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r903: merged extd2_avx512.c into extd2_sse.c

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This commit is contained in:
Heng Li
2019-01-01 13:46:30 -05:00
parent 0b4be2996e
commit f5e2176bc5
4 changed files with 104 additions and 316 deletions
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2
Makefile
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@@ -72,7 +72,7 @@ ksw2_extz2_sse2.o:ksw2_extz2_sse.c ksw2.h kalloc.h
ksw2_extd2_avx2.o:ksw2_extd2_sse.c ksw2.h kalloc.h
$(CC) -c $(CFLAGS) -mavx2 $(CPPFLAGS) -DKSW_CPU_DISPATCH $(INCLUDES) $< -o $@
ksw2_extd2_avx512.o:ksw2_extd2_avx512.c ksw2.h kalloc.h
ksw2_extd2_avx512.o:ksw2_extd2_sse.c ksw2.h kalloc.h
$(CC) -c $(CFLAGS) -mavx512bw $(CPPFLAGS) -DKSW_CPU_DISPATCH $(INCLUDES) $< -o $@
ksw2_extd2_sse41.o:ksw2_extd2_sse.c ksw2.h kalloc.h

300
ksw2_extd2_avx512.c
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@@ -1,300 +0,0 @@
#include <string.h>
#include <stdio.h>
#include <assert.h>
#include "ksw2.h"
#ifdef __AVX512BW__
#include <immintrin.h>
void ksw_extd2_avx512(void *km, int qlen, const uint8_t *query, int tlen, const uint8_t *target, int8_t m, const int8_t *mat,
int8_t q, int8_t e, int8_t q2, int8_t e2, int w, int zdrop, int end_bonus, int flag, ksw_extz_t *ez)
{
#define __dp_code_block1 \
z = _mm512_load_si512(&s[t]); \
tmp = _mm512_loadu_si512((uint8_t*)&x[t] - 1); \
xt1 = _mm512_mask_blend_epi8(1, tmp, x1_); \
x1_ = _mm512_maskz_set1_epi8(1, *((uint8_t*)&x[t] + 63)); \
tmp = _mm512_loadu_si512((uint8_t*)&v[t] - 1); \
vt1 = _mm512_mask_blend_epi8(1, tmp, v1_); \
v1_ = _mm512_maskz_set1_epi8(1, *((uint8_t*)&v[t] + 63)); \
a = _mm512_add_epi8(xt1, vt1); /* a <- x[r-1][t-1..t+62] + v[r-1][t-1..t+62] */ \
ut = _mm512_load_si512(&u[t]); /* ut <- u[t..t+63] */ \
b = _mm512_add_epi8(_mm512_load_si512(&y[t]), ut); /* b <- y[r-1][t..t+63] + u[r-1][t..t+63] */ \
tmp = _mm512_loadu_si512((uint8_t*)&x2[t] - 1); \
x2t1 = _mm512_mask_blend_epi8(1, tmp, x21_); \
x21_ = _mm512_maskz_set1_epi8(1, *((uint8_t*)&x2[t] + 63)); \
a2= _mm512_add_epi8(x2t1, vt1); \
b2= _mm512_add_epi8(_mm512_load_si512(&y2[t]), ut);
#define __dp_code_block2 \
_mm512_store_si512(&u[t], _mm512_sub_epi8(z, vt1));/* u[r][t..t+15] <- z - v[r-1][t-1..t+14] */ \
_mm512_store_si512(&v[t], _mm512_sub_epi8(z, ut)); /* v[r][t..t+15] <- z - u[r-1][t..t+15] */ \
tmp = _mm512_sub_epi8(z, q_); \
a = _mm512_sub_epi8(a, tmp); \
b = _mm512_sub_epi8(b, tmp); \
tmp = _mm512_sub_epi8(z, q2_); \
a2= _mm512_sub_epi8(a2, tmp); \
b2= _mm512_sub_epi8(b2, tmp);
int r, t, qe = q + e, n_col_, *off = 0, *off_end = 0, tlen_, qlen_, last_st, last_en, wl, wr, max_sc, min_sc, long_thres, long_diff;
int with_cigar = !(flag&KSW_EZ_SCORE_ONLY), approx_max = !!(flag&KSW_EZ_APPROX_MAX);
int32_t *H = 0, H0 = 0, last_H0_t = 0;
uint8_t *qr, *sf, *mem, *mem2 = 0;
__m512i q_, q2_, qe_, qe2_, zero_, sc_mch_, sc_mis_, m1_, sc_N_;
__m512i *u, *v, *x, *y, *x2, *y2, *s, *p = 0;
ksw_reset_extz(ez);
if (m <= 1 || qlen <= 0 || tlen <= 0) return;
if (q2 + e2 < q + e) t = q, q = q2, q2 = t, t = e, e = e2, e2 = t; // make sure q+e no larger than q2+e2
zero_ = _mm512_set1_epi8(0);
q_ = _mm512_set1_epi8(q);
q2_ = _mm512_set1_epi8(q2);
qe_ = _mm512_set1_epi8(q + e);
qe2_ = _mm512_set1_epi8(q2 + e2);
sc_mch_ = _mm512_set1_epi8(mat[0]);
sc_mis_ = _mm512_set1_epi8(mat[1]);
sc_N_ = mat[m*m-1] == 0? _mm512_set1_epi8(-e2) : _mm512_set1_epi8(mat[m*m-1]);
m1_ = _mm512_set1_epi8(m - 1); // wildcard
if (w < 0) w = tlen > qlen? tlen : qlen;
wl = wr = w;
tlen_ = (tlen + 64 - 1) / 64;
n_col_ = qlen < tlen? qlen : tlen;
n_col_ = ((n_col_ < w + 1? n_col_ : w + 1) + 64 - 1) / 64 + 1;
qlen_ = (qlen + 64 - 1) / 64;
for (t = 1, max_sc = mat[0], min_sc = mat[1]; t < m * m; ++t) {
max_sc = max_sc > mat[t]? max_sc : mat[t];
min_sc = min_sc < mat[t]? min_sc : mat[t];
}
if (-min_sc > 2 * (q + e)) return; // otherwise, we won't see any mismatches
long_thres = e != e2? (q2 - q) / (e - e2) - 1 : 0;
if (q2 + e2 + long_thres * e2 > q + e + long_thres * e)
++long_thres;
long_diff = long_thres * (e - e2) - (q2 - q) - e2;
mem = (uint8_t*)kcalloc(km, tlen_ * 8 + qlen_ + 1, 64);
u = (__m512i*)(((size_t)mem + 64 - 1) >> 6 << 6); // 16-byte aligned
v = u + tlen_, x = v + tlen_, y = x + tlen_, x2 = y + tlen_, y2 = x2 + tlen_;
s = y2 + tlen_, sf = (uint8_t*)(s + tlen_), qr = sf + tlen_ * 64;
memset(u, -q - e, tlen_ * 64);
memset(v, -q - e, tlen_ * 64);
memset(x, -q - e, tlen_ * 64);
memset(y, -q - e, tlen_ * 64);
memset(x2, -q2 - e2, tlen_ * 64);
memset(y2, -q2 - e2, tlen_ * 64);
if (!approx_max) {
H = (int32_t*)kmalloc(km, tlen_ * 64 * 4);
for (t = 0; t < tlen_ * 64; ++t) H[t] = KSW_NEG_INF;
}
if (with_cigar) {
mem2 = (uint8_t*)kmalloc(km, ((size_t)(qlen + tlen - 1) * n_col_ + 1) * 64);
p = (__m512i*)(((size_t)mem2 + 64 - 1) >> 6 << 6);
off = (int*)kmalloc(km, (qlen + tlen - 1) * sizeof(int) * 2);
off_end = off + qlen + tlen - 1;
}
for (t = 0; t < qlen; ++t) qr[t] = query[qlen - 1 - t];
memcpy(sf, target, tlen);
for (r = 0, last_st = last_en = -1; r < qlen + tlen - 1; ++r) {
int st = 0, en = tlen - 1, st0, en0, st_, en_;
int8_t x1, x21, v1;
uint8_t *qrr = qr + (qlen - 1 - r);
int8_t *u8 = (int8_t*)u, *v8 = (int8_t*)v, *x8 = (int8_t*)x, *x28 = (int8_t*)x2;
__m512i x1_, x21_, v1_;
// find the boundaries
if (st < r - qlen + 1) st = r - qlen + 1;
if (en > r) en = r;
if (st < (r-wr+1)>>1) st = (r-wr+1)>>1; // take the ceil
if (en > (r+wl)>>1) en = (r+wl)>>1; // take the floor
if (st > en) {
ez->zdropped = 1;
break;
}
st0 = st, en0 = en;
st = st / 64 * 64, en = (en + 64) / 64 * 64 - 1;
// set boundary conditions
if (st > 0) {
if (st - 1 >= last_st && st - 1 <= last_en) {
x1 = x8[st - 1], x21 = x28[st - 1], v1 = v8[st - 1]; // (r-1,s-1) calculated in the last round
} else {
x1 = -q - e, x21 = -q2 - e2;
v1 = -q - e;
}
} else {
x1 = -q - e, x21 = -q2 - e2;
v1 = r == 0? -q - e : r < long_thres? -e : r == long_thres? long_diff : -e2;
}
if (en >= r) {
((int8_t*)y)[r] = -q - e, ((int8_t*)y2)[r] = -q2 - e2;
u8[r] = r == 0? -q - e : r < long_thres? -e : r == long_thres? long_diff : -e2;
}
// loop fission: set scores first
if (!(flag & KSW_EZ_GENERIC_SC)) {
for (t = st0; t <= en0; t += 64) {
__m512i sq, st, tmp;
__mmask64 mask;
sq = _mm512_loadu_si512((__m512i*)&sf[t]);
st = _mm512_loadu_si512((__m512i*)&qrr[t]);
mask = _mm512_cmpeq_epi8_mask(sq, m1_) | _mm512_cmpeq_epi8_mask(st, m1_);
tmp = _mm512_mask_blend_epi8(_mm512_cmpeq_epi8_mask(sq, st), sc_mis_, sc_mch_);
tmp = _mm512_mask_blend_epi8(mask, tmp, sc_N_);
_mm512_storeu_si512((__m512i*)((int8_t*)s + t), tmp);
}
} else {
for (t = st0; t <= en0; ++t)
((uint8_t*)s)[t] = mat[sf[t] * m + qrr[t]];
}
// core loop
x1_ = _mm512_maskz_set1_epi8(1, x1);
x21_ = _mm512_maskz_set1_epi8(1, x21);
v1_ = _mm512_maskz_set1_epi8(1, v1);
st_ = st / 64, en_ = en / 64;
assert(en_ - st_ + 1 <= n_col_);
if (!with_cigar) { // score only
for (t = st_; t <= en_; ++t) {
__m512i z, a, b, a2, b2, xt1, x2t1, vt1, ut, tmp;
__dp_code_block1;
z = _mm512_max_epi8(z, a);
z = _mm512_max_epi8(z, b);
z = _mm512_max_epi8(z, a2);
z = _mm512_max_epi8(z, b2);
z = _mm512_min_epi8(z, sc_mch_);
__dp_code_block2; // save u[] and v[]; update a, b, a2 and b2
_mm512_store_si512(&x[t], _mm512_sub_epi8(_mm512_max_epi8(a, zero_), qe_));
_mm512_store_si512(&y[t], _mm512_sub_epi8(_mm512_max_epi8(b, zero_), qe_));
_mm512_store_si512(&x2[t], _mm512_sub_epi8(_mm512_max_epi8(a2, zero_), qe2_));
_mm512_store_si512(&y2[t], _mm512_sub_epi8(_mm512_max_epi8(b2, zero_), qe2_));
}
} else if (!(flag&KSW_EZ_RIGHT)) { // gap left-alignment
__m512i *pr = p + (size_t)r * n_col_ - st_;
off[r] = st, off_end[r] = en;
for (t = st_; t <= en_; ++t) {
__m512i d, z, a, b, a2, b2, xt1, x2t1, vt1, ut, tmp;
__dp_code_block1;
d = _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(a, z), 1);
z = _mm512_max_epi8(z, a);
d = _mm512_mask_blend_epi8(_mm512_cmpgt_epi8_mask(b, z), d, _mm512_set1_epi8(2));
z = _mm512_max_epi8(z, b);
d = _mm512_mask_blend_epi8(_mm512_cmpgt_epi8_mask(a2, z), d, _mm512_set1_epi8(3));
z = _mm512_max_epi8(z, a2);
d = _mm512_mask_blend_epi8(_mm512_cmpgt_epi8_mask(b2, z), d, _mm512_set1_epi8(4));
z = _mm512_max_epi8(z, b2);
z = _mm512_min_epi8(z, sc_mch_);
__dp_code_block2;
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(a, zero_), 0x08)); // d = a > 0? 1<<3 : 0
_mm512_store_si512(&x[t], _mm512_sub_epi8(_mm512_max_epi8(a, zero_), qe_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(b, zero_), 0x10)); // d = b > 0? 1<<4 : 0
_mm512_store_si512(&y[t], _mm512_sub_epi8(_mm512_max_epi8(b, zero_), qe_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(a2, zero_), 0x20)); // d = a2 > 0? 1<<5 : 0
_mm512_store_si512(&x2[t], _mm512_sub_epi8(_mm512_max_epi8(a2, zero_), qe2_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(b2, zero_), 0x40)); // d = b2 > 0? 1<<6 : 0
_mm512_store_si512(&y2[t], _mm512_sub_epi8(_mm512_max_epi8(b2, zero_), qe2_));
_mm512_store_si512(&pr[t], d);
}
} else { // gap right-alignment
__m512i *pr = p + (size_t)r * n_col_ - st_;
off[r] = st, off_end[r] = en;
for (t = st_; t <= en_; ++t) {
__m512i d, z, a, b, a2, b2, xt1, x2t1, vt1, ut, tmp;
__dp_code_block1;
d = _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(a, z), 1);
z = _mm512_max_epi8(z, a);
d = _mm512_mask_blend_epi8(_mm512_cmpge_epi8_mask(b, z), d, _mm512_set1_epi8(2));
z = _mm512_max_epi8(z, b);
d = _mm512_mask_blend_epi8(_mm512_cmpge_epi8_mask(a2, z), d, _mm512_set1_epi8(3));
z = _mm512_max_epi8(z, a2);
d = _mm512_mask_blend_epi8(_mm512_cmpge_epi8_mask(b2, z), d, _mm512_set1_epi8(4));
z = _mm512_max_epi8(z, b2);
z = _mm512_min_epi8(z, sc_mch_);
__dp_code_block2;
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(a, zero_), 0x08)); // d = a >= 0? 1<<3 : 0
_mm512_store_si512(&x[t], _mm512_sub_epi8(_mm512_max_epi8(a, zero_), qe_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(b, zero_), 0x10)); // d = b >= 0? 1<<4 : 0
_mm512_store_si512(&y[t], _mm512_sub_epi8(_mm512_max_epi8(b, zero_), qe_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(a2, zero_), 0x20)); // d = a2 >= 0? 1<<5 : 0
_mm512_store_si512(&x2[t], _mm512_sub_epi8(_mm512_max_epi8(a2, zero_), qe2_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(b2, zero_), 0x40)); // d = b2 >= 0? 1<<6 : 0
_mm512_store_si512(&y2[t], _mm512_sub_epi8(_mm512_max_epi8(b2, zero_), qe2_));
_mm512_store_si512(&pr[t], d);
}
}
if (!approx_max) { // find the exact max with a 32-bit score array
int32_t max_H, max_t;
// compute H[], max_H and max_t
if (r > 0) {
int32_t HH[16], tt[16], en1 = st0 + (en0 - st0) / 16 * 16, i;
__m512i max_H_, max_t_;
max_H = H[en0] = en0 > 0? H[en0-1] + u8[en0] : H[en0] + v8[en0]; // special casing the last element
max_t = en0;
max_H_ = _mm512_set1_epi32(max_H);
max_t_ = _mm512_set1_epi32(max_t);
for (t = st0; t < en1; t += 16) { // this implements: H[t]+=v8[t]; if(H[t]>max_H) max_H=H[t],max_t=t;
__m512i H1, t_;
__mmask64 tmp2;
H1 = _mm512_loadu_si512((__m512i*)&H[t]);
t_ = _mm512_cvtepi8_epi32(_mm_loadu_si128((__m128i*)&v8[t]));
H1 = _mm512_add_epi32(H1, t_);
_mm512_storeu_si512((__m512i*)&H[t], H1);
t_ = _mm512_set1_epi32(t);
tmp2 = _mm512_cmpgt_epi32_mask(H1, max_H_);
max_H_ = _mm512_mask_blend_epi32(tmp2, max_H_, H1);
max_t_ = _mm512_mask_blend_epi32(tmp2, max_t_, t_);
}
_mm512_storeu_si512((__m512i*)HH, max_H_);
_mm512_storeu_si512((__m512i*)tt, max_t_);
for (i = 0; i < 16; ++i)
if (max_H < HH[i]) max_H = HH[i], max_t = tt[i] + i;
for (; t < en0; ++t) { // for the rest of values that haven't been computed with SSE
H[t] += (int32_t)v8[t];
if (H[t] > max_H)
max_H = H[t], max_t = t;
}
} else H[0] = v8[0] - qe, max_H = H[0], max_t = 0; // special casing r==0
// update ez
if (en0 == tlen - 1 && H[en0] > ez->mte)
ez->mte = H[en0], ez->mte_q = r - en;
if (r - st0 == qlen - 1 && H[st0] > ez->mqe)
ez->mqe = H[st0], ez->mqe_t = st0;
if (ksw_apply_zdrop(ez, 1, max_H, r, max_t, zdrop, e2)) break;
if (r == qlen + tlen - 2 && en0 == tlen - 1)
ez->score = H[tlen - 1];
} else { // find approximate max; Z-drop might be inaccurate, too.
if (r > 0) {
if (last_H0_t >= st0 && last_H0_t <= en0 && last_H0_t + 1 >= st0 && last_H0_t + 1 <= en0) {
int32_t d0 = v8[last_H0_t];
int32_t d1 = u8[last_H0_t + 1];
if (d0 > d1) H0 += d0;
else H0 += d1, ++last_H0_t;
} else if (last_H0_t >= st0 && last_H0_t <= en0) {
H0 += v8[last_H0_t];
} else {
++last_H0_t, H0 += u8[last_H0_t];
}
} else H0 = v8[0] - qe, last_H0_t = 0;
if ((flag & KSW_EZ_APPROX_DROP) && ksw_apply_zdrop(ez, 1, H0, r, last_H0_t, zdrop, e2)) break;
if (r == qlen + tlen - 2 && en0 == tlen - 1)
ez->score = H0;
}
last_st = st, last_en = en;
//for (t = st0; t <= en0; ++t) printf("(%d,%d)\t(%d,%d,%d,%d)\t%d\n", r, t, ((int8_t*)u)[t], ((int8_t*)v)[t], ((int8_t*)x)[t], ((int8_t*)y)[t], H[t]); // for debugging
}
kfree(km, mem);
if (!approx_max) kfree(km, H);
if (with_cigar) { // backtrack
int rev_cigar = !!(flag & KSW_EZ_REV_CIGAR);
if (!ez->zdropped && !(flag&KSW_EZ_EXTZ_ONLY)) {
ksw_backtrack(km, 1, rev_cigar, 0, (uint8_t*)p, off, off_end, n_col_*64, tlen-1, qlen-1, &ez->m_cigar, &ez->n_cigar, &ez->cigar);
} else if (!ez->zdropped && (flag&KSW_EZ_EXTZ_ONLY) && ez->mqe + end_bonus > (int)ez->max) {
ez->reach_end = 1;
ksw_backtrack(km, 1, rev_cigar, 0, (uint8_t*)p, off, off_end, n_col_*64, ez->mqe_t, qlen-1, &ez->m_cigar, &ez->n_cigar, &ez->cigar);
} else if (ez->max_t >= 0 && ez->max_q >= 0) {
ksw_backtrack(km, 1, rev_cigar, 0, (uint8_t*)p, off, off_end, n_col_*64, ez->max_t, ez->max_q, &ez->m_cigar, &ez->n_cigar, &ez->cigar);
}
kfree(km, mem2); kfree(km, off);
}
}
#endif // __AVX512BW__

116
ksw2_extd2_sse.c
View File

@@ -5,7 +5,14 @@
#ifdef __SSE2__
#if defined(__AVX2__)
#if defined(__AVX512BW__)
#include <immintrin.h>
#define SIMD_INT __m512i
#define SIMD_SHIFT 6
#define simd_func(func) _mm512_##func
#define simd_funcw(func) _mm512_##func##_si512
#elif defined(__AVX2__)
#include <immintrin.h>
#define SIMD_INT __m256i
#define SIMD_SHIFT 5
@@ -31,6 +38,7 @@
#define SIMD_WIDTH (1<<SIMD_SHIFT)
#if !defined(__AVX512BW__)
#if defined(__AVX2__)
static inline __m256i simd_slli_1(__m256i x)
{
@@ -44,10 +52,14 @@ static inline __m256i simd_srli_last(__m256i x)
static inline __m128i simd_slli_1(__m128i x) { return _mm_slli_si128(x, 1); }
static inline __m128i simd_srli_last(__m128i x) { return _mm_srli_si128(x, 15); }
#endif
#endif // ~__AVX512BW__
#ifdef KSW_CPU_DISPATCH
#if defined(__AVX2__)
#if defined(__AVX512BW__)
void ksw_extd2_avx512(void *km, int qlen, const uint8_t *query, int tlen, const uint8_t *target, int8_t m, const int8_t *mat,
int8_t q, int8_t e, int8_t q2, int8_t e2, int w, int zdrop, int end_bonus, int flag, ksw_extz_t *ez)
#elif defined(__AVX2__)
void ksw_extd2_avx2(void *km, int qlen, const uint8_t *query, int tlen, const uint8_t *target, int8_t m, const int8_t *mat,
int8_t q, int8_t e, int8_t q2, int8_t e2, int w, int zdrop, int end_bonus, int flag, ksw_extz_t *ez)
#elif defined(__SSE4_1__)
@@ -62,6 +74,24 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
int8_t q, int8_t e, int8_t q2, int8_t e2, int w, int zdrop, int end_bonus, int flag, ksw_extz_t *ez)
#endif // ~KSW_CPU_DISPATCH
{
#if defined(__AVX512BW__)
#define __dp_code_block1 \
z = _mm512_load_si512(&s[t]); \
tmp = _mm512_loadu_si512((uint8_t*)&x[t] - 1); \
xt1 = _mm512_mask_blend_epi8(1, tmp, x1_); \
x1_ = _mm512_maskz_set1_epi8(1, *((uint8_t*)&x[t] + 63)); \
tmp = _mm512_loadu_si512((uint8_t*)&v[t] - 1); \
vt1 = _mm512_mask_blend_epi8(1, tmp, v1_); \
v1_ = _mm512_maskz_set1_epi8(1, *((uint8_t*)&v[t] + 63)); \
a = _mm512_add_epi8(xt1, vt1); \
ut = _mm512_load_si512(&u[t]); \
b = _mm512_add_epi8(_mm512_load_si512(&y[t]), ut); \
tmp = _mm512_loadu_si512((uint8_t*)&x2[t] - 1); \
x2t1 = _mm512_mask_blend_epi8(1, tmp, x21_); \
x21_ = _mm512_maskz_set1_epi8(1, *((uint8_t*)&x2[t] + 63)); \
a2= _mm512_add_epi8(x2t1, vt1); \
b2= _mm512_add_epi8(_mm512_load_si512(&y2[t]), ut);
#else
#define __dp_code_block1 \
z = simd_funcw(load)(&s[t]); \
xt1 = simd_funcw(load)(&x[t]); /* xt1 <- x[r-1][t..t+15] */ \
@@ -81,6 +111,7 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
x21_= tmp; \
a2= simd_func(add_epi8)(x2t1, vt1); \
b2= simd_func(add_epi8)(simd_funcw(load)(&y2[t]), ut);
#endif // ~__AVX512BW__
#define __dp_code_block2 \
simd_funcw(store)(&u[t], simd_func(sub_epi8)(z, vt1));/* u[r][t..t+15] <- z - v[r-1][t-1..t+14] */ \
@@ -114,7 +145,9 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
sc_N_ = mat[m*m-1] == 0? simd_func(set1_epi8)(-e2) : simd_func(set1_epi8)(mat[m*m-1]);
m1_ = simd_func(set1_epi8)(m - 1); // wildcard
#if defined(__AVX2__)
#if defined(__AVX512BW__)
mask1_ = _mm512_maskz_set1_epi8(1, 0xff);
#elif defined(__AVX2__)
mask1_ = _mm256_setr_epi32(0xff, 0, 0, 0, 0, 0, 0, 0);
#elif defined(__SSE2__)
mask1_ = _mm_setr_epi32(0xff, 0, 0, 0);
@@ -197,15 +230,21 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
// loop fission: set scores first
if (!(flag & KSW_EZ_GENERIC_SC)) {
for (t = st0; t <= en0; t += SIMD_WIDTH) {
SIMD_INT sq, st, tmp, mask;
SIMD_INT sq, st, tmp;
sq = simd_funcw(loadu)((SIMD_INT*)&sf[t]);
st = simd_funcw(loadu)((SIMD_INT*)&qrr[t]);
mask = simd_funcw(or)(simd_func(cmpeq_epi8)(sq, m1_), simd_func(cmpeq_epi8)(st, m1_));
#if defined(__AVX512BW__)
__mmask64 mask = _mm512_cmpeq_epi8_mask(sq, m1_) | _mm512_cmpeq_epi8_mask(st, m1_);
tmp = _mm512_mask_blend_epi8(_mm512_cmpeq_epi8_mask(sq, st), sc_mis_, sc_mch_);
tmp = _mm512_mask_blend_epi8(mask, tmp, sc_N_);
#elif defined(__SSE4_1__) || defined(__AVX2__)
SIMD_INT mask = simd_funcw(or)(simd_func(cmpeq_epi8)(sq, m1_), simd_func(cmpeq_epi8)(st, m1_));
tmp = simd_func(cmpeq_epi8)(sq, st);
#if defined(__SSE4_1__) || defined(__AVX2__)
tmp = simd_func(blendv_epi8)(sc_mis_, sc_mch_, tmp);
tmp = simd_func(blendv_epi8)(tmp, sc_N_, mask);
#elif defined(__SSE2__) // emulate blendv
SIMD_INT mask = simd_funcw(or)(simd_func(cmpeq_epi8)(sq, m1_), simd_func(cmpeq_epi8)(st, m1_));
tmp = simd_func(cmpeq_epi8)(sq, st);
tmp = _mm_or_si128(_mm_andnot_si128(tmp, sc_mis_), _mm_and_si128(tmp, sc_mch_));
tmp = _mm_or_si128(_mm_andnot_si128(mask, tmp), _mm_and_si128(mask, sc_N_));
#endif
@@ -225,7 +264,7 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
for (t = st_; t <= en_; ++t) {
SIMD_INT z, a, b, a2, b2, xt1, x2t1, vt1, ut, tmp;
__dp_code_block1;
#if defined(__SSE4_1__) || defined(__AVX2__)
#if defined(__SSE4_1__) || defined(__AVX2__) || defined(__AVX512BW__)
z = simd_func(max_epi8)(z, a);
z = simd_func(max_epi8)(z, b);
z = simd_func(max_epi8)(z, a2);
@@ -264,6 +303,26 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
for (t = st_; t <= en_; ++t) {
SIMD_INT d, z, a, b, a2, b2, xt1, x2t1, vt1, ut, tmp;
__dp_code_block1;
#if defined(__AVX512BW__)
d = _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(a, z), 1);
z = _mm512_max_epi8(z, a);
d = _mm512_mask_blend_epi8(_mm512_cmpgt_epi8_mask(b, z), d, _mm512_set1_epi8(2));
z = _mm512_max_epi8(z, b);
d = _mm512_mask_blend_epi8(_mm512_cmpgt_epi8_mask(a2, z), d, _mm512_set1_epi8(3));
z = _mm512_max_epi8(z, a2);
d = _mm512_mask_blend_epi8(_mm512_cmpgt_epi8_mask(b2, z), d, _mm512_set1_epi8(4));
z = _mm512_max_epi8(z, b2);
z = _mm512_min_epi8(z, sc_mch_);
__dp_code_block2;
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(a, zero_), 0x08)); // d = a > 0? 1<<3 : 0
_mm512_store_si512(&x[t], _mm512_sub_epi8(_mm512_max_epi8(a, zero_), qe_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(b, zero_), 0x10)); // d = b > 0? 1<<4 : 0
_mm512_store_si512(&y[t], _mm512_sub_epi8(_mm512_max_epi8(b, zero_), qe_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(a2, zero_), 0x20)); // d = a2 > 0? 1<<5 : 0
_mm512_store_si512(&x2[t], _mm512_sub_epi8(_mm512_max_epi8(a2, zero_), qe2_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpgt_epi8_mask(b2, zero_), 0x40)); // d = b2 > 0? 1<<6 : 0
_mm512_store_si512(&y2[t], _mm512_sub_epi8(_mm512_max_epi8(b2, zero_), qe2_));
#else
#if defined(__SSE4_1__) || defined(__AVX2__)
d = simd_funcw(and)(simd_func(cmpgt_epi8)(a, z), simd_func(set1_epi8)(1)); // d = a > z? 1 : 0
z = simd_func(max_epi8)(z, a);
@@ -289,7 +348,7 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
z = _mm_or_si128(_mm_andnot_si128(tmp, z), _mm_and_si128(tmp, b2));
tmp = _mm_cmplt_epi8(sc_mch_, z);
z = _mm_or_si128(_mm_and_si128(tmp, sc_mch_), _mm_andnot_si128(tmp, z));
#endif
#endif // ~__SSE2__
__dp_code_block2;
tmp = simd_func(cmpgt_epi8)(a, zero_);
simd_funcw(store)(&x[t], simd_func(sub_epi8)(simd_funcw(and)(tmp, a), qe_));
@@ -303,6 +362,7 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
tmp = simd_func(cmpgt_epi8)(b2, zero_);
simd_funcw(store)(&y2[t], simd_func(sub_epi8)(simd_funcw(and)(tmp, b2), qe2_));
d = simd_funcw(or)(d, simd_funcw(and)(tmp, simd_func(set1_epi8)(0x40))); // d = b > 0? 1<<6 : 0
#endif // ~__AVX512BW__
simd_funcw(store)(&pr[t], d);
}
} else { // gap right-alignment
@@ -311,6 +371,26 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
for (t = st_; t <= en_; ++t) {
SIMD_INT d, z, a, b, a2, b2, xt1, x2t1, vt1, ut, tmp;
__dp_code_block1;
#if defined(__AVX512BW__)
d = _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(a, z), 1);
z = _mm512_max_epi8(z, a);
d = _mm512_mask_blend_epi8(_mm512_cmpge_epi8_mask(b, z), d, _mm512_set1_epi8(2));
z = _mm512_max_epi8(z, b);
d = _mm512_mask_blend_epi8(_mm512_cmpge_epi8_mask(a2, z), d, _mm512_set1_epi8(3));
z = _mm512_max_epi8(z, a2);
d = _mm512_mask_blend_epi8(_mm512_cmpge_epi8_mask(b2, z), d, _mm512_set1_epi8(4));
z = _mm512_max_epi8(z, b2);
z = _mm512_min_epi8(z, sc_mch_);
__dp_code_block2;
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(a, zero_), 0x08)); // d = a >= 0? 1<<3 : 0
_mm512_store_si512(&x[t], _mm512_sub_epi8(_mm512_max_epi8(a, zero_), qe_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(b, zero_), 0x10)); // d = b >= 0? 1<<4 : 0
_mm512_store_si512(&y[t], _mm512_sub_epi8(_mm512_max_epi8(b, zero_), qe_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(a2, zero_), 0x20)); // d = a2 >= 0? 1<<5 : 0
_mm512_store_si512(&x2[t], _mm512_sub_epi8(_mm512_max_epi8(a2, zero_), qe2_));
d = _mm512_or_si512(d, _mm512_maskz_set1_epi8(_mm512_cmpge_epi8_mask(b2, zero_), 0x40)); // d = b2 >= 0? 1<<6 : 0
_mm512_store_si512(&y2[t], _mm512_sub_epi8(_mm512_max_epi8(b2, zero_), qe2_));
#else
#if defined(__SSE4_1__) || defined(__AVX2__)
d = simd_funcw(andnot)(simd_func(cmpgt_epi8)(z, a), simd_func(set1_epi8)(1)); // d = z > a? 0 : 1
z = simd_func(max_epi8)(z, a);
@@ -336,7 +416,7 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
z = _mm_or_si128(_mm_and_si128(tmp, z), _mm_andnot_si128(tmp, b2));
tmp = _mm_cmplt_epi8(sc_mch_, z);
z = _mm_or_si128(_mm_and_si128(tmp, sc_mch_), _mm_andnot_si128(tmp, z));
#endif
#endif // ~__SSE2__
__dp_code_block2;
tmp = simd_func(cmpgt_epi8)(zero_, a);
simd_funcw(store)(&x[t], simd_func(sub_epi8)(simd_funcw(andnot)(tmp, a), qe_));
@@ -350,6 +430,7 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
tmp = simd_func(cmpgt_epi8)(zero_, b2);
simd_funcw(store)(&y2[t], simd_func(sub_epi8)(simd_funcw(andnot)(tmp, b2), qe2_));
d = simd_funcw(or)(d, simd_funcw(andnot)(tmp, simd_func(set1_epi8)(0x40))); // d = b > 0? 1<<6 : 0
#endif // ~__AVX512BW__
simd_funcw(store)(&pr[t], d);
}
}
@@ -363,10 +444,12 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
max_t = en0;
max_H_ = simd_func(set1_epi32)(max_H);
max_t_ = simd_func(set1_epi32)(max_t);
for (t = st0; t < en1; t += SIMD_WIDTH/4) { // this implements: H[t]+=v8[t]-qe; if(H[t]>max_H) max_H=H[t],max_t=t;
SIMD_INT H1, tmp, t_;
for (t = st0; t < en1; t += SIMD_WIDTH/4) { // this implements: H[t]+=v8[t]; if(H[t]>max_H) max_H=H[t],max_t=t;
SIMD_INT H1, t_;
H1 = simd_funcw(loadu)((SIMD_INT*)&H[t]);
#if defined(__AVX2__)
#if defined(__AVX512BW__)
t_ = _mm512_cvtepi8_epi32(_mm_loadu_si128((__m128i*)&v8[t]));
#elif defined(__AVX2__)
t_ = _mm256_setr_epi32(v8[t], v8[t+1], v8[t+2], v8[t+3], v8[t+4], v8[t+5], v8[t+6], v8[t+7]);
#elif defined(__SSE2__)
t_ = _mm_setr_epi32(v8[t], v8[t+1], v8[t+2], v8[t+3]);
@@ -374,11 +457,16 @@ void ksw_extd2_sse(void *km, int qlen, const uint8_t *query, int tlen, const uin
H1 = simd_func(add_epi32)(H1, t_);
simd_funcw(storeu)((SIMD_INT*)&H[t], H1);
t_ = simd_func(set1_epi32)(t);
tmp = simd_func(cmpgt_epi32)(H1, max_H_);
#if defined(__SSE4_1__) || defined(__AVX2__)
#if defined(__AVX512BW__)
__mmask64 tmp = _mm512_cmpgt_epi32_mask(H1, max_H_);
max_H_ = _mm512_mask_blend_epi32(tmp, max_H_, H1);
max_t_ = _mm512_mask_blend_epi32(tmp, max_t_, t_);
#elif defined(__SSE4_1__) || defined(__AVX2__)
SIMD_INT tmp = simd_func(cmpgt_epi32)(H1, max_H_);
max_H_ = simd_func(blendv_epi8)(max_H_, H1, tmp);
max_t_ = simd_func(blendv_epi8)(max_t_, t_, tmp);
#elif defined(__SSE2__)
SIMD_INT tmp = simd_func(cmpgt_epi32)(H1, max_H_);
max_H_ = simd_funcw(or)(simd_funcw(and)(tmp, H1), simd_funcw(andnot)(tmp, max_H_));
max_t_ = simd_funcw(or)(simd_funcw(and)(tmp, t_), simd_funcw(andnot)(tmp, max_t_));
#endif

2
main.c
View File

@@ -6,7 +6,7 @@
#include "mmpriv.h"
#include "ketopt.h"
#define MM_VERSION "2.14-r897-avx2-dirty"
#define MM_VERSION "2.14-r903-avx2-dirty"
#ifdef __linux__
#include <sys/resource.h>