fix error detection on label edit

Co-authored-by: Bruce Martin <bruce@chanzuckerberg.com>
Co-authored-by: Sidney Bell <sidneymbell@users.noreply.github.com>
2020-01-23 17:04:17 -05:00
Matt Weiden
53a6d01fa3 Notify users of new versions of cellxgene (#1078)
* Notify users of new versions of cellxgene

Fixes https://github.com/chanzuckerberg/cellxgene/issues/683

* Do not use PyGithub client

* Protect against AttributeError

* Document that all version tags must follow SemVer

* Release tags `should -> MUST` follow semantic versioning
2019-12-31 17:43:11 -08:00
Matt Weiden
f3015cb9df Makefile modularity, test targets, and auto-formatting (#1070)
* Fix Makefile whitespace and .PHONY use

* Fix Makefile filename

* Modularize Makefile into client and server Makefiles

Part of the reason that the Makefile in the root directory is a bit
complicated is that it tries to handle tasks that can be handled
separately in the client and server modules.

This commit pushes some of the make logic specific to each module into
their own makefiles and calls out to those makefiles from that in the
project root.

* Add auto-formatting to client and server modules

One thing that can make linting faster is auto-formatting. This commit
adds the yapf auto-formatting tool to the server module and uses
eslint's "fix" functionality to speed up the linting/formatting process.

* Add yapf for automatic code formatting

* Add a root test target that calls sub-tests

* Apply yapf to python files

* Do not duplicate npm commands, simply pass through

* Update documentation

* Do not shadow reserved word len

* Add general test target

* Fix make call in dev-env

* Use black instead of yapf

* Run flake8 from the root directory

* Revert "Apply yapf to python files"

This reverts commit cdca128a01.

* Apply black to python code

* Resolve lint errors resulting from black format

* Add explanation of server unit tests in dev guidelines
2019-12-27 14:43:37 -08:00
Bruce Martin
a593e95ab3 annotations CLI and file UX rework (#1049)
* rename config param label-file

* annotations rework - CLI params, file naming and backups

* lint

* improve cli option error checks

* enable session cookies

* enable session cookies

* add session id

* name annotations file in multi-dataset and multi-user safe manner

* pass data user hash to front-end

* add annotation collection name support to front-end

* add constant for annotation data collection name

* parameterize annotation collection name; make it sticky in the session

* clarify comments

* hard wire a temporary data collection name for testing

* prettier

* test comment

* package command

* set annotations  filename dialog

* name  and hash are visible

* wire up data collection capture
2019-11-25 15:28:28 -08:00
Bruce Martin
5ea9ac8a9e Add provenance header to labels CSV file (#1041)
* add last mod time lookup to data locator

* store data locator in Driver

* save metadata header in labels csv

* lint

* fix tests

* change datetime format to second precision
2019-11-14 12:33:48 -08:00
Bruce Martin
711f3b7048 Add support for anndata backed mode (#943)
* initial cut at backed mode

* make flask multithreading conditional on debug flag

* update X access to support backed mode

* lint

* improve help message for backed mode

* fix tests

* add MatrixProxy to normalize supported matrix types

* add FAQ entry for --backed

* remove use of matrix.T

* clean up

* add ability to disable diffexp from CLI; add hueristic to detect likely slow diffexp calculation, and warn user

* fix tests

* do not print diffexp speed warning if diffexp is disabled

* tweak wording of diffexp speed messages

* add FAQ entry on --disable-diffexp

* revise heuristic for warning about slow diffexp

* use quick tooltip delay on diffexp button
2019-10-08 11:16:07 -07:00
Bruce Martin
3d15db7c5e parameterize pbmc3k scanpy engine test (#939) 2019-09-20 17:41:32 -07:00
Bruce Martin
109c9e70ec Add obs index to label file (#928)
* remove debug logging

* load and save obs/row index in label file

* lint

* update tests
2019-09-19 09:16:01 -07:00
Bruce Martin
3660a6cc27 Experimental - manual annotations (#837)
* icons, partway

* redux for values

* onChange

* cancel

* annotations lifecycle for category names

* copy categorical

* edit category

* add Dataframe.withColsFrom

* render user annotations; default add/delete annotation category

* add label name to actions

* category name edit

* error checking improvements

* change schema field isUserAnnotation to writable

* always have an unassigned label; implement delete label

* implement add new label and edit label name

* label current cell selection

* fix select exact bug in crossfilter

* clean up categorical reducer

* fix tests

* remove debugging printf

* implement subset/reset for user annotations

* undo redo support for user annotations

* remove duplicate button from categories

* add modal

* remove obsolete duplicate annotation reducers

* remove old debugging printf

* connect modal to annotation create and dup

* initial full-stack wiring

* finish up end-to-end wiring

* fix existing unit tests

* fix pytests to match new schema API

* remove debugging printfs

* add label file rotation

* remove obsolete comment

* add fbs encode/decode tests

* add tests for writable annotations

* simplify code

* fix hashing bug with FBS encoding

* lint

* fix smoke tests

* improve error checking in Dataframe.withColsFrom

* add unit test for Dataframe.withColsFrom

* add unit test for Dataframe.columns and Dataframe.renameCol

* fix bug in FBS encode, add better error checks, refactor

* add FBS encode/decode test

* add clarifying comment

* clean up action type names; fix state inconsistency in crossfilter update

* change autosave timer to 2.5sec

* sort categorical metadata render order so it remains consistent

* add temporary autogenerated label for add-new-label operation

* fix hover-over label menu interference with cell highlighting

* remove debugging code

* add missing reducer cases & fix typo

* make dataframe memoize more general purpose

* add dev mode for annos

* fix error on select duplicate

* handle zero occupancy categories

* correctly maintain unclipped AND clipped world

* correctly handle zero length FBS matrix and label files

* ensure all writable categorical schema contains an unassigned category

* handle case where building occupancy stack for category with no members

* dialog for creating label, disable button if duplicate or empty

* visually separate writeable

* edit category

* fix edit category name

* remove debugging code

* fix edit annotation label

* visually define unassigned, change options

* Pull in requirements.txt from `master`

* label currently selected cells

* duplicate label

* lint

* fix pytest merge issues

* rename --label-file to --experimental-label-file

* remove debugging console log

* spelling error fix; fix bug found in PR review.

* lint
2019-09-18 07:33:41 -04:00
Bruce Martin
20317fd08f Add URL data locators to launch sub-command (#920)
* initial commit of URL support for launch

* lint

* modify tests to use new data locator

* add locator unit tests

* fix typo in faq

* more lint

* update faq per PR review
2019-09-15 09:01:53 -07:00