Heng Li
395c8d678a
r815: fixed a memory leak
2018-07-15 22:11:32 -04:00
Heng Li
0517972d02
Release minimap2-2.11 (r797)
2018-06-21 00:04:08 -04:00
Heng Li
154d2caf5b
r784: support the =/X CIGAR operators ( #156 )
2018-05-30 16:11:22 -04:00
Heng Li
734ac379bb
r770: matching N bases not working properly ( #155 )
2018-04-30 19:55:23 -04:00
Heng Li
aef7b0744c
r768: shortened preset; added dv tag ( #25 )
...
Also added asm20 to command line help (#151 )
2018-04-24 12:48:54 -04:00
Heng Li
2d7ec75d50
Release minimap2-2.10 (r761)
2018-03-27 11:45:44 -04:00
Heng Li
5ef9580b17
r753: change bandwidth in ava-ont to 2000bp
2018-03-23 10:15:23 -04:00
Heng Li
08bd2123b6
r752: option to copy comments to output ( #136 )
2018-03-23 10:04:33 -04:00
Heng Li
8766d286df
r751: optionally output MD ( #118 )
2018-03-22 14:15:33 -04:00
Heng Li
d135feb1a5
response to reviewers' comments, round 2
2018-03-15 21:59:57 -04:00
Heng Li
bdc615c1d4
r741: added --min-occ-floor to improve #107
2018-03-12 14:32:27 -04:00
Heng Li
eeb314edd6
Release minimap2-2.9 (r720)
2018-02-24 09:31:09 -05:00
Heng Li
54a42aafe5
keep documents in sync
2018-02-15 17:21:09 -05:00
Heng Li
997ab9bb2e
Fixed the description of --dual
2018-02-01 15:11:51 -05:00
Heng Li
53ce317e59
Release minimap2-2.8 (r672)
2018-02-01 12:50:20 -05:00
Heng Li
da6947cfa3
r671: cleanup command line options
2018-01-31 13:59:52 -05:00
Heng Li
6205fa6f21
document --heap-sort
2018-01-26 15:15:40 -05:00
Heng Li
0454e6be91
explain -M in the manpage
2018-01-18 11:47:11 -05:00
Heng Li
33f8157961
r655: options to map to one strand of the ref #91
2018-01-16 10:34:30 -05:00
Heng Li
eecc06086f
Released minimap2-2.7 (r654)
2018-01-09 13:16:00 -05:00
Heng Li
eb819c29e8
Release minimap2-2.6 (r623)
2017-12-12 11:09:59 -05:00
Heng Li
98a6e52c06
r618: heuristics to avoid tiny terminal exons
2017-12-11 00:57:55 -05:00
Heng Li
0e42628ef6
r611: document --idx-no-seq; better inv aln
2017-12-08 13:16:18 -05:00
Heng Li
3b518271ee
Release minimap2-2.5 (r572)
2017-11-11 11:29:28 -05:00
Heng Li
99a2709913
r567: minor change to #56
2017-11-09 19:17:45 -05:00
Heng Li
21a46ba652
Release minimap2-2.4 (r555)
2017-11-06 12:54:02 -05:00
Heng Li
192217a10c
r539: use --splice-flank=yes by default
...
In human/mouse, the GTr..yAG pattern occurs to 91/92% of all GT-AG introns.
Modeling r..y clearly leads to higher accuracy. However, in SIRV, this
percentage is reduced to ~60%. The default "--splice --splice-flank=yes"
leads to lower accuracy. If someone benchmark minimap2 on SIRV, this would be
bad, but minimap2 is developed for practical applications, not for benchmarks.
I will live with that.
2017-10-28 22:29:55 -04:00
Heng Li
79b0caca95
r537: model the next base to GT/AG
...
[PMID:18688272] shows that the base following GT tends to be A or G (i.e. R) in
both human and yeast, and that the base preceeding AG tends to be C or T (i.e.
Y). In the new model, we pay no cost to GTr..yAG, but we pay half of the cost
if there is no r or y. This improves the junction accuracy when mapping to
human and mouse and decreases the accuacy when mapping to SIRV. My guess is
that SIRV does not honor this trend. Need to investigate in future.
Also in this commit, --cost-non-gt-ag is aliased to -C. The default is changed
to 9 instead of 5. I also added --splice-flank to enable the above model. This
may become the default once I confirm my hypothesis on SIRV.
2017-10-28 00:25:01 -04:00
Heng Li
306e4541f8
Released minimap2-2.3 (r531)
2017-10-22 23:13:35 -04:00
Heng Li
04cf4ebf5e
r518: increased the default -K to 500M
...
This helps multi-thread performance for ultra-long reads.
2017-10-17 13:21:29 -04:00
Heng Li
7c555f9b7e
r508: use two I/O threads for mapping
...
-x sr applies this option by default
2017-10-12 14:56:01 -04:00
Heng Li
f150257a0d
r487: demote "map10k"; improved README
2017-10-07 19:19:40 -04:00
Heng Li
ae2adf04d4
r476: multi-file fragment mode working
2017-10-05 15:39:26 -04:00
Heng Li
b839758335
r475: added --cs=none; updated manpage
2017-10-05 15:27:37 -04:00
Heng Li
7d50e646dd
r466: detect multi-part index more smartly
...
though it might not work in an extremely rare case: the end of a sequence ends
at X*16384 and it is the last sequence in a batch. This can be resolved by
never letting the kstream_t buffer empty.
2017-10-04 17:32:58 -04:00
Heng Li
7a9b4db874
replaced --approx-ext with --sr
...
--sr disables Z-drop and may come with other heurstics
2017-09-20 10:51:18 -04:00
Heng Li
ea5a0cd17d
Release minimap2-2.2 (r409)
2017-09-17 20:08:47 -04:00
Heng Li
cf93e5c0a1
more functional minimap2.py; added categories
2017-09-17 17:06:39 -04:00
Heng Li
0f7455cefa
r365: documented the "sr" preset
2017-09-14 12:57:21 -04:00
Heng Li
ef3f7ea2f2
Release minimap2-2.1.1 (r341)
2017-09-06 13:46:51 -04:00
Heng Li
bf8246f872
Release minimap2-2.1-r311
2017-08-25 13:35:55 +08:00
Heng Li
0fe1a224ab
r309: improved SAM header output
2017-08-25 10:35:58 +08:00
Heng Li
bbb37d95f2
support inserting RG lines
2017-08-17 23:34:09 +08:00
Heng Li
b5f5929bf9
r296: expose splicing related options to CLI
2017-08-13 21:37:51 -04:00
Heng Li
53b3265d84
r290: in techrep, explain spliced alignment
2017-08-12 15:40:49 -04:00
Heng Li
5a74088b74
r288: changed max intron length to 200k
2017-08-12 12:39:21 -04:00
Heng Li
d240318741
r287: refined CLI options and manpage
2017-08-12 12:26:04 -04:00
Heng Li
6840370f3c
Release minimap2-2.0 (r275)
2017-08-08 21:16:25 -04:00
Heng Li
d8d4d29b68
Release minimap2-2.0rc1-r232
2017-07-30 14:32:40 -04:00
Heng Li
1f78e1ee53
r230: code formatting changes only
2017-07-30 12:31:40 -04:00
