Heng Li
bf8246f872
Release minimap2-2.1-r311
2017-08-25 13:35:55 +08:00
Heng Li
5cbd776651
test data for spliced alignment
2017-08-25 13:17:56 +08:00
Heng Li
0fe1a224ab
r309: improved SAM header output
2017-08-25 10:35:58 +08:00
Heng Li
240f6caaff
backup manuscript
2017-08-24 22:05:14 +08:00
Heng Li
b8bdac7e64
backup
2017-08-22 17:45:01 +08:00
Heng Li
19e4b2aab0
backup
2017-08-20 22:10:03 +08:00
Heng Li
ce859dbe1c
evaluate introns
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this simplies the metrics
2017-08-20 21:54:59 +08:00
Heng Li
a4c41f64a5
the final version
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to be replaced by intron-eval
2017-08-20 21:54:35 +08:00
Heng Li
5ed2faf270
minor tuning to the matching rules
2017-08-19 16:21:49 +08:00
Heng Li
8058c85b72
moved appendix to methods; detailed splice aln
2017-08-18 23:33:57 +08:00
Heng Li
993a2bb521
r301: separate introns from deletions
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When an intron is adjacent to a deletion, the old code count both as introns,
which lead to an inaccurate exon boundary.
2017-08-18 15:31:15 +08:00
Heng Li
64c1389e1a
Merge branch 'master' into splice
2017-08-17 23:39:27 +08:00
Heng Li
81cff97208
r299: support -h: output to stdout; return 0
2017-08-17 23:38:31 +08:00
Heng Li
bbb37d95f2
support inserting RG lines
2017-08-17 23:34:09 +08:00
Heng Li
2cde8d257c
r297: bidirectional RNA alignment
2017-08-17 06:02:44 -04:00
Heng Li
b5f5929bf9
r296: expose splicing related options to CLI
2017-08-13 21:37:51 -04:00
Heng Li
28f86688ab
r295: gap closure from the middle of non-HPC k
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This WILL slightly affect the result of genomic mapping, but hopefully
in the good direction.
2017-08-12 23:48:43 -04:00
Heng Li
43506edbc5
backup: preliminary boundary alignment
2017-08-12 23:10:14 -04:00
Heng Li
bcfe00d2ad
minor formatting changes
2017-08-12 19:09:33 -04:00
Heng Li
17c19e5819
exts2 working
2017-08-12 19:06:59 -04:00
Heng Li
61eef0575c
separate out spliced alignment; not right yet
2017-08-12 18:54:32 -04:00
Heng Li
53b3265d84
r290: in techrep, explain spliced alignment
2017-08-12 15:40:49 -04:00
Heng Li
a23df2dc91
r289: changed CLI help only
2017-08-12 12:40:07 -04:00
Heng Li
5a74088b74
r288: changed max intron length to 200k
2017-08-12 12:39:21 -04:00
Heng Li
d240318741
r287: refined CLI options and manpage
2017-08-12 12:26:04 -04:00
Heng Li
0f4c823b0c
r286: ignore introns when computing max seg score
2017-08-12 10:58:16 -04:00
Heng Li
2d11aaa830
option to print all exons for debugging
2017-08-12 10:04:16 -04:00
Heng Li
30b8cb4672
option to print correct exons
2017-08-11 17:50:21 -04:00
Heng Li
0c1760bc86
bugfix; print errors; better rules
2017-08-11 16:28:52 -04:00
Heng Li
a99358bc3d
r282: reduced intron cost; added eval script
2017-08-11 00:06:01 -04:00
Heng Li
163fa36ee6
r281: don't open long gaps on query
2017-08-10 15:04:59 -04:00
Heng Li
c59b0781bc
r280: output introns as "N" in the cdna mode
2017-08-09 11:45:02 -04:00
Heng Li
7429b12164
Merge branch 'master' into cdna
2017-08-08 22:00:24 -04:00
Heng Li
9e1125edda
r277: abort if query/-d missing ( #11 )
2017-08-08 21:46:15 -04:00
Heng Li
4db0d1034b
Show travis CI status
2017-08-08 21:32:56 -04:00
Heng Li
3dbe23b34e
Merge branch 'dev'
2017-08-08 21:30:32 -04:00
Heng Li
6840370f3c
Release minimap2-2.0 (r275)
2017-08-08 21:16:25 -04:00
Heng Li
7f9f659b6a
r274: CLI option to change max ref gap
2017-08-08 11:39:23 -04:00
Heng Li
1a7d782131
r273: cdna mapping mode for testing
...
Differences from the typical mapping mode:
* banded alignment disabled
* log gap cost during chaining
* zero long-gap extension during alignment
* up to 100kb (by default) reference gap
* bad seeding not filtered (to tune later)
2017-08-08 11:31:49 -04:00
Heng Li
4badf2fcbf
avoid wasted memory allocation for backtrack
2017-08-08 11:29:46 -04:00
Heng Li
0137d0dfab
command lines used for read simulation
2017-08-07 13:41:40 -04:00
Heng Li
5b10667967
sim-eval.js to support mason2 read names and SAM
2017-08-07 13:28:33 -04:00
Heng Li
bd1541dce1
renamed simulation-related scripts
2017-08-07 13:26:25 -04:00
Heng Li
1597f2b030
convert mason2 SAM to fastq
2017-08-07 12:45:34 -04:00
Heng Li
ce927d2aee
Merge branch 'master' into dev
2017-08-07 12:44:07 -04:00
Heng Li
8c2917b391
Added citation.
2017-08-06 21:30:47 -04:00
Heng Li
9fcf8b6315
added basic travis CI
2017-08-04 15:33:40 -04:00
Heng Li
3217178d4a
fixed k8 download page
2017-08-04 14:53:00 -04:00
Heng Li
b40598fa91
added paf2aln.js example
2017-08-04 14:51:33 -04:00
Heng Li
269b8661b9
minor clarification
2017-08-04 14:49:25 -04:00
Heng Li
890d7bbd5b
added README for misc scripts
2017-08-04 14:46:31 -04:00
Heng Li
1aca0d5098
copied sam2paf.js here for completeness
2017-08-04 14:44:37 -04:00
Heng Li
68d99f0edb
Merge branch 'cs-tag' into dev
2017-08-04 14:31:46 -04:00
Heng Li
fd66ab5413
blast-like output working
2017-08-04 14:31:21 -04:00
Heng Li
71f82759af
convert paf to maf
2017-08-04 13:05:46 -04:00
Heng Li
648cdd8a3b
minor wording changes
2017-08-04 10:21:10 -04:00
Heng Li
7e231cfd3a
minor wording improvement
2017-08-03 21:28:01 -04:00
Heng Li
95d3c30ae3
rephrasing a bit to avoid the apparent TeX bug
...
Several hours sank into this. Damned...
2017-08-03 20:19:00 -04:00
Heng Li
f57fd8c790
added one transition phrase
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as there are no subsubsections now
2017-08-03 18:01:48 -04:00
Heng Li
c70b20ee6d
removed subsubsection
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TeX Live 2016 doesn't work with section and content on the same line.
2017-08-03 17:58:36 -04:00
Heng Li
e8d00a8c8c
removed trailing ^M
2017-08-03 17:20:43 -04:00
Heng Li
ed4efd77bc
minor modifications
...
I will submit this version arXiv. There is definitely room for improvement, but
as a semi-formal technical report, it should be good for now.
2017-08-03 12:47:36 -04:00
Heng Li
295874ea30
spell check
2017-08-03 12:17:58 -04:00
Heng Li
9ec5f51afb
the first draft
2017-08-03 12:12:55 -04:00
Heng Li
28ab4d1f72
backup
2017-08-02 22:59:58 -04:00
Heng Li
6c9390b54a
backup
2017-08-02 19:52:31 -04:00
Heng Li
9306299e4d
added benchmark results
2017-08-01 15:12:49 -04:00
Heng Li
0c563e1868
Merge branch 'dev' into tex
2017-08-01 13:53:16 -04:00
Heng Li
8b1e36c609
minor tweaks to the evaluation script
2017-08-01 13:52:29 -04:00
Heng Li
d933a263d7
backup
2017-08-01 13:29:02 -04:00
Heng Li
7542b4b40a
Makefile for TeX
2017-08-01 10:42:33 -04:00
Heng Li
d6181de844
added tech notes
2017-08-01 10:38:33 -04:00
Heng Li
12cea727b8
r238: bugfix to cs - rev sequence not complemented
2017-08-01 10:33:21 -04:00
Heng Li
cd105b47f2
r237: fixed a bug in outputting cs:Z
2017-07-31 14:49:39 -04:00
Heng Li
35f232c3fa
r236: in cs tag, output differences in lowercase
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for easy eyeballing
2017-07-31 12:17:48 -04:00
Heng Li
4c0713ee14
r235: optionally output tag cs in PAF
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cs encodes the query, the reference sequence and CIGAR.
2017-07-31 12:06:49 -04:00
Heng Li
46de0fbdad
Merge pull request #8 from rikuu/master
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fix self-comparison in index parameter override check
2017-07-30 15:10:29 -04:00
Heng Li
d8d4d29b68
Release minimap2-2.0rc1-r232
2017-07-30 14:32:40 -04:00
Heng Li
e51dfd0330
added NEWS
2017-07-30 14:20:03 -04:00
Heng Li
1f78e1ee53
r230: code formatting changes only
2017-07-30 12:31:40 -04:00
Heng Li
5934d68772
r229: a new way to prevent out-of-band backtrack
2017-07-29 23:52:30 -04:00
Heng Li
fa99d28d34
r228: reduced unnecessary INV alignment
2017-07-29 20:21:53 -04:00
Heng Li
d08b7a0c51
r227: use local alignment for INV alignment
2017-07-29 17:40:53 -04:00
Heng Li
da3db3c095
r226: only try inv alignment for primary
2017-07-29 14:09:35 -04:00
Heng Li
783ead6f47
r225: removed a debugging line
2017-07-29 13:21:38 -04:00
Heng Li
19d6ec885e
r224: inversion alignment around Z-drop break
2017-07-29 13:09:10 -04:00
Heng Li
120bebc290
ake
2017-07-29 11:01:49 -04:00
Heng Li
5e3eecd6d4
r222: no effective changes
2017-07-29 10:31:46 -04:00
Heng Li
2179e9e24b
r221: output SA in the SAM output
2017-07-28 23:08:39 -04:00
Heng Li
84922cfe41
clarify that wrong seeding mainly occurs in LCRs
2017-07-28 14:33:15 -04:00
Heng Li
ebbe9c1eb8
r219: fixed a bug caused by skipping tandem seeds
2017-07-28 14:06:56 -04:00
Heng Li
c672690564
r218: increase the frequency of SW slightly
2017-07-28 13:30:42 -04:00
Heng Li
f4fee60188
r217: ignore tandem seeds during alignment
...
This helps a tiny bit.
2017-07-28 12:26:56 -04:00
Heng Li
254280b8af
r216: a bit cleanup; identical output to r215
2017-07-28 11:54:18 -04:00
Heng Li
fc965805f7
r215: bring back a log gap component
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Otherwise chaining may more often break a long gap into several gaps.
2017-07-28 00:17:19 -04:00
Heng Li
667b32a516
added algorithm overview
2017-07-27 18:50:39 -04:00
Heng Li
2c79580649
r213: more careful solution to wrong seeds
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a little better, but not good enough!
2017-07-27 13:19:11 -04:00
Heng Li
b927838495
r212: better heuristic to fix wrong seeding
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but not good enough. Will explore more.
2017-07-27 11:24:51 -04:00
Heng Li
371e20cc7c
r211: a better heurstic to reduce false seeds
2017-07-26 23:56:38 -04:00
Heng Li
8b08a2ec41
added first-only and all-primary modes to eval
2017-07-26 19:32:26 -04:00