position table; unfinished

This commit is contained in:
Heng Li
2020-03-25 19:17:07 -04:00
parent 585bbbe213
commit e116f6e09d
3 changed files with 92 additions and 19 deletions
+1 -1
View File
@@ -67,7 +67,7 @@ void init_opt(hifiasm_opt_t* asm_opt)
asm_opt->k_mer_length = 41;
asm_opt->mz_win = 41;
asm_opt->bf_shift = 37;
asm_opt->high_factor = 10.0f;
asm_opt->high_factor = 7.0f;
asm_opt->no_HPC = 0;
asm_opt->k_mer_min_freq = 3;
asm_opt->k_mer_max_freq = 66;
+1
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@@ -276,6 +276,7 @@ static kh_inline khint_t __kh_h2b(khint_t hash, khint_t bits) { return hash * 26
KHASHL_INIT(KH_LOCAL, HType, prefix##_m, HType##_m_bucket_t, prefix##_m_hash, prefix##_m_eq) \
SCOPE HType *prefix##_init(void) { return prefix##_m_init(); } \
SCOPE void prefix##_destroy(HType *h) { prefix##_m_destroy(h); } \
SCOPE void prefix##_resize(HType *h, khint_t new_n_buckets) { prefix##_m_resize(h, new_n_buckets); } \
SCOPE khint_t prefix##_get(const HType *h, khkey_t key) { HType##_m_bucket_t t; t.key = key; return prefix##_m_getp(h, &t); } \
SCOPE int prefix##_del(HType *h, khint_t k) { return prefix##_m_del(h, k); } \
SCOPE khint_t prefix##_put(HType *h, khkey_t key, int *absent) { HType##_m_bucket_t t; t.key = key; return prefix##_m_putp(h, &t, absent); }
+90 -18
View File
@@ -142,16 +142,7 @@ static int yak_ch_insert_list(yak_ch_t *h, int create_new, int n, const uint64_t
}
return n_ins;
}
/*
static int yak_ch_get(const yak_ch_t *h, uint64_t x)
{
int mask = (1<<h->pre) - 1;
yak_ht_t *g = h->h[x&mask].h;
khint_t k;
k = yak_ht_get(g, x >> h->pre << YAK_COUNTER_BITS);
return k == kh_end(g)? -1 : kh_key(g, k)&YAK_MAX_COUNT;
}
*/
/*** generate histogram ***/
typedef struct {
@@ -233,7 +224,7 @@ KHASHL_MAP_INIT(static klib_unused, yak_pt_t, yak_pt, uint64_t, uint64_t, yak_ch
typedef struct {
yak_pt_t *h;
uint64_t n, m;
uint64_t n;
ha_seed_t *a;
} ha_pt1_t;
@@ -243,6 +234,67 @@ typedef struct {
ha_pt1_t *h;
} ha_pt_t;
typedef struct {
const yak_ch_t *ch;
ha_pt_t *ph;
} pt_gen_aux_t;
static void worker_pt_gen(void *data, long i, int tid) // callback for kt_for()
{
pt_gen_aux_t *a = (pt_gen_aux_t*)data;
ha_pt1_t *b = &a->ph->h[i];
yak_ht_t *g = a->ch->h[i].h;
khint_t k;
for (k = 0, b->n = 0; k != kh_end(g); ++k) {
if (kh_exist(g, k)) {
int absent;
khint_t l;
l = yak_pt_put(b->h, kh_key(g, k) >> YAK_COUNTER_BITS << YAK_COUNTER_BITS, &absent);
kh_val(b->h, l) = b->n;
b->n += kh_key(g, k) & YAK_MAX_COUNT;
}
}
CALLOC(b->a, b->n);
}
ha_pt_t *ha_pt_gen(const yak_ch_t *ch, int n_thread)
{
pt_gen_aux_t a;
int i;
ha_pt_t *ph;
CALLOC(ph, 1);
ph->k = ch->k, ph->pre = ch->pre, ph->tot = ch->tot;
CALLOC(ph->h, 1<<ph->pre);
for (i = 0; i < 1<<ph->pre; ++i) {
ph->h[i].h = yak_pt_init();
yak_pt_resize(ph->h[i].h, kh_size(ch->h[i].h));
}
a.ch = ch, a.ph = ph;
kt_for(n_thread, worker_pt_gen, &a, 1<<ph->pre);
return ph;
}
static int ha_pt_insert_list(ha_pt_t *h, int n, const ha_mz1_t *a)
{
int j, mask = (1<<h->pre) - 1, n_ins = 0;
ha_pt1_t *g;
if (n == 0) return 0;
g = &h->h[a[0].x&mask];
for (j = 0; j < n; ++j) {
uint64_t x = a[j].x >> h->pre;
khint_t k;
ha_seed_t *s;
if ((a[j].x&mask) != (a[0].x&mask)) continue;
k = yak_pt_get(g->h, x<<YAK_COUNTER_BITS);
if (k == kh_end(g->h)) continue;
assert((kh_key(g->h, k)&YAK_MAX_COUNT) < YAK_MAX_COUNT);
s = &g->a[kh_val(g->h, k) + (kh_key(g->h, k)&YAK_MAX_COUNT)];
s->rid = a[j].rid, s->pos = a[j].pos, s->rev = a[j].rev, s->span = a[j].span;
++kh_key(g->h, k);
}
return n_ins;
}
/**********************************
* Buffer for counting all k-mers *
**********************************/
@@ -251,6 +303,7 @@ typedef struct {
int n, m;
uint64_t n_ins;
uint64_t *a;
ha_mz1_t *b;
} ch_buf_t;
static inline void ch_insert_buf(ch_buf_t *buf, int p, uint64_t y) // insert a k-mer $y to a linear buffer
@@ -264,6 +317,17 @@ static inline void ch_insert_buf(ch_buf_t *buf, int p, uint64_t y) // insert a k
b->a[b->n++] = y;
}
static inline void pt_insert_buf(ch_buf_t *buf, int p, const ha_mz1_t *y)
{
int pre = y->x & ((1<<p) - 1);
ch_buf_t *b = &buf[pre];
if (b->n == b->m) {
b->m = b->m < 8? 8 : b->m + (b->m>>1);
REALLOC(b->b, b->m);
}
b->b[b->n++] = *y;
}
static void count_seq_buf(ch_buf_t *buf, int k, int p, int len, const char *seq) // insert k-mers in $seq to linear buffer $buf
{
int i, l;
@@ -313,6 +377,7 @@ typedef struct { // global data structure for kt_pipeline()
int create_new, is_store;
kseq_t *ks;
yak_ch_t *h;
ha_pt_t *ph;
} pl_data_t;
typedef struct { // data structure for each step in kt_pipeline()
@@ -329,8 +394,10 @@ static void worker_for_insert(void *data, long i, int tid) // callback for kt_fo
{
st_data_t *s = (st_data_t*)data;
ch_buf_t *b = &s->buf[i];
yak_ch_t *h = s->p->h;
b->n_ins += yak_ch_insert_list(h, s->p->create_new, b->n, b->a);
if (s->p->ph)
b->n_ins += ha_pt_insert_list(s->p->ph, b->n, b->b);
else
b->n_ins += yak_ch_insert_list(s->p->h, s->p->create_new, b->n, b->a);
}
static void worker_for_mz(void *data, long i, int tid)
@@ -390,6 +457,7 @@ static void *worker_count(void *data, int step, void *in) // callback for kt_pip
if (!p->is_store) free(s->seq[i]);
}
} else { // minimizers only
uint32_t j;
// compute minimizers
CALLOC(s->mz, s->n_seq);
CALLOC(s->mz_buf, p->opt->n_thread);
@@ -398,10 +466,14 @@ static void *worker_count(void *data, int step, void *in) // callback for kt_pip
free(s->mz_buf[i].a);
free(s->mz_buf);
// insert minimizers
for (i = 0; i < s->n_seq; ++i) {
uint32_t j;
for (j = 0; j < s->mz[i].n; ++j)
ch_insert_buf(s->buf, p->opt->pre, s->mz[i].a[j].x);
if (p->ph) {
for (i = 0; i < s->n_seq; ++i)
for (j = 0; j < s->mz[i].n; ++j)
pt_insert_buf(s->buf, p->opt->pre, &s->mz[i].a[j]);
} else {
for (i = 0; i < s->n_seq; ++i)
for (j = 0; j < s->mz[i].n; ++j)
ch_insert_buf(s->buf, p->opt->pre, s->mz[i].a[j].x);
}
for (i = 0; i < s->n_seq; ++i) {
free(s->mz[i].a);
@@ -550,7 +622,7 @@ void *ha_gen_mzidx(const hifiasm_opt_t *asm_opt, const void *flt_tab)
fprintf(stderr, "[M::%s] count[%d] = %ld (for sanity check)\n", __func__, YAK_MAX_COUNT, (long)cnt[YAK_MAX_COUNT]);
peak_hom = yak_analyze_count(YAK_N_COUNTS, cnt, &peak_het);
if (peak_hom > 0) fprintf(stderr, "[M::%s] peak_hom: %d; peak_het: %d\n", __func__, peak_hom, peak_het);
yak_ch_shrink(h, 2, YAK_MAX_COUNT, asm_opt->thread_num);
yak_ch_shrink(h, 2, YAK_MAX_COUNT - 1, asm_opt->thread_num);
yak_ch_destroy(h);
return 0;
}